Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “High-grade Glioma of the Brain”

175 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 175 results

Testing effectiveness (Phase 2)Looking for participantsNCT01906385
What this trial is testing

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

Who this might be right for
Glioma
Cerenome 55
Early research (Phase 1)Study completedNCT00074243
What this trial is testing

CC-8490 in Treating Patients With Recurrent or Refractory High-Grade Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT00509431
What this trial is testing

Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Jonsson Comprehensive Cancer Center 19
Early research (Phase 1)Ended earlyNCT00826930
What this trial is testing

Trans Sodium Crocetinate (TSC) Study of Intra-tumoral Oxygen Concentration, Safety, and Pharmacokinetics in Patients With High Grade Glioma

Who this might be right for
High Grade Glioma
Diffusion Pharmaceuticals Inc 1
Testing effectiveness (Phase 2)Looking for participantsNCT05843253
What this trial is testing

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more
Nationwide Children's Hospital 120
Early research (Phase 1)Study completedNCT02529072
What this trial is testing

Nivolumab With DC Vaccines for Recurrent Brain Tumors

Who this might be right for
Malignant GliomaAstrocytomaGlioblastoma
Gary Archer Ph.D. 6
Testing effectiveness (Phase 2)UnknownNCT00360945
What this trial is testing

Cisplatin and Temozolomide in Treating Young Patients With Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Children's Cancer and Leukaemia Group 87
Not applicableUnknownNCT01317888
What this trial is testing

Access Protocol for MAB-425 Radiolabeled With I-125 for High Grade Gliomas

Who this might be right for
Glioblastoma MultiformeAstrocytoma Anaplastic Foci
Drexel University 11
Early research (Phase 1)Ended earlyNCT01269411
What this trial is testing

RO4929097 in Treating Patients With Recurrent Invasive Gliomas

Who this might be right for
Adult Anaplastic OligodendrogliomaAdult Brain Stem GliomaAdult Giant Cell Glioblastoma+4 more
National Cancer Institute (NCI) 22
Testing effectiveness (Phase 2)Study completedNCT01817751
What this trial is testing

Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma

Who this might be right for
GlioblastomaRecurrent Adult Brain NeoplasmMalignant Glioma+1 more
Virginia Commonwealth University 47
Not applicableNot Yet RecruitingNCT07164053
What this trial is testing

Evaluation of Image Quality and Safety of the MyVeo Surgical Visualization Headset During Standard Neurosurgical and Reconstructive Procedures Using Compatible Microscopes.

Who this might be right for
High-Grade Glioma (WHO III-IV)Cerebral Vascular Conditions Requiring Surgical InterventionConditions Requiring Plastic and Reconstructive Surgery
Leica Microsystems (Schweiz) AG 32
Not applicableStudy completedNCT04734444
What this trial is testing

SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue

Who this might be right for
Brain TumourHigh Grade GliomaLow-grade Glioma+1 more
SonoClear AS 45
Testing effectiveness (Phase 2)Looking for participantsNCT07243470
What this trial is testing

Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors

Who this might be right for
GliomaCNS Tumor, AdultCNS Tumor, Childhood
Centre Leon Berard 70
Testing effectiveness (Phase 2)Ended earlyNCT00636805
What this trial is testing

Aloxi for Prevention of Chemotherapy Induced Nausea and Vomiting in Malignant Glioma Patients Receiving Irinotecan With Bevacizumab

Who this might be right for
Brain Cancer
Duke University 63
Early research (Phase 1)Study completedNCT00720564
What this trial is testing

Radiation Therapy, Arsenic Trioxide, and Temozolomide in Treating Patients With Newly Diagnosed High-Grade Glioma

Who this might be right for
Brain and Central Nervous System Tumors
City of Hope Medical Center 18
Early research (Phase 1)UnknownNCT03423992
What this trial is testing

Personalized Chimeric Antigen Receptor T Cell Immunotherapy for Patients With Recurrent Malignant Gliomas

Who this might be right for
GliomaMalignant Glioma of BrainRecurrence Tumor
Xuanwu Hospital, Beijing 100
Early research (Phase 1)Study completedNCT00611728
What this trial is testing

Ph I SU011248 + Irinotecan in Treatment of Pts w MG

Who this might be right for
Glioblastoma
Duke University 25
Not applicableLooking for participantsNCT06146725
What this trial is testing

The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)

Who this might be right for
GlioblastomaGlioblastoma, IDH-wildtypeGlioblastoma Multiforme+2 more
Jasper Gerritsen 564
Not applicableStudy completedNCT00201903
What this trial is testing

The Roles of Tissue Factor in Malignant Gliomas

Who this might be right for
Venous ThromboembolismBrain Tumors
Ontario Clinical Oncology Group (OCOG) 30
Testing effectiveness (Phase 2)UnknownNCT02839954
What this trial is testing

CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor

Who this might be right for
Hepatocellular CarcinomaNon-small Cell Lung CancerPancreatic Carcinoma+4 more
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10
Next Page