Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Hippocampal Avoidance”

30 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 30 results

Large-scale testing (Phase 3)Study completedNCT02360215
What this trial is testing

Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases

Who this might be right for
Cognitive ImpairmentMetastatic Malignant Neoplasm in the BrainSolid Neoplasm
NRG Oncology 518
Not applicableUnknownNCT03414944
What this trial is testing

Elective Simultaneous Modulated Accelerated Brain Radiation Therapy for NSCLCs With Limited Brain Metastases

Who this might be right for
Brain Metastases
Shandong Cancer Hospital and Institute 30
Testing effectiveness (Phase 2)UnknownNCT02832635
What this trial is testing

A Clinical Trial on Whole-brain Radiotherapy With Temozolomide Concurrent Chemotherapy or Avoidance of Hippocampus for Patients of Brain Metastases

Who this might be right for
Brain MetastasisRadiation Therapy Complication
Sun Yat-sen University 256
Testing effectiveness (Phase 2)Looking for participantsNCT04343157
What this trial is testing

UCSD Image-Guided Cognitive-Sparing Radiosurgery for Intracranial Lesions

Who this might be right for
Brain Metastases, AdultNeurocognitive FunctionCancer+2 more
Jona Hattangadi-Gluth 90
Not applicableLooking for participantsNCT02504788
What this trial is testing

A Prospective Study of the Impact of Hippocampal Avoidance During Whole Brain Radiotherapy on Neurocognitive Function Decline

Who this might be right for
Brain MetastasisBrain Metastases
Chang Gung Memorial Hospital 100
Not applicableStudy completedNCT02397733
What this trial is testing

Memory Preservation of Prophylactic Cranial Irradiation With Hippocampal Avoidance (PREMER-TRIAL)

Who this might be right for
Small Cell Lung Carcinoma
Grupo de Investigación Clínica en Oncología Radioterapia 150
Large-scale testing (Phase 3)Looking for participantsNCT06457906
What this trial is testing

SRS/SRT/Hypo-RT Versus HA-WBRT for No More Than 10 Brain Metastases in SCLC

Who this might be right for
Small-cell Lung CancerBrain MetastasesSRS+3 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 340
Not applicableActive Not RecruitingNCT06557187
What this trial is testing

Hippocampus-Avoidance Whole-Brain Radiation Therapy With Simultaneous Integrated Boost for BMs of NSCLC

Who this might be right for
Brain MetastasesNon-small Cell Lung Cancer
Yatian Liu 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07505979
What this trial is testing

SMART Trial: Cognitive Sparing Brain Radiotherapy for Multiple Brain Metastases

Who this might be right for
Brain Metastases From Solid Tumors
National Taiwan University Hospital 90
Large-scale testing (Phase 3)Study completedNCT01780675
What this trial is testing

Hippocampus Avoidance PCI vs PCI

Who this might be right for
Small Cell Lung CancerLung Cancer
The Netherlands Cancer Institute 168
Large-scale testing (Phase 3)UnknownNCT04277403
What this trial is testing

HA-WBRT vs SRS in Patients With Multiple Brain Metastases

Who this might be right for
Brain Metastases
Medical University Innsbruck 150
Not applicableActive Not RecruitingNCT04065776
What this trial is testing

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

Who this might be right for
GliomaPilocytic AstrocytomaPilomyxoid Astrocytoma+4 more
St. Jude Children's Research Hospital 48
Not applicableActive Not RecruitingNCT03075072
What this trial is testing

Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial

Who this might be right for
Brain Metastases
Dana-Farber Cancer Institute 196
Not applicableStudy completedNCT02058056
What this trial is testing

Early Hippocampal Avoidance Prophylactic Cranial Irradiation in Patients With LD SCLC

Who this might be right for
Small-Cell Lung Cancer
Swiss Cancer Institute 44
Testing effectiveness (Phase 2)Study completedNCT01227954
What this trial is testing

Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Who this might be right for
Cognitive/Functional EffectsMetastatic CancerUnspecified Adult Solid Tumor, Protocol Specific
Radiation Therapy Oncology Group 113
Testing effectiveness (Phase 2)Looking for participantsNCT07248228
What this trial is testing

Memory Avoidance Whole Brain Radiotherapy vs Hippocampal Avoidance Whole Brain Radiotherapy (Athena 2 Trial)

Who this might be right for
Brain Metastases
Case Comprehensive Cancer Center 90
Not applicableStudy completedNCT05096286
What this trial is testing

Simulation-Free Hippocampal-Avoidance Whole Brain Radiotherapy Using Diagnostic MRI-Based and Cone Beam Computed Tomography-Guided On-Table Adaptive Planning in a Novel Ring Gantry Radiotherapy Device

Who this might be right for
Intracranial Metastatic Disease From Any Solid Malignancy
Washington University School of Medicine 10
Testing effectiveness (Phase 2)UnknownNCT04801342
What this trial is testing

Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain Metastases

Who this might be right for
Metastatic Malignant Neoplasm to Brain
National Taiwan University Hospital 72
Not applicableUnknownNCT02393131
What this trial is testing

Neurocognitive Outcome of Conformal WBRT w/wo Hippocampal Avoidance for Brain Metastases

Who this might be right for
Metastatic Malignant Neoplasm to Brain
National Taiwan University Hospital 70
Large-scale testing (Phase 3)Study completedNCT01942980
What this trial is testing

Evaluation of the Efficacy of Hippocampal Avoidance on the Cognitive Toxicity of Whole-Brain Radiation Therapy After Surgical Resection of Single Brain Metastasis of Breast Cancer

Who this might be right for
Breast CancerBrain Metastasis
Institut Paoli-Calmettes 8
Next Page