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Results for “Homozygous Familial Hypercholesterolemia”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)WithdrawnNCT03455777
What this trial is testing

Study of AKCEA-ANGPTL3-LRX (ISIS 703802) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Akcea Therapeutics
Testing effectiveness (Phase 2)Study completedNCT02265952
What this trial is testing

Study of REGN1500 in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 9
Large-scale testing (Phase 3)Not Yet RecruitingNCT07473843
What this trial is testing

Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 12
Post-approval studies (Phase 4)Study completedNCT03403374
What this trial is testing

Safety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia HoFH
Amgen 30
Not applicableStudy completedNCT00001204
What this trial is testing

Cardiovascular Evaluation of Patients With High Cholesterol and Normal Volunteers

Who this might be right for
Homozygous Familial Hypercholesterolemic
National Heart, Lung, and Blood Institute (NHLBI) 73
Large-scale testing (Phase 3)Study completedNCT02434497
What this trial is testing

Evaluate the Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 9
Not applicableUnknownNCT03135184
What this trial is testing

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial HypercholesterolemiaHoFH
HDL Therapeutics 6
Large-scale testing (Phase 3)Study completedNCT01588496
What this trial is testing

Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities

Who this might be right for
Homozygous Familial Hypercholesterolemia
Amgen 58
Testing effectiveness (Phase 2)Study completedNCT02472535
What this trial is testing

Study to Evaluate the Effects of MBX-8025 in Patients With HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
Gilead Sciences 13
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07133815
What this trial is testing

Evaluate the Long-term Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Beijing Suncadia Pharmaceuticals Co., Ltd 55
Large-scale testing (Phase 3)Study completedNCT03409744
What this trial is testing

Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 116
Large-scale testing (Phase 3)Study completedNCT00694109
What this trial is testing

An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia

Who this might be right for
Lipid Metabolism, Inborn ErrorsHypercholesterolemia, Autosomal DominantHyperlipidemias+11 more
Kastle Therapeutics, LLC 144
Testing effectiveness (Phase 2)UnknownNCT04455581
What this trial is testing

Determine the Safety, Tolerability, and Efficacy of SHR-1209 in Patients With Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Jiangsu HengRui Medicine Co., Ltd. 8
Not applicableLooking for participantsNCT04370899
What this trial is testing

Early Detection of Familial Hypercholesterolemia in Children

Who this might be right for
Familial HypercholesterolemiaFamilial Hypercholesterolemia - HeterozygousFamilial Hypercholesterolemia - Homozygous
Institut Investigacio Sanitaria Pere Virgili 400
Large-scale testing (Phase 3)Ended earlyNCT01841684
What this trial is testing

Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042)

Who this might be right for
Hyperlipoproteinemia Type IIHomozygous Familial Hypercholesterolemia
Merck Sharp & Dohme LLC 2
Large-scale testing (Phase 3)Study completedNCT06723652
What this trial is testing

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Beijing Suncadia Pharmaceuticals Co., Ltd 55
Not applicableStudy completedNCT04722068
What this trial is testing

Regeneron 1331 Kinetics Sub-Study HoFH

Who this might be right for
Hypercholesterolemia, Familial
University of Pennsylvania 4
Large-scale testing (Phase 3)Study completedNCT03510715
What this trial is testing

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Sanofi 18
Early research (Phase 1)Looking for participantsNCT07491172
What this trial is testing

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

Who this might be right for
CardiovascularMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG 90
Testing effectiveness (Phase 2)Ended earlyNCT05217667
What this trial is testing

Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 18
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