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Results for “Histone Deacetylase Inhibitor”

187 trials

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Showing 20 of 187 results

Testing effectiveness (Phase 2)Study completedNCT00928707
What this trial is testing

Phase II Study of GIVINOSTAT (ITF2357) in Combination With Hydroxyurea in Polycythemia Vera

Who this might be right for
Polycythemia Vera
Italfarmaco 45
Early research (Phase 1)Study completedNCT00741234
What this trial is testing

A Phase I Dose Escalation Study of Oral SB939 Administered Alone or With Azacitidine

Who this might be right for
Solid TumorsHematologic MalignanciesMyelodysplastic Syndrome
S*BIO 85
Testing effectiveness (Phase 2)UnknownNCT00772798
What this trial is testing

A Phase I/II Study of Paclitaxel Plus Carboplatin Plus Vorinostat in Recurrent Ovarian Cancer

Who this might be right for
Ovarian Cancer
Herlev Hospital 70
Early research (Phase 1)Study completedNCT00719875
What this trial is testing

HDAC Inhibitor Vorinostat (SAHA) With Capecitabine (Xeloda) Using a New Weekly Dose Regimen for Advanced Breast Cancer

Who this might be right for
Advanced Breast Cancer
Yale University 24
Early research (Phase 1)Study completedNCT00739414
What this trial is testing

Dose-escalating Study of LBH589 in Adult Patients With Advanced Solid Tumors

Who this might be right for
CancerAdvanced Solid Tumor
Novartis Pharmaceuticals 14
Early research (Phase 1)Study completedNCT01023737
What this trial is testing

Hydroxychloroquine + Vorinostat in Advanced Solid Tumors

Who this might be right for
Malignant Solid Tumour
The University of Texas Health Science Center at San Antonio 72
Early research (Phase 1)Active Not RecruitingNCT02886065
What this trial is testing

PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM

Who this might be right for
Smoldering Multiple Myeloma
Massachusetts General Hospital 19
Testing effectiveness (Phase 2)Ended earlyNCT01034657
What this trial is testing

LBH589 Alone or in Combination With Erythropoietin Stimulating Agents (ESA) in Patients With Low or Int-1 Risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic Syndrome (MDS)
Novartis Pharmaceuticals 34
Early research (Phase 1)Ended earlyNCT00437957
What this trial is testing

Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain Metastases

Who this might be right for
Brain Metastases
H. Lee Moffitt Cancer Center and Research Institute 10
Testing effectiveness (Phase 2)Study completedNCT00605657
What this trial is testing

Valproic Acid (Depakote[Registered Trademark]) to Treat Autoimmune Lymphoproliferative Syndrome (ALPS)

Who this might be right for
ALPSHypersplenismLymphadenopathy
Koneti Rao 6
Early research (Phase 1)Ended earlyNCT01174199
What this trial is testing

Temsirolimus and Vorinostat in Treating Patients With Metastatic Prostate Cancer

Who this might be right for
Prostate CancerAdenocarcinoma of the ProstateHormone-resistant Prostate Cancer+2 more
Roswell Park Cancer Institute 13
Testing effectiveness (Phase 2)Study completedNCT00995332
What this trial is testing

Disease Stabilization in AML by Treatment With ATRA, Valproic Acid and Low-dose Cytarabine

Who this might be right for
Acute Myelogenous Leukemia
University of Bergen 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT01038778
What this trial is testing

Entinostat in Combination With Aldesleukin in Treating Patients With Metastatic Kidney Cancer

Who this might be right for
Clear Cell Renal Cell CarcinomaMetastatic Kidney CarcinomaStage III Renal Cell Cancer AJCC v7+1 more
National Cancer Institute (NCI) 47
Early research (Phase 1)Study completedNCT02616874
What this trial is testing

Study to Evaluate the Safety and Effect of HIVconsv Vaccines in Combination With Histone Deacetylase Inhibitor Romidepsin on the Viral Rebound Kinetic After Treatment Interruption in Early Treated HIV-1 Infected Individuals

Who this might be right for
HIV
IrsiCaixa 15
Testing effectiveness (Phase 2)Ended earlyNCT01282476
What this trial is testing

Panobinostat With Rituximab for Relapsed/Refractory Diffuse Large B Cell Lymphoma

Who this might be right for
Diffuse Large B Cell Lymphoma
Massachusetts General Hospital 18
Early research (Phase 1)Study completedNCT02922933
What this trial is testing

Examine the Effect of Omeprazole, Famotidine, and an Acidic Beverage on the Pharmacokinetics of Entinostat in Healthy Adult Subjects

Who this might be right for
VolunteersHealthy VolunteersHuman Volunteers+1 more
Syndax Pharmaceuticals 66
Early research (Phase 1)Study completedNCT01464112
What this trial is testing

A Dose Escalation Study of the Histone Deacetylase Inhibitor (HDACi) JNJ 26481585 in Combination With VELCADE (Bortezomib) and Dexamethasone for Patients With Relapsed Multiple Myeloma

Who this might be right for
Multiple Myeloma
Janssen Research & Development, LLC 18
Testing effectiveness (Phase 2)Study completedNCT01238692
What this trial is testing

A Phase II Study of Oral Panobinostat (LBH589) and Rituximab to Treat Diffuse Large B Cell Lymphoma (DLBCL)

Who this might be right for
Diffuse Large B Cell Lymphoma
Sarit Assouline 42
Early research (Phase 1)Ended earlyNCT00127101
What this trial is testing

An Investigational Study of a Histone Deacetylase (HDAC) Inhibitor Plus Targretin in Cutaneous T-Cell Lymphoma Patients (0683-016)(TERMINATED)

Who this might be right for
Lymphoma
Merck Sharp & Dohme LLC 23
Testing effectiveness (Phase 2)Study completedNCT01486277
What this trial is testing

The Histone Deacetylase Inhibitor (HDACi) Quisinostat (JNJ-26481585) in Patients With Previously Treated Stage Ib-IVa Cutaneous T-cell Lymphoma

Who this might be right for
Lymphoma, T-Cell, Cutaneous
Janssen Research & Development, LLC 26
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