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Results for “Human Papillomavirus-16 Positive”

63 trials

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Showing 20 of 63 results

Early research (Phase 1)Looking for participantsNCT07081984
What this trial is testing

Study of TI-0093 Injection With Recurrent/Metastatic HPV-16 Positive Solid Tumors

Who this might be right for
HPV 16+ Recurrent or Metastatic CancerHNSCCCervical Cancer
Therorna 12
Testing effectiveness (Phase 2)Looking for participantsNCT04852328
What this trial is testing

Three Schedules of CUE-101 Administered Before Surgery or Definitive Chemoradiation Therapy in HLA-A*0201 Positive Patients With Locally Advanced, HPV16-Positive Oropharyngeal Squamous-Cell Carcinoma

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
Washington University School of Medicine 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06505551
What this trial is testing

Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma

Who this might be right for
HPV-Related Squamous Cell CarcinomaHPV-Related Cervical Squamous Cell CarcinomaHPV-Related Vulvar Squamous Cell Carcinoma+4 more
SCG Cell Therapy Pte. Ltd. 66
Testing effectiveness (Phase 2)Looking for participantsNCT07209189
What this trial is testing

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

Who this might be right for
Head and Neck CancerSquamous Cell CarcinomaOral Cavity Cancer+6 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 75
Testing effectiveness (Phase 2)Study completedNCT04180215
What this trial is testing

A Phase 1/2 Study in Patients With HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Other Cancers

Who this might be right for
HPV-Related Squamous Cell Carcinoma
Hookipa Biotech GmbH 198
Early research (Phase 1)Study completedNCT00988559
What this trial is testing

Therapeutic Vaccination for Patients With HPV16+ Cervical Intraepithelial Neoplasia (CIN2/3)

Who this might be right for
HPV16 PositiveCervical Intraepithelial Neoplasia (CIN 2/3)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 132
Early research (Phase 1)Study completedNCT02379520
What this trial is testing

HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA

Who this might be right for
Human Papillomavirus-Related CarcinomaHuman Papillomavirus Positive Oropharyngeal CarcinomaHuman Papillomavirus Positive Cervical Carcinoma+3 more
Baylor College of Medicine 32
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07303751
What this trial is testing

Study Assessing Reduced HPV Infectivity and Transmission in HPV-Positive Women Following Vaccination With 9vHPV

Who this might be right for
HPVHigh-risk HPV (Any Strain)Human Papillomavirus (HPV) Infections
Institut d'Investigació Biomèdica de Bellvitge 80
Not applicableStudy completedNCT03226613
What this trial is testing

New Modalities for Detection of Oropharyngeal Cancer

Who this might be right for
Human Papillomavirus Positive Oropharyngeal Squamous Cell CarcinomaOropharynx CancerBase of Tongue Carcinoma+1 more
Vanderbilt University Medical Center 51
Testing effectiveness (Phase 2)Study completedNCT04260126
What this trial is testing

Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC

Who this might be right for
Metastatic Head and Neck CancerRecurrent Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
PDS Biotechnology Corp. 95
Testing effectiveness (Phase 2)Active Not RecruitingNCT03260023
What this trial is testing

Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers

Who this might be right for
HPV-Related CarcinomaHPV-Related Cervical CarcinomaHPV-Related Anal Squamous Cell Carcinoma+2 more
Transgene 143
Not applicableStudy completedNCT02016833
What this trial is testing

Development of Immunological Assays for the Evaluation of Tumor Antigen Specific Immunity

Who this might be right for
Ovarian Serous AdenocarcinomaUndifferentiated Carcinoma of OvaryCervical Cancer+3 more
PX Biosolutions 15
Testing effectiveness (Phase 2)Looking for participantsNCT06319963
What this trial is testing

Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

Who this might be right for
HPV-Related Cervical CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Theravectys S.A. 72
Testing effectiveness (Phase 2)Active Not RecruitingNCT05232851
What this trial is testing

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related CarcinomaLocally Advanced Oropharyngeal Carcinoma+2 more
Mayo Clinic 20
Large-scale testing (Phase 3)Active Not RecruitingNCT06790966
What this trial is testing

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Recurrent Head and Neck CancerMetastatic Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+2 more
PDS Biotechnology Corp. 252
Testing effectiveness (Phase 2)Study completedNCT00091130
What this trial is testing

SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells

Who this might be right for
Atypical Squamous Cells of Undetermined SignificanceCervical CancerHigh-grade Squamous Intraepithelial Lesion+1 more
National Cancer Institute (NCI) 139
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07418034
What this trial is testing

A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED)

Who this might be right for
Head and Neck CancerHead and Neck Squamous Cell CancerHead and Neck Squamous Cell Carcinoma+11 more
University of Maryland, Baltimore 132
Early research (Phase 1)Study completedNCT02821494
What this trial is testing

Hespecta Vaccination in HPV+ Tumors or Malignant Lesions

Who this might be right for
Tumors or Premalignant Lesions
Leiden University 25
Testing effectiveness (Phase 2)Looking for participantsNCT05280457
What this trial is testing

HPV 16-positive and/or HPV 18-positive Recurrent and/or For Patients With Metastatic Head and Neck Cancer to Evaluate GX-188E DNA Vaccination, GX-I7 and Nivolumab Combination Therapy

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Yonsei University 21
Testing effectiveness (Phase 2)Study completedNCT03603808
What this trial is testing

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

Who this might be right for
Anal Intraepithelial NeoplasiaHigh Grade Squamous Intraepithelial NeoplasiaHIV Positivity+2 more
AIDS Malignancy Consortium 35
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