Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Hypercapnic Exacerbation COPD”

30 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 30 results

Not applicableStudy completedNCT03443479
What this trial is testing

Comparison of High-flow Oxygen vs. BiPAP in Type II (Hypercapnic) Respiratory Failure

Who this might be right for
Respiratory FailureRespiratory InsufficiencyRespiratory Tract Diseases+4 more
Hôpital de Verdun 324
Not applicableUnknownNCT03990155
What this trial is testing

Extra-Corporeal Carbon Dioxide Removal in Exacerbations of Chronic Obstructive Pulmonary Disease

Who this might be right for
Respiratory Failure With Hypercapnia
Policlinico Hospital 40
Not applicableUnknownNCT03759457
What this trial is testing

High Flow Nasal Cannula and Hypercapnia

Who this might be right for
COPD
IRCCS Azienda Ospedaliero-Universitaria di Bologna 50
Not applicableUnknownNCT06212180
What this trial is testing

Comfort of Patients Under Non Invasive Ventilation According to the Mask

Who this might be right for
COPD ExacerbationHypercapniaHypoventilation Obesity Syndrome+1 more
Assistance Publique - Hôpitaux de Paris 80
Not applicableLooking for participantsNCT06114667
What this trial is testing

Nasal High Flow Versus Non-invasive Ventilation for Early Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Hypercapnic Acidosis

Who this might be right for
Acute Exacerbation of Chronic Obstructive Pulmonary DiseaseHypercapnic AcidosisRespiratory Failure With Hypercapnia
University Hospital, Montpellier 174
Post-approval studies (Phase 4)UnknownNCT01513655
What this trial is testing

Home Non Invasive Ventilation (NIV) Treatment for COPD-patients After a NIV-treated Exacerbation

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAcute Exacerbation of Chronic Obstructive Airways DiseaseChronic Hypercapnic Respiratory Failure
University Hospital, Gentofte, Copenhagen 150
Not applicableWithdrawnNCT01174316
What this trial is testing

Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Acute Exacerbation of Respiratory Failure

Who this might be right for
Respiratory FailureNeuromuscular DiseaseChest Wall Disorder+2 more
ResMed
Not applicableLooking for participantsNCT07065799
What this trial is testing

Respiratory Strategies in COPD Patients With Persistent Hypercapnia Following Exacerbation

Who this might be right for
COPDHypercapniaExacerbation Copd
IRCCS Azienda Ospedaliero-Universitaria di Bologna 31
Not applicableLooking for participantsNCT04136717
What this trial is testing

Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery

Who this might be right for
COPD ExacerbationOxygen ToxicityAbdominal Obesity+1 more
François Lellouche 10
Large-scale testing (Phase 3)Study completedNCT00990132
What this trial is testing

Home Mechanical Ventilation vs Home Oxygen Therapy in COPD

Who this might be right for
Chronic Obstructive Pulmonary Disease
Patrick Murphy 116
Not applicableStudy completedNCT04109560
What this trial is testing

HFNC and Acute Hypercapnic Respiratory Failure

Who this might be right for
High Flow Oxygen TherapyAcute Hypercapnic Respiratory FailureCOPD Exacerbation
Argentinian Intensive Care Society 40
Not applicableLooking for participantsNCT05829083
What this trial is testing

DUET Versus Standard Interface for Hypercapnic COPD Patients

Who this might be right for
COPD ExacerbationHypercapniaCOPD
Larissa University Hospital 50
Large-scale testing (Phase 3)Looking for participantsNCT07047092
What this trial is testing

Non-invasive Ventilation or CPAP in OSA-COPD Following Admission for an Acute Hypercapnic Respiratory Failure

Who this might be right for
Chronic Obstructive Pulmonary Disease ExacerbationObstructive Sleep Apnea Exacerbation
Assistance Publique - Hôpitaux de Paris 386
Not applicableUnknownNCT01791335
What this trial is testing

NIV and Glottis-diaphragm Synchrony

Who this might be right for
Noninvasive VentilationNAVA CatheterHypercapnic Exacerbation COPD
University Medical Center Nijmegen 10
Not applicableUnknownNCT04640948
What this trial is testing

High VS Low Flow Nasal O2 for Acute Hypercapnic Respiratory Failure

Who this might be right for
Acute Hypercapnic Respiratory FailureAcute Exacerbation of COPD
Belfast Health and Social Care Trust 82
Not applicableNot Yet RecruitingNCT07785375
What this trial is testing

Extracorporeal Carbon Dioxide Removal Plus Noninvasive Ventilation in Patients With COPD Not Eligible for Intubation

Who this might be right for
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Hospital del Mar Research Institute (IMIM) 14
Not applicableLooking for participantsNCT03033251
What this trial is testing

High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary Disease

Who this might be right for
Exacerbation CopdAcute Respiratory DistressAcute Hypercapnic Respiratory Failure
Unity Health Toronto 30
Not applicableNot Yet RecruitingNCT07751003
What this trial is testing

Remote Intervention Versus Routine Monitoring in COPD Patients With Chronic Hypercapnia Receiving Home Non-invasive Respiratory Support

Who this might be right for
COPD (Chronic Obstructive Pulmonary Disease)Acute Exacerbation of COPDHypercapnia
Sir Run Run Shaw Hospital 236
Post-approval studies (Phase 4)UnknownNCT03981081
What this trial is testing

Prednisone Reduction in ICU Patients With COPD Exacerbation

Who this might be right for
Copd Exacerbation AcuteMechanical Ventilation
Hôpital Universitaire Fattouma Bourguiba 192
Not applicableWithdrawnNCT07791992
What this trial is testing

Combination of High-flow Nasal Oxygen (Optiflow) and Vibrating Membrane Nebuliser (Aerogen) in the Pre-hospital Setting - Before/After Study

Who this might be right for
HypercapniaAsthma ExacerbationCOPD Exacerbation
Centre Hospitalier Sud Francilien
Next Page