Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “High-risk Locally Advanced Colorectal Cancer”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 17 of 0 results

Not applicableStudy completedNCT01226979
What this trial is testing

Study of High-Dose-Rate Endorectal Brachytherapy (HDRBT) in the Treatment of Locally Advanced Low Rectal Cancer

Who this might be right for
Rectal Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT03997435
What this trial is testing

FOLFOXIRI With or Without Intensification for Rectal Cancer

Who this might be right for
Rectal Cancer
CCTU 72
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07297030
What this trial is testing

SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer

Who this might be right for
Rectal Cancer
Sun Yat-sen University 37
Testing effectiveness (Phase 2)Looking for participantsNCT06362369
What this trial is testing

Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Who this might be right for
Advanced CancerAdvanced Solid TumorMelanoma+15 more
7 Hills Pharma, LLC 126
Testing effectiveness (Phase 2)Looking for participantsNCT05592626
What this trial is testing

A Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsGenital Neoplasm, FemaleUrogenital Neoplasms+11 more
Marengo Therapeutics, Inc. 366
Testing effectiveness (Phase 2)UnknownNCT04801511
What this trial is testing

Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Zhou Fuxiang 60
Not applicableStudy completedNCT04679597
What this trial is testing

Total Neoadjuvant Therapy Versus Standard Therapy of Locally Advanced Rectal Cancer With High Risk Factors for Failure

Who this might be right for
Rectal Cancer
Institute of Oncology Ljubljana 161
Early research (Phase 1)Looking for participantsNCT07503808
What this trial is testing

IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

Who this might be right for
Esophageal Squamous Cell CarcinomaHigh Grade Serous Ovarian CancerHead and Neck Squamous Cell Carcinoma+5 more
IDEAYA Biosciences 150
Testing effectiveness (Phase 2)UnknownNCT03924466
What this trial is testing

Repeatability of 68-GaNOTA-Anti-HER2 VHH1 PET/CT in Breast Carcinoma Patients

Who this might be right for
Metastatic Breast CarcinomaLocally Advanced Breast CancerCancer of Pancreas+11 more
Universitair Ziekenhuis Brussel 55
Testing effectiveness (Phase 2)Active Not RecruitingNCT05054959
What this trial is testing

Consolidation Versus Induction Chemotherapy in Total Neoadjuvant Therapy of Rectal Cancer With High Risk for Recurrence

Who this might be right for
Locally Advanced Rectal Cancer
Institute of Oncology Ljubljana 62
Testing effectiveness (Phase 2)UnknownNCT04674696
What this trial is testing

Short-course Radiotherapy With Induction and Consolidation Chemotherapy in Patients With Locally Advanced Rectal Cancer

Who this might be right for
Rectal CancerTotal Neoadjuvant Treatment
Instituto Nacional de Cancer, Brazil 54
Not applicableUnknownNCT05877573
What this trial is testing

Toripalimab Combined With Neoadjuvant Chemoradiotherapy as First-line Treatment for Locally Advanced,High-Risk,MSS Rectal Cancer

Who this might be right for
Locally AdvancedHigh-RiskRectal Cancer+1 more
Nanfang Hospital, Southern Medical University 53
Large-scale testing (Phase 3)Looking for participantsNCT04215731
What this trial is testing

Neoadjuvant mFOLFOXIRI Plus Bevacizumab in Patients With High-Risk Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Yanhong Deng 582
Testing effectiveness (Phase 2)Looking for participantsNCT05919264
What this trial is testing

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Who this might be right for
CancerColorectal CancerSolid Tumor+12 more
Parabilis Medicines, Inc. 619
Testing effectiveness (Phase 2)Looking for participantsNCT07669220
What this trial is testing

A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial)

Who this might be right for
Rectal AdenocarcinomaHigh-risk Locally AdvancedShort-course Radiotherapy (SCRT)+2 more
Sixth Affiliated Hospital, Sun Yat-sen University 76
Large-scale testing (Phase 3)Looking for participantsNCT06229041
What this trial is testing

Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi)

Who this might be right for
Rectal Cancer
Peking University Cancer Hospital & Institute 472
Testing effectiveness (Phase 2)UnknownNCT04543695
What this trial is testing

Total Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 255