Testing effectiveness (Phase 2)Study completedNCT03944577What this trial is testingImpact of Evolocumab in Cardiac Transplant Patients With CAVWho this might be right forHeart Transplant University of Nebraska 26
Large-scale testing (Phase 3)Study completedNCT00136981What this trial is testingCarotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.Who this might be right forHypercholesterolemia, FamilialHyperlipidemia Pfizer 800
Early research (Phase 1)Study completedNCT07216131What this trial is testingInvestigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 YearsWho this might be right forHealthy Participants AstraZeneca 14
Large-scale testing (Phase 3)Study completedNCT01968980What this trial is testingA 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial HypercholesterolemiaWho this might be right forHeterozygous Familial Hypercholesterolemia Pfizer 370
Post-approval studies (Phase 4)Study completedNCT02938949What this trial is testingAlirocumab in Patients With Acute Myocardial InfarctionWho this might be right forMyocardial InfarctionHypercholesterolemia Virginia Commonwealth University 20
Early research (Phase 1)Study completedNCT01979601What this trial is testingSafety, Tolerability, PK and PD of LGT209 in Healthy Volunteers and Patients With HypercholesterolemiaWho this might be right forHypercholesterolemia Novartis Pharmaceuticals 74
Large-scale testing (Phase 3)WithdrawnNCT02765841What this trial is testingEvaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering TherapyWho this might be right forHomozygous Familial Hypercholesterolemia Aegerion Pharmaceuticals, Inc.
Large-scale testing (Phase 3)Study completedNCT05142722What this trial is testingRandomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying TherapiesWho this might be right forDyslipidemiasHigh CholesterolHypercholesterolemia+2 more NewAmsterdam Pharma 2,530
Large-scale testing (Phase 3)Study completedNCT02833844What this trial is testingSafety, Tolerability and Efficacy on Low Density Lipoprotein Cholesterol (LDL-C) of Evolocumab in Participants With Human Immunodeficiency Virus (HIV) and Hyperlipidemia/Mixed DyslipidemiaWho this might be right forSubjects With Hyperlipidemia, Dyslipidemia and HIV Infection Amgen 467
Large-scale testing (Phase 3)Study completedNCT04034485What this trial is testingPhase 3 Study to Evaluate the Efficacy and Safety of LIB003 With Evolocumab in HoFHWho this might be right forHomozygous Familial Hypercholesterolemia LIB Therapeutics LLC 65
Large-scale testing (Phase 3)Study completedNCT04031742What this trial is testingEvaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial HypercholesterolemiaWho this might be right forHomozygous Familial Hypercholesterolemia Innovent Biologics (Suzhou) Co. Ltd. 18
Large-scale testing (Phase 3)Study completedNCT05952869What this trial is testingEnlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017) CORALreef HeFHWho this might be right forHypercholesterolemiaFamilial Hypercholesterolemia Merck Sharp & Dohme LLC 303
Large-scale testing (Phase 3)Study completedNCT05952856What this trial is testingEnlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef LipidsWho this might be right forHypercholesterolemiaFamilial Hypercholesterolemia Merck Sharp & Dohme LLC 2,912
Large-scale testing (Phase 3)Study completedNCT00134485What this trial is testingStudy To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial HypercholerolemiaWho this might be right forHypercholesterolemia, FamilialHyperlipidemia Pfizer 400
Not applicableActive Not RecruitingNCT04656028What this trial is testingGenetic Testing and Motivational Counseling for FHWho this might be right forHypercholesterolemia, FamilialHypercholesterolemia, Familial, 1Hypercholesterolemia, Familial, 2+23 more National Medical Research Center for Therapy and Preventive Medicine 180
Large-scale testing (Phase 3)Study completedNCT01475825What this trial is testingThe Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein CholesterolWho this might be right forHypercholesterolemiaHeterozygous Familial Kastle Therapeutics, LLC 309
Large-scale testing (Phase 3)Study completedNCT02729025What this trial is testingEffects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in Patients With Elevated Lipoprotein(a) (Lp(a))Who this might be right forSubjects With Hyperlipidemia, Dyslipidemia Amgen 129
Large-scale testing (Phase 3)Looking for participantsNCT07058077What this trial is testingEnlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)Who this might be right forHeterozygous Familial Hypercholesterolemia (HeFH) Merck Sharp & Dohme LLC 153
Not applicableLooking for participantsNCT04485871What this trial is testingTargeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty AcidsWho this might be right forType 2 DiabetesInflammationInsulin Sensitivity/Resistance+1 more Institut de Recherches Cliniques de Montreal 48
Testing effectiveness (Phase 2)Study completedNCT01375751What this trial is testingReduction of Low-Density Lipoprotein Cholesterol (LDL-C) With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder StudyWho this might be right forHypercholesterolemia, Familial Amgen 168