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Results for “Homozygous Familial Hypercholesterolaemia (HoFH)”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Ended earlyNCT00079846
What this trial is testing

Implitapide in Patients With Homozygous Familial Hypercholesterolemia (HoFH) on Maximal Concurrent Lipid-Lowering Therapy

Who this might be right for
Familial Hypercholesterolemia
Medical Research Laboratories International 60
Large-scale testing (Phase 3)UnknownNCT04948008
What this trial is testing

Evaluate the Efficacy and Safety of IBI306 in Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - HomozygousLipid Metabolism DisordersProprotein Convertase Subtilisin/Kexin 9
Shenzhen People's Hospital 8
Not applicableStudy completedNCT03018678
What this trial is testing

Screening Protocol for a Gene Therapy Trial in Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia, Familial
University of Pennsylvania 21
Large-scale testing (Phase 3)Study completedNCT02173158
What this trial is testing

Efficacy and Safety of Lomitapide in Japanese Patients With HoFH on Concurrent Lipid-Lowering Therapy

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Aegerion Pharmaceuticals, Inc. 9
Large-scale testing (Phase 3)Study completedNCT03399786
What this trial is testing

Efficacy and Safety of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 65
Large-scale testing (Phase 3)Study completedNCT00134511
What this trial is testing

Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Patients With Genetic High Cholesterol Disorder

Who this might be right for
Hypercholesterolemia, Familial
Pfizer 30
Testing effectiveness (Phase 2)Study completedNCT06009393
What this trial is testing

Evaluate the Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Beijing Suncadia Pharmaceuticals Co., Ltd 26
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Not applicableActive Not RecruitingNCT06275724
What this trial is testing

Specified Drug-use Survey of Leqvio for s.c. Injection.

Who this might be right for
Familial HypercholesterolaemiaHypercholesterolaemia
Novartis Pharmaceuticals 585
Not applicableActive Not RecruitingNCT06832371
What this trial is testing

Evaluation of the Effect of Lomitapide Treatment on Major Adverse Cardiovascular Events (MACE) in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)Major Adverse Cardiovascular Events (MACE)Dyslipidemia
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 73
Testing effectiveness (Phase 2)Study completedNCT00477594
What this trial is testing

Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia

Who this might be right for
Lipid Metabolism, Inborn ErrorsHypercholesterolemia, Autosomal DominantHyperlipidemias+11 more
Kastle Therapeutics, LLC 21
Not applicableWithdrawnNCT02399852
What this trial is testing

Effects of Lomitapide on Carotid and Aortic Atherosclerosis

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc.
Large-scale testing (Phase 3)Study completedNCT00607373
What this trial is testing

Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia

Who this might be right for
Lipid Metabolism, Inborn ErrorsHypercholesterolemia, Autosomal DominantHyperlipidemias+11 more
Kastle Therapeutics, LLC 51
Not applicableUnknownNCT04080050
What this trial is testing

A Long-term Follow-up Study to Evaluate the Safety and Efficacy of RGX-501

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
REGENXBIO Inc. 8
Testing effectiveness (Phase 2)Study completedNCT01412034
What this trial is testing

Effect of CER-001 on Plaque Volume in Homozygous Familial Hypercholesterolemia (HoFH) Subjects

Who this might be right for
Homozygous Familial Hypercholesterolemia
Cerenis Therapeutics, SA 23
Not applicableLooking for participantsNCT01109368
What this trial is testing

The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository

Who this might be right for
Homozygous Familial Hypercholesterolemia
The Rogosin Institute 60
Not applicableLooking for participantsNCT07470723
What this trial is testing

The ORIGIN-FH Study

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)Homozygous Familial Hypercholesterolemia (HoFH)Familial Hypercholesterolemia
University of Wisconsin, Madison 70
Testing effectiveness (Phase 2)WithdrawnNCT03455777
What this trial is testing

Study of AKCEA-ANGPTL3-LRX (ISIS 703802) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Akcea Therapeutics
Testing effectiveness (Phase 2)Study completedNCT02265952
What this trial is testing

Study of REGN1500 in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 9
Large-scale testing (Phase 3)Not Yet RecruitingNCT07473843
What this trial is testing

Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 12
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