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Results for “Histone Deacetylase Inhibitor”

189 trials

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Showing 20 of 189 results

Early research (Phase 1)Study completedNCT01567709
What this trial is testing

Alisertib in Combination With Vorinostat in Treating Patients With Relapsed or Recurrent Hodgkin Lymphoma, B-Cell Non-Hodgkin Lymphoma, or Peripheral T-Cell Lymphoma

Who this might be right for
Adult B Acute Lymphoblastic LeukemiaAdult T Acute Lymphoblastic LeukemiaAnaplastic Large Cell Lymphoma+32 more
National Cancer Institute (NCI) 34
Early research (Phase 1)Study completedNCT02728492
What this trial is testing

Safety, Tolerability and Pharmacokinetics of Quisinostat, a Histone Deacetylase Inhibitor, in Combination With Chemotherapy

Who this might be right for
Non-small Cell Lung CancerEpithelial Ovarian Cancer
NewVac LLC 51
Early research (Phase 1)Ended earlyNCT01159301
What this trial is testing

Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Adult Acute Basophilic LeukemiaAdult Acute Eosinophilic LeukemiaAdult Acute Megakaryoblastic Leukemia (M7)+16 more
National Cancer Institute (NCI) 44
Testing effectiveness (Phase 2)UnknownNCT01305499
What this trial is testing

A Trial to Evaluate Two Schedules of MS275 in Combination With 5AC in Elderly Patients With Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Hetty Carraway 52
Testing effectiveness (Phase 2)UnknownNCT00866762
What this trial is testing

The Efficacy of MK-0683 in Patients With Polycythaemia Vera and Essential Thrombocythaemia

Who this might be right for
Polycythemia VeraEssential Thrombocythemia
Copenhagen University Hospital at Herlev 60
Testing effectiveness (Phase 2)Study completedNCT00995332
What this trial is testing

Disease Stabilization in AML by Treatment With ATRA, Valproic Acid and Low-dose Cytarabine

Who this might be right for
Acute Myelogenous Leukemia
University of Bergen 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT05694936
What this trial is testing

Combining Sodium Valproate With Standard-of-care EGFR (Epidermal Growth Factor Receptor) Monoclonal Antibody Treatment in Patients With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Australasian Gastro-Intestinal Trials Group 38
Early research (Phase 1)Active Not RecruitingNCT02886065
What this trial is testing

PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM

Who this might be right for
Smoldering Multiple Myeloma
Massachusetts General Hospital 19
Not applicableStudy completedNCT03460444
What this trial is testing

The Effect of Raising Ketones Directly With MCT Oil on Inflammation in Healthy Young Adults

Who this might be right for
MCT Oil Supplementation
University of British Columbia 15
Testing effectiveness (Phase 2)Ended earlyNCT01528501
What this trial is testing

Histone Deacetylases - Gastric Cancer (HDAC-GaCa-2008)

Who this might be right for
Metastatic Gastric Cancer
Technical University of Munich 28
Testing effectiveness (Phase 2)Ended earlyNCT01034657
What this trial is testing

LBH589 Alone or in Combination With Erythropoietin Stimulating Agents (ESA) in Patients With Low or Int-1 Risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic Syndrome (MDS)
Novartis Pharmaceuticals 34
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06890585
What this trial is testing

Zanubrutinib, Chidamide, and Rituximab Induction With or Without CHOP Versus R-CHOP in Newly Diagnosed Double-Expressor DLBCL

Who this might be right for
BTK InhibitorsHistone Deacetylase InhibitorDouble Express Diffuse Large B-cell Lymphoma
Li Zhiming 128
Early research (Phase 1)Ended earlyNCT01174199
What this trial is testing

Temsirolimus and Vorinostat in Treating Patients With Metastatic Prostate Cancer

Who this might be right for
Prostate CancerAdenocarcinoma of the ProstateHormone-resistant Prostate Cancer+2 more
Roswell Park Cancer Institute 13
Testing effectiveness (Phase 2)Study completedNCT01045538
What this trial is testing

Study of Vorinostat Plus Capecitabine (X) and Cisplatin (P) for 1st Line Treatment of Metastatic or Recurrent Gastric Cancer: Zolinza+XP

Who this might be right for
Gastric CancerHistone Deacetylase Inhibitor
Asan Medical Center 45
Early research (Phase 1)UnknownNCT01159418
What this trial is testing

LBH589 Oral in Combination With Carboplatin and Paclitaxel in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Southern Europe New Drug Organization 36
Testing effectiveness (Phase 2)Ended earlyNCT00699296
What this trial is testing

Study of Oral LBH589 in Patients With Cutaneous T-cell Lymphoma and Adult T-cell Leukemia/Lymphoma

Who this might be right for
Cutaneous T-Cell LymphomaLeukemia-Lymphoma, Adult T-Cell
Novartis Pharmaceuticals 4
Early research (Phase 1)Looking for participantsNCT01245179
What this trial is testing

Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease

Who this might be right for
Sickle Cell Disease
Abdullah Kutlar 18
Testing effectiveness (Phase 2)Study completedNCT01200498
What this trial is testing

Study of SB939 in Subjects With Myelofibrosis

Who this might be right for
Myeloproliferative Disorders
M.D. Anderson Cancer Center 23
Early research (Phase 1)Ended earlyNCT00437957
What this trial is testing

Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain Metastases

Who this might be right for
Brain Metastases
H. Lee Moffitt Cancer Center and Research Institute 10
Testing effectiveness (Phase 2)UnknownNCT05076786
What this trial is testing

Chidamide Plus Etoposide and Cisplatin/Carboplatin as First-line Treatment for Extrapulmonary Neuroendocrine Carcinoma

Who this might be right for
Neuroendocrine TumorsNeuroendocrine Carcinoma
Peking Union Medical College Hospital 28
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