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Results for “Histone Deacetylase Inhibitor”

187 trials

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Showing 20 of 187 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT06890585
What this trial is testing

Zanubrutinib, Chidamide, and Rituximab Induction With or Without CHOP Versus R-CHOP in Newly Diagnosed Double-Expressor DLBCL

Who this might be right for
BTK InhibitorsHistone Deacetylase InhibitorDouble Express Diffuse Large B-cell Lymphoma
Li Zhiming 128
Testing effectiveness (Phase 2)Ended earlyNCT00490776
What this trial is testing

Study of Oral LBH589 in Adult Participants With Refractory/Resistant Cutaneous T-Cell Lymphoma (CTCL)

Who this might be right for
Cutaneous T-Cell Lymphoma
Novartis Pharmaceuticals 9
Testing effectiveness (Phase 2)Study completedNCT00289952
What this trial is testing

Valproic Acid and Its Effects on HIV Latent Reservoirs

Who this might be right for
HIV Infections
Jean-Pierre Routy 50
Testing effectiveness (Phase 2)WithdrawnNCT02756663
What this trial is testing

Panobinostat in Combination With Carfilzomib and Dexamethasone in Relapsed or Relapsed and Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Novartis Pharmaceuticals
Early research (Phase 1)Active Not RecruitingNCT02886065
What this trial is testing

PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM

Who this might be right for
Smoldering Multiple Myeloma
Massachusetts General Hospital 19
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07226141
What this trial is testing

Valproate for the Treatment of Residual Amblyopia

Who this might be right for
AmblyopiaAmblyopia UnilateralAmblyopia, Anisometropic+1 more
Boston Children's Hospital 28
Early research (Phase 1)Study completedNCT01106872
What this trial is testing

Bevacizumab, Chemotherapy and Valproic Acid in Advanced Sarcomas

Who this might be right for
SarcomaSoft Tissue SarcomaLocally Advanced Sarcoma+2 more
Mohammed M Milhem 47
Testing effectiveness (Phase 2)Study completedNCT02471430
What this trial is testing

Reducing the Residual Reservoir of HIV-1 Infected Cells in Patients Receiving Antiretroviral Therapy

Who this might be right for
HIV Infection
Massachusetts General Hospital 17
Early research (Phase 1)Study completedNCT00788931
What this trial is testing

A Trial l of Panobinostat Given in Combination With Trastuzumab and Paclitaxel in Adult Female Patients With HER2 Positive Metastatic Breast Cancer

Who this might be right for
HER-2 Positive Breast CancerMetastatic Breast Cancer
Novartis Pharmaceuticals 15
Testing effectiveness (Phase 2)Ended earlyNCT01034657
What this trial is testing

LBH589 Alone or in Combination With Erythropoietin Stimulating Agents (ESA) in Patients With Low or Int-1 Risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic Syndrome (MDS)
Novartis Pharmaceuticals 34
Early research (Phase 1)UnknownNCT01175109
What this trial is testing

Study of Imatinib, a Platelet-derived Growth Factor Receptor Inhibitor, and LBH589, a Histone Deacetylase Inhibitor, in the Treatment of Newly Diagnosed and Recurrent Chordoma

Who this might be right for
Chordoma
Deric M Park MD 36
Early research (Phase 1)Ended earlyNCT00127101
What this trial is testing

An Investigational Study of a Histone Deacetylase (HDAC) Inhibitor Plus Targretin in Cutaneous T-Cell Lymphoma Patients (0683-016)(TERMINATED)

Who this might be right for
Lymphoma
Merck Sharp & Dohme LLC 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT03934567
What this trial is testing

A Multi-Center Phase 2 Study to Evaluate Efficacy and Safety of Oral Abexinostat as Monotherapy in Patients With Relapsed or Refractory Follicular Lymphoma

Who this might be right for
Lymphoma, Follicular
Xynomic Pharmaceuticals, Inc. 87
Testing effectiveness (Phase 2)Looking for participantsNCT04512534
What this trial is testing

Sintilimab Combined With Chidamide in Treating Peripheral T Cell Lymphoma

Who this might be right for
Peripheral T-cell Lymphoma
Fudan University 51
Testing effectiveness (Phase 2)Looking for participantsNCT06220487
What this trial is testing

A Single-arm, Open-label Study of Olverembatinib, CD3/CD19 Bispecific T-cell Engager, and Chidamide in Patients With Newly Diagnosed Ph+ALL

Who this might be right for
Acute Lymphoblastic LeukemiaPhiladelphia ChromosomePhiladelphia-Positive ALL+2 more
Nanfang Hospital, Southern Medical University 67
Testing effectiveness (Phase 2)Study completedNCT00580931
What this trial is testing

Safety Study of Nicotinamide to Treat Alzheimer's Disease

Who this might be right for
Alzheimer's Disease
University of California, Irvine 50
Testing effectiveness (Phase 2)Study completedNCT00867672
What this trial is testing

Study of Decitabine Alone or in Combination With Valproic Acid and All-trans Retinoic Acid in Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
University Hospital Freiburg 204
Early research (Phase 1)Study completedNCT01583283
What this trial is testing

Study of ACY-1215 in Combination With Lenalidomide, and Dexamethasone in Multiple Myeloma

Who this might be right for
Multiple Myeloma
Celgene 38
Testing effectiveness (Phase 2)Study completedNCT00339196
What this trial is testing

5-azacytidine Valproic Acid and ATRA in AML and High Risk MDS

Who this might be right for
Acute Myelogenous Leukaemia (AML)Myelodysplastic Syndrome (MDS)
Assistance Publique - Hôpitaux de Paris 25
Testing effectiveness (Phase 2)Study completedNCT01947140
What this trial is testing

Pralatrexate + Romidepsin in Relapsed/Refractory Lymphoid Malignancies

Who this might be right for
Lymphoid MalignanciesMultiple MyelomaLymphoma+2 more
Jennifer Amengual 57
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