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Results for “Human Challenge Trial”

37 trials

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Showing 20 of 37 results

Early research (Phase 1)Looking for participantsNCT06827470
What this trial is testing

Establishing a Controlled Human Infection Model of Pertactin-deficient Bordetella Pertussis

Who this might be right for
Pertussis (Whooping Cough)
Dalhousie University 60
Early research (Phase 1)Study completedNCT05136599
What this trial is testing

Establishing a Controlled Human Infection Model of Bordetella Pertussis

Who this might be right for
Pertussis
Dalhousie University 79
Not applicableStudy completedNCT04788862
What this trial is testing

Blood-stage Controlled Human Plasmodium Falciparum Malaria Infection in Tanzania

Who this might be right for
MalariaPlasmodium Falciparum
University of Oxford 12
Early research (Phase 1)Study completedNCT02132299
What this trial is testing

Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults

Who this might be right for
MalariaPlasmodium Falciparum Malaria
Sanaria Inc. 67
Testing effectiveness (Phase 2)WithdrawnNCT04480736
What this trial is testing

JNJ-64281802 Against Dengue Serotype 1 Infection in a Dengue Human Challenge Model in Healthy Adult Participants

Who this might be right for
Healthy
Janssen Research & Development, LLC
Early research (Phase 1)Study completedNCT04870138
What this trial is testing

Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial)

Who this might be right for
Gonococcal Infection
National Institute of Allergy and Infectious Diseases (NIAID) 16
Not applicableStudy completedNCT00674336
What this trial is testing

Infectivity of Norovirus in Shellfish Treated With High Hydrostatic Pressure Processing-Human Challenge Study

Who this might be right for
Healthy
Emory University 51
Early research (Phase 1)Looking for participantsNCT07706686
What this trial is testing

Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection

Who this might be right for
Healthy VolunteersDengueHuman Challenge Trial
National Institute of Allergy and Infectious Diseases (NIAID) 200
Early research (Phase 1)Study completedNCT03261401
What this trial is testing

First-in-Human Trial of Single Ascending Dose, Multiple Ascending Dose and Malaria Challenge Model in Healthy Participants

Who this might be right for
Healthy
Merck KGaA, Darmstadt, Germany 88
Early research (Phase 1)Study completedNCT00935623
What this trial is testing

Clinical Trial for the Development of a Safe Malaria Challenge Model That Can be Reproduced in Humans

Who this might be right for
Plasmodium Vivax Malaria
U.S. Army Medical Research and Development Command 12
Not applicableStudy completedNCT05572450
What this trial is testing

Dose, Safety, and Pathogenicity of a New Influenza H1N1 Challenge Strain

Who this might be right for
Influenza A H1N1
Hvivo 70
Early research (Phase 1)Study completedNCT03583606
What this trial is testing

A Trial to Evaluate the Safety and Systems Biology Response of Ebolavirus Zaire Vaccine (ChAd3-EBO-Z)

Who this might be right for
Ebola DiseaseImmunisation
National Institute of Allergy and Infectious Diseases (NIAID) 61
Post-approval studies (Phase 4)UnknownNCT04974294
What this trial is testing

PREVENTING PNEUMOcoccal Disease Through Vaccination (Study 2)

Who this might be right for
Streptococcus Pneumonia
Liverpool School of Tropical Medicine 516
Early research (Phase 1)Study completedNCT01226758
What this trial is testing

Influenza Vaccine Challenge Study in Healthy Subjects

Who this might be right for
Influenza
PepTcell Limited 32
Not applicableStudy completedNCT06613737
What this trial is testing

Dose, Safety, and Pathogenicity of a New Influenza A H3N2 Challenge Strain

Who this might be right for
Influenza A H3N2
Hvivo 33
Testing effectiveness (Phase 2)Study completedNCT00697281
What this trial is testing

OC000459 Dose Finding Study in Hay Fever Sufferers.

Who this might be right for
Allergic Rhinitis
Oxagen Ltd 120
Not applicableActive Not RecruitingNCT06670755
What this trial is testing

ID93/GLA-SE Vaccination + BCG Challenge

Who this might be right for
Tuberculosis
University of Oxford 48
Early research (Phase 1)Study completedNCT05592223
What this trial is testing

Phase I Open Label BCG Clinical Trial Assessing TB Drugs and Vaccines

Who this might be right for
Tuberculosis
Fred Hutchinson Cancer Center 20
Early research (Phase 1)Active Not RecruitingNCT06735209
What this trial is testing

First-in-Human PfSPZ-LARC2 Vaccination/CHMI

Who this might be right for
Malaria
National Institute of Allergy and Infectious Diseases (NIAID) 22
Testing effectiveness (Phase 2)Study completedNCT02601716
What this trial is testing

PfSPZ Vaccine: Dose Optimization With Heterologous Challenge in Healthy Malaria-Naïve Adults

Who this might be right for
Malaria
Sanaria Inc. 92
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