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Results for “High-risk Myelodysplastic Syndromes”

581 trials

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Showing 20 of 581 results

Testing effectiveness (Phase 2)Study completedNCT00553202
What this trial is testing

Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 158
Early research (Phase 1)Study completedNCT00875745
What this trial is testing

Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteLeukemia, Promyelocytic, AcuteMyelodysplastic Syndromes
Indiana University 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT06098313
What this trial is testing

HCT With PTCy in Higher-risk MDS

Who this might be right for
Patients With MDS, Acute Myeloid Leukemia (AML) Evolving From MDS, and Chronic Myelomonocytic Leukemia (CMML)
Asan Medical Center 113
Testing effectiveness (Phase 2)Ended earlyNCT00655395
What this trial is testing

Treatment of Elderly Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic (MD) Syndrome With Laromustine and Infusional Cytarabine

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)
Viron Therapeutics Inc 25
Early research (Phase 1)Study completedNCT00641030
What this trial is testing

Clofarabine and High-Dose Melphalan Followed by Donor Stem Cell Transplant in Patients With Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Myelodysplastic Syndromes

Who this might be right for
LeukemiaMyelodysplastic Syndromes
City of Hope Medical Center 20
Testing effectiveness (Phase 2)Study completedNCT00050154
What this trial is testing

Study of Tipifarnib in Patients With High-Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Myelodysplastic Syndrome
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 82
Testing effectiveness (Phase 2)Ended earlyNCT00740181
What this trial is testing

Decitabine, Cytarabine, GCSF for Refractory AML/MDS

Who this might be right for
MyelodysplasiaLeukemia
Brown University 9
Testing effectiveness (Phase 2)Looking for participantsNCT03661307
What this trial is testing

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+2 more
M.D. Anderson Cancer Center 73
Early research (Phase 1)WithdrawnNCT02786485
What this trial is testing

Study of Matched Unrelated Donor T Cell Infusion for Hematologic Malignancies After Allo-HSCT

Who this might be right for
LeukemiaMyelodysplastic SyndromesLymphomas+2 more
Bellicum Pharmaceuticals
Testing effectiveness (Phase 2)Ended earlyNCT01748240
What this trial is testing

Addition of Vorinostat to Azacitidine in Higher Risk MDS a Phase II add-on Study in Patients With Azacitidine Failure

Who this might be right for
Myelodysplastic Syndrome
Groupe Francophone des Myelodysplasies 21
Testing effectiveness (Phase 2)Study completedNCT00397579
What this trial is testing

DT388IL3 Fusion Protein in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes

Who this might be right for
LeukemiaMyelodysplastic SyndromesBlastic Plasmacytoid Dendritic Cell Neoplasm
University of Texas Southwestern Medical Center 11
Testing effectiveness (Phase 2)WithdrawnNCT04217720
What this trial is testing

SNS-301 Monotherapy in High Risk MDS and CMML

Who this might be right for
Myelodysplastic SyndromesChronic Myelomonocytic Leukemia (CMML)
Sensei Biotherapeutics, Inc.
Testing effectiveness (Phase 2)Study completedNCT00045942
What this trial is testing

PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome (CPKC412A2104 Core); and PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome With Either Wild Type or Mutated FMS-like Tyrosine Kinase 3 (FLT3) (CPKC412A2104E1 and CPKC412A2104E2)

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Novartis Pharmaceuticals 144
Not applicableEnded earlyNCT00443300
What this trial is testing

Effectiveness of Protected Environment Rooms for AML and MDS

Who this might be right for
Acute Myelogenous LeukemiaMyelodysplastic Syndrome
M.D. Anderson Cancer Center 3
Early research (Phase 1)Ended earlyNCT00923234
What this trial is testing

Combination of 5-azacitidine and Lenalidomide in Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML) Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic SyndromesAcute Myelogenous Leukemia
Technische Universität Dresden
Testing effectiveness (Phase 2)Study completedNCT00882102
What this trial is testing

Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (H-R MDS)

Who this might be right for
Acute Myelogenous LeukemiaMyelodysplastic Syndrome
M.D. Anderson Cancer Center 43
Early research (Phase 1)Looking for participantsNCT03896269
What this trial is testing

CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Who this might be right for
Blasts 10-19 Percent of Bone Marrow Nucleated CellsBlasts More Than 5 Percent of Bone Marrow Nucleated CellsHigh Risk Chronic Myelomonocytic Leukemia+4 more
M.D. Anderson Cancer Center 38
Testing effectiveness (Phase 2)WithdrawnNCT04985656
What this trial is testing

Pevonedistat Combined With Decitabine and Cedazuridine in Adults With Higher-risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes (MDS)
Takeda
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06900088
What this trial is testing

Selinexor Combined With Azacitidine Therapy in High-Risk Myeloid Neoplasms Patients

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeChronic Myelomonocytic Leukemia
Institute of Hematology & Blood Diseases Hospital, China 20
Testing effectiveness (Phase 2)Study completedNCT00683046
What this trial is testing

T-Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Hematologic Malignancies

Who this might be right for
Acute Myelogenous LeukemiaLymphoid LeukemiaChronic Myelogenous Leukemia+6 more
University of Chicago 204
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