Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Hypercholesterolemia, Autosomal Dominant”

294 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 294 results

Large-scale testing (Phase 3)Enrolling By InvitationNCT07102511
What this trial is testing

Study to Evaluate the Efficacy and Safety of Lerodalcibep in Children 6 to 17 Years, With Heterozygous FH

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
LIB Therapeutics LLC 150
Very early researchLooking for participantsNCT06458010
What this trial is testing

Clinical Exploration Trial of YOLT-101 in the Treatment of Familial Hypercholesterolemia (FH)

Who this might be right for
Familial Hypercholesterolemia
RenJi Hospital 20
Large-scale testing (Phase 3)Study completedNCT02107898
What this trial is testing

Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)

Who this might be right for
Hypercholesterolemia
Sanofi 216
Not applicableEnded earlyNCT02345421
What this trial is testing

Identify and Characterize LAL-D Patients in High-risk Populations

Who this might be right for
Lysosomal Acid Lipase Deficiency
Alexion Pharmaceuticals, Inc. 640
Not applicableLooking for participantsNCT06439654
What this trial is testing

Atlantic Lipid Lowering Treatment Optimization Program

Who this might be right for
Familial HypercholesterolemiaLipoprotein Types--Lp System Lp(A) HyperlipoproteinemiaApolipoprotein B 100, Familial Defective+2 more
Atlantic Health System 250
Large-scale testing (Phase 3)Study completedNCT02585895
What this trial is testing

Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment

Who this might be right for
Hypercholesterolemia
Amgen 39
Testing effectiveness (Phase 2)Study completedNCT04173793
What this trial is testing

PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Akeso 109
Not applicableUnknownNCT02489253
What this trial is testing

Atherosclerosis in Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
University College, London 100
Large-scale testing (Phase 3)Study completedNCT00867165
What this trial is testing

Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)

Who this might be right for
Primary Hypercholesterolemia
Organon and Co 138
Large-scale testing (Phase 3)Not Yet RecruitingNCT07473843
What this trial is testing

Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 12
Testing effectiveness (Phase 2)Study completedNCT01604824
What this trial is testing

Alirocumab in Participants With Autosomal Dominant Hypercholesterolemia (ADH) and Gain-of-Function Mutations (GOFm) of the Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Gene or Loss-of-Function Mutations (LOFm) of the Apolipoprotein (Apo) B Gene

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 23
Testing effectiveness (Phase 2)Looking for participantsNCT04941599
What this trial is testing

2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)

Who this might be right for
Familial Hypercholesterolemia
Vanderbilt University Medical Center 72
Not applicableWithdrawnNCT02399852
What this trial is testing

Effects of Lomitapide on Carotid and Aortic Atherosclerosis

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc.
Large-scale testing (Phase 3)Study completedNCT04034485
What this trial is testing

Phase 3 Study to Evaluate the Efficacy and Safety of LIB003 With Evolocumab in HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
LIB Therapeutics LLC 65
Large-scale testing (Phase 3)Study completedNCT02226198
What this trial is testing

Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 20
Not applicableStudy completedNCT06389825
What this trial is testing

Unravelling the Impact of Diet on Cardiovascular Health in Treated Heterozygous Familial Hypercholesterolemia.

Who this might be right for
Familial HypercholesterolemiaNutrition, HealthyCholesterol, Elevated
Laval University 11
Not applicableStudy completedNCT07023445
What this trial is testing

Patterns of Inclisiran Use in the Real World: An Analysis of US Databases

Who this might be right for
Atherosclerotic Cardiovascular DiseaseFamilial Hypercholesterolemia
Novartis Pharmaceuticals 37,688
Very early researchUnknownNCT06461702
What this trial is testing

Clinical Exploration Trial of YOLT-101 in the Treatment of Familial Hypercholesterolemia (FH)

Who this might be right for
Familial Hypercholesterolemia
The First Affiliated Hospital of Bengbu Medical University 13
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Large-scale testing (Phase 3)Study completedNCT01524289
What this trial is testing

Study to Assess the Tolerability and Efficacy of Anacetrapib (MK-0859) Co-Administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)

Who this might be right for
Hyperlipoproteinemia Type IIHypercholesterolemia, Familial
Merck Sharp & Dohme LLC 306
Next Page