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Results for “High-risk Locally Advanced Colorectal Cancer”

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Showing 20 of 0 results

Large-scale testing (Phase 3)UnknownNCT01064999
What this trial is testing

A Trial of High Intensity Versus Low Intensity Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Fudan University 240
Large-scale testing (Phase 3)Looking for participantsNCT07505472
What this trial is testing

Efficacy and Safety Comparison of Short-course Radiotherapy Followed by CapeOX Chemotherapy Plus Toripalimab With or Without Concurrent Surufatinib in Neoadjuvant Therapy for Mid-to-low Localized Rectal Cancer of High-risk Criteria

Who this might be right for
Rectal Cancer
The First Hospital of Jilin University 212
Testing effectiveness (Phase 2)UnknownNCT04340401
What this trial is testing

Total Neoadjuvant Treatment Plus SHR1210 for High-risk Rectal Cancer and Biomarker Screening Base on Neoantigen

Who this might be right for
Rectal Cancer
Peking University Cancer Hospital & Institute 25
Testing effectiveness (Phase 2)UnknownNCT01826396
What this trial is testing

Standard and High Dose Irinotecan Based on UGT1A1 Genotype for First-line Treatment of Locally Advanced Colon Cancer

Who this might be right for
Colonic Neoplasms
Colorectal Cancer Institute of the Heilongjiang Academy of Medical Sciences 100
Early research (Phase 1)Ended earlyNCT06625515
What this trial is testing

First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients With Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers

Who this might be right for
Advanced Solid TumorsBreast Cancer RecurrentColorectal Cancer Metastatic+3 more
Accent Therapeutics 17
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07403877
What this trial is testing

Neoadjuvant Immunotherapy ± Radiotherapy in MSI-H/dMMR Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer (MSI-H)
Fudan University 114
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07810114
What this trial is testing

Total Neoadjuvant mFOLFOX6 Plus Suvemcitug and Enlonstobart With Selective Omission of Pelvic Radiotherapy for High-Risk Mid-Rectal Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Fudan University 52
Testing effectiveness (Phase 2)Study completedNCT02460198
What this trial is testing

Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Previously-Treated Locally Advanced Unresectable or Metastatic Colorectal Cancer (MK-3475-164/KEYNOTE-164)

Who this might be right for
Colorectal Carcinoma
Merck Sharp & Dohme LLC 124
Testing effectiveness (Phase 2)Looking for participantsNCT06698757
What this trial is testing

Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Yugui Lian 96
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07248020
What this trial is testing

A Phase II Single-Arm Study of High-Bioavailability Curcumin as Neoadjuvant Chemoradiotherapy in Mid-to-Low Rectal Cancer: Integrated Clinical and Translational Analysis of Tumor Tissue

Who this might be right for
Rectal CancerLocally Advanced Rectal CancerRadiation-Induced Enteritis+2 more
Chang Gung Memorial Hospital 72
Testing effectiveness (Phase 2)Looking for participantsNCT05450029
What this trial is testing

Neoadjuvant Chemoradiotherapy Plus Sintilimab for Intermediate/High Immunoscore Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Yanhong Deng 51
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07765667
What this trial is testing

NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARC

Who this might be right for
Rectal AdenocarcinomaHigh-Risk CancerMSS
Sixth Affiliated Hospital, Sun Yat-sen University 100
Not applicableActive Not RecruitingNCT06337552
What this trial is testing

High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial)

Who this might be right for
Rectal CancerNon-Small Cell Lung Cancer
H. Lee Moffitt Cancer Center and Research Institute 39
Testing effectiveness (Phase 2)UnknownNCT05018182
What this trial is testing

FOLFOXIRI for Neoadjuvant Treatment of High-risk Locally Advanced Colorectal Cancer

Who this might be right for
High-risk Locally Advanced Colorectal CancerNeoadjuvant ChemotherapyFOLFOXIRI Regimen
West China Hospital 69
Testing effectiveness (Phase 2)Study completedNCT01434147
What this trial is testing

Preoperative Combined Induction Chemotherapy With Capecitabine, Oxaliplatin, Bevacizumab and Radiotherapy

Who this might be right for
Rectal Cancer
Austrian Breast & Colorectal Cancer Study Group 25
Not applicableLooking for participantsNCT06831981
What this trial is testing

Hyperthermia With Chemoradiotherapy in Rectal Cancer

Who this might be right for
Rectal Cancer
University Hospital Tuebingen 264
Testing effectiveness (Phase 2)Study completedNCT01481545
What this trial is testing

Bevacizumab With Pelvic Radiotherapy And Primary Chemotherapy in Patients With Poor-Risk Rectal Cancer

Who this might be right for
Rectal Cancer
National Cancer Institute, Naples 62
Testing effectiveness (Phase 2)Looking for participantsNCT07244705
What this trial is testing

ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRC

Who this might be right for
Colorectal Cancer (Diagnosis)Colorectal Cancer MetastaticColorectal Cancer (CRC)+1 more
Anbogen Therapeutics, Inc. 66
Testing effectiveness (Phase 2)UnknownNCT04715633
What this trial is testing

PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability High
Sun Yat-sen University 53
Large-scale testing (Phase 3)Not Yet RecruitingNCT07132008
What this trial is testing

Neoadjuvant CAPOX Plus Tislelizumab vs CAPOX in MSS High-Risk Locally Advanced Colon Cancer

Who this might be right for
Colonic NeoplasmsNeoadjuvant TherapyImmune Checkpoint Inhibitors
First Affiliated Hospital of Guangxi Medical University 94
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