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Results for “Hypercholesterolemia, Autosomal Dominant, 3”

38 trials

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Showing 20 of 38 results

Large-scale testing (Phase 3)Study completedNCT00867165
What this trial is testing

Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)

Who this might be right for
Primary Hypercholesterolemia
Organon and Co 138
Large-scale testing (Phase 3)Study completedNCT00136981
What this trial is testing

Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.

Who this might be right for
Hypercholesterolemia, FamilialHyperlipidemia
Pfizer 800
Large-scale testing (Phase 3)Study completedNCT06005597
What this trial is testing

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHypercholesterolemiaFamilial Hypercholesterolemia+2 more
NewAmsterdam Pharma 407
Large-scale testing (Phase 3)Study completedNCT02729025
What this trial is testing

Effects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in Patients With Elevated Lipoprotein(a) (Lp(a))

Who this might be right for
Subjects With Hyperlipidemia, Dyslipidemia
Amgen 129
Testing effectiveness (Phase 2)Study completedNCT01604824
What this trial is testing

Alirocumab in Participants With Autosomal Dominant Hypercholesterolemia (ADH) and Gain-of-Function Mutations (GOFm) of the Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Gene or Loss-of-Function Mutations (LOFm) of the Apolipoprotein (Apo) B Gene

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 23
Large-scale testing (Phase 3)Looking for participantsNCT07058077
What this trial is testing

Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC 153
Testing effectiveness (Phase 2)Study completedNCT01375764
What this trial is testing

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

Who this might be right for
Hyperlipidemia
Amgen 160
Large-scale testing (Phase 3)Not Yet RecruitingNCT06712771
What this trial is testing

Clinical Trial to Evaluate the Efficacy and Safety of VSA003 in Chinese HoFH Patients

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
Visirna Therapeutics HK Limited 45
Large-scale testing (Phase 3)Study completedNCT05952856
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 2,912
Large-scale testing (Phase 3)Study completedNCT05142722
What this trial is testing

Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia+2 more
NewAmsterdam Pharma 2,530
Testing effectiveness (Phase 2)Study completedNCT03944577
What this trial is testing

Impact of Evolocumab in Cardiac Transplant Patients With CAV

Who this might be right for
Heart Transplant
University of Nebraska 26
Large-scale testing (Phase 3)Study completedNCT01968980
What this trial is testing

A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Pfizer 370
Large-scale testing (Phase 3)Study completedNCT02833844
What this trial is testing

Safety, Tolerability and Efficacy on Low Density Lipoprotein Cholesterol (LDL-C) of Evolocumab in Participants With Human Immunodeficiency Virus (HIV) and Hyperlipidemia/Mixed Dyslipidemia

Who this might be right for
Subjects With Hyperlipidemia, Dyslipidemia and HIV Infection
Amgen 467
Not applicableStudy completedNCT02674659
What this trial is testing

The Effect of Resistance Training on Proprotein Subtilisin Convertase Kexin 9 Level After Coronary Bypass Surgery

Who this might be right for
Coronary Artery Disease
National Cardiovascular Center Harapan Kita Hospital Indonesia 87
Large-scale testing (Phase 3)Study completedNCT00134485
What this trial is testing

Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia

Who this might be right for
Hypercholesterolemia, FamilialHyperlipidemia
Pfizer 400
Testing effectiveness (Phase 2)Study completedNCT01375777
What this trial is testing

Monoclonal Antibody Against PCSK9 to Reduce Elevated Low-density Lipoprotein Cholesterol (LDL-C) in Adults Currently Not Receiving Drug Therapy for Easing Lipid Levels

Who this might be right for
Hyperlipidemia
Amgen 411
Not applicableActive Not RecruitingNCT04656028
What this trial is testing

Genetic Testing and Motivational Counseling for FH

Who this might be right for
Hypercholesterolemia, FamilialHypercholesterolemia, Familial, 1Hypercholesterolemia, Familial, 2+23 more
National Medical Research Center for Therapy and Preventive Medicine 180
Large-scale testing (Phase 3)Study completedNCT05952869
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH)

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 303
Testing effectiveness (Phase 2)Study completedNCT01375751
What this trial is testing

Reduction of Low-Density Lipoprotein Cholesterol (LDL-C) With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study

Who this might be right for
Hypercholesterolemia, Familial
Amgen 168
Not applicableLooking for participantsNCT04485871
What this trial is testing

Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids

Who this might be right for
Type 2 DiabetesInflammationInsulin Sensitivity/Resistance+1 more
Institut de Recherches Cliniques de Montreal 48
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