Testing effectiveness (Phase 2)Ended earlyNCT02225496What this trial is testingRobotic Surgery for Oropharyngeal Squamous Cell CarcinomaWho this might be right forOropharyngeal Cancer M.D. Anderson Cancer Center 1
Testing effectiveness (Phase 2)Looking for participantsNCT05686226What this trial is testingE7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated CancersWho this might be right forCervical CancerThroat CancerOropharynx Cancer+18 more Christian Hinrichs 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07628062What this trial is testingPhase 2 Study of NAI, HPV Vaccine, and Nab-Paclitaxel in HPV-Positive Oropharyngeal Cancer Followed by De-Intensified Radiation Compared With Standard ChemoradiationWho this might be right forHPV-Positive Oropharyngeal Squamous Cell CarcinomaOropharyngeal Squamous Cell CarcinomaHead and Neck Cancer ImmunityBio, Inc. 70
Testing effectiveness (Phase 2)Study completedNCT04260126What this trial is testingStudy of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCCWho this might be right forMetastatic Head and Neck CancerRecurrent Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more PDS Biotechnology Corp. 95
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07418034What this trial is testingA Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED)Who this might be right forHead and Neck CancerHead and Neck Squamous Cell CancerHead and Neck Squamous Cell Carcinoma+11 more University of Maryland, Baltimore 132
Not applicableStudy completedNCT06771674What this trial is testingReal-world Study of First Line Pembrolizumab- or Nivolumab-treated HPV-positive Recurrent/Metastatic Oropharyngeal Squamous Cell CarcinomaWho this might be right forOropharyngeal Squamous Cell Carcinoma Hookipa Biotech GmbH 662
Testing effectiveness (Phase 2)Ended earlyNCT03618134What this trial is testingStereotactic Body Radiation Therapy and Durvalumab With or Without Tremelimumab Before Surgery in Treating Participants With Human Papillomavirus Positive Oropharyngeal Squamous Cell CanerWho this might be right forClinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC (American Joint Committee on Cancer) v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+6 more Jonsson Comprehensive Cancer Center
Testing effectiveness (Phase 2)Study completedNCT02858310What this trial is testingE7 TCR T Cells for Human Papillomavirus-Associated CancersWho this might be right forPapillomavirus InfectionsCervical Intraepithelial NeoplasiaCarcinoma In Situ+2 more National Cancer Institute (NCI) 224
Testing effectiveness (Phase 2)Looking for participantsNCT06797986What this trial is testingA Phase I/IIa Clinical Trial to Investigate BVAC-E6E7 in Subjects With HPV Positive HNSCC.Who this might be right forHead and Neck Squamous Cell Carcinoma (HNSCC)HPV (Human Papillomavirus)-Associated CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma Cellid Co., Ltd. 37
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06505551What this trial is testingPhase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive CarcinomaWho this might be right forHPV-Related Squamous Cell CarcinomaHPV-Related Cervical Squamous Cell CarcinomaHPV-Related Vulvar Squamous Cell Carcinoma+4 more SCG Cell Therapy Pte. Ltd. 66
Large-scale testing (Phase 3)UnknownNCT01874171What this trial is testingDetermination of Cetuximab Versus Cisplatin Early and Late Toxicity Events in HPV+ OPSCCWho this might be right forOropharyngeal Squamous Cell Carcinoma University of Warwick 334
Testing effectiveness (Phase 2)Study completedNCT03342911What this trial is testingNivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by SurgeryWho this might be right forName Human Papillomavirus Positive Oropharyngeal Squamous Cell CarcinomaStage II Oropharyngeal Squamous Cell CarcinomaStage III Hypopharyngeal Squamous Cell Carcinoma+19 more Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 34
Testing effectiveness (Phase 2)Ended earlyNCT01221753What this trial is testingDocetaxel/Cisplatin/5-Fluorouracil (TPF) Human Papillomavirus (HPV) Squamous Cell Carcinoma StudyWho this might be right forSquamous Cell Carcinoma of the Head and NeckHuman Papilloma Virus Dana-Farber Cancer Institute 7
Early research (Phase 1)Active Not RecruitingNCT05973487What this trial is testingA Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid TumorsWho this might be right forHead and Neck CancerCervical CancerNon-small Cell Carcinoma+18 more TScan Therapeutics, Inc. 840
Not applicableStudy completedNCT05119036What this trial is testingAdjuvant Treatment Deintensification After Transoral Surgery for Human Papillomavirus-Positive Squamous Cell CarcinomaWho this might be right forSquamous Cell Carcinoma of the OropharynxHPV Positive Oropharyngeal Squamous Cell Carcinoma Indiana University 82
Testing effectiveness (Phase 2)Looking for participantsNCT05491512What this trial is testingReduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat CancerWho this might be right forHPVThroat CancerOropharyngeal Carcinoma+2 more Memorial Sloan Kettering Cancer Center 121
Not applicableEnded earlyNCT02045186What this trial is testingMonitoring of Oral Human Papillomavirus Infection (HPV) in HPV-positive Oropharyngeal Squamous Cell Carcinoma (OPSCC)Who this might be right forCarcinoma, Squamous CellHead and Neck NeoplasmsOropharyngeal Neoplasms UNC Lineberger Comprehensive Cancer Center 1
Not applicableActive Not RecruitingNCT05814549What this trial is testingA Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)Who this might be right forOropharyngeal CancerHPV-Related CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma Memorial Sloan Kettering Cancer Center 9
Testing effectiveness (Phase 2)Study completedNCT02159703What this trial is testingA Single-arm Phase II Study of Post-Transoral Robotic Surgery (TORS) Alone to the Primary Tumor Site and Selective Neck Dissection (SND) Followed by Adjuvant Radiation Therapy (+/- Chemotherapy) to the Regional Nodes for Advanced Stage, Human Papilloma Virus (HPV) Positive, Oropharyngeal CancerWho this might be right forOropharyngeal Cancer Abramson Cancer Center at Penn Medicine 60
Testing effectiveness (Phase 2)Looking for participantsNCT07290621What this trial is testingToripalimab in Combination With Standard Treatment for Human Papillomavirus (HPV) Positive Throat CancerWho this might be right forOropharyngeal Cancer University of Chicago 30