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Results for “Hypercholesterolemia, Autosomal Dominant”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT01623115
What this trial is testing

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Who this might be right for
Hypercholesterolemia
Sanofi 486
Large-scale testing (Phase 3)Not Yet RecruitingNCT07450378
What this trial is testing

QLC7401 in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Qilu Pharmaceutical Co., Ltd. 120
Testing effectiveness (Phase 2)Study completedNCT02048410
What this trial is testing

Efficacy of a New Symbiotic Formulation in Children With Familial Hypercholesterolemia

Who this might be right for
DyslipidemiaFamilial Hypercholesterolemia
Federico II University 40
Early research (Phase 1)Study completedNCT03747224
What this trial is testing

Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients

Who this might be right for
DyslipidemiasFamilial HypercholesterolemiaHypertriglyceridemia
Arrowhead Pharmaceuticals 93
Large-scale testing (Phase 3)Study completedNCT05611528
What this trial is testing

Safety and Effectiveness of Evinacumab for the Treatment of Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Daniel Gaudet 10
Not applicableStudy completedNCT03253432
What this trial is testing

IN-TANDEM Familial Hypercholesterolemia Pilot Study

Who this might be right for
Familial Hypercholesterolemia
University of Pennsylvania 378
Not applicableLooking for participantsNCT05348564
What this trial is testing

Comparing Direct vs Indirect Methods for Cascade Screening

Who this might be right for
Long QT SyndromeFamilial HypercholesterolemiaEthics+1 more
University of Maryland, Baltimore 200
Not applicableStudy completedNCT00704444
What this trial is testing

A 12-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05244)

Who this might be right for
HypercholesterolemiaFamilial HypercholesterolemiaHomozygous Sitosterolemia
Organon and Co 11,332
Testing effectiveness (Phase 2)Study completedNCT01890967
What this trial is testing

LY3015014 in Participants With High Cholesterol

Who this might be right for
Hypercholesterolemia
Eli Lilly and Company 527
Not applicableStudy completedNCT05352386
What this trial is testing

Coronary and Heart Effects of Early Treatment in Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 135
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Post-approval studies (Phase 4)Study completedNCT06231459
What this trial is testing

Expression of Pro- and Anti-inflammatory Cytokines During Anti-PCSK9 in Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia, Familial
Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado 20
Post-approval studies (Phase 4)Study completedNCT02957682
What this trial is testing

Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 2,176
Large-scale testing (Phase 3)Looking for participantsNCT07421297
What this trial is testing

Evaluate the Safety, Efficacy of SYH2053 as Monotherapy in Chinese Participants With Non-familial Hypercholesterolemia or Mixed Hyperlipidemia

Who this might be right for
Non-familial Hypercholesterolemia and Mixed Hyperlipidemia
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 760
Not applicableActive Not RecruitingNCT05758779
What this trial is testing

The Danish Familial Hypercholesterolemia Organized Coronary Screening Trial

Who this might be right for
Familial HypercholesterolemiaAtherosclerosis
Odense University Hospital 100
Testing effectiveness (Phase 2)Study completedNCT01556906
What this trial is testing

Safety, Tolerability and Efficacy of Microsomal Triglyceride Protein (MTP) Inhibitor

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 6
Not applicableUnknownNCT03984149
What this trial is testing

Lipa Gene Mutation in PED-LIPIGEN (Pediatric FH Subjects)

Who this might be right for
Lysosomal Acid Lipase Deficiency
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 1,000
Early research (Phase 1)Study completedNCT01859455
What this trial is testing

Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statins

Who this might be right for
HypercholesterolemiaLDL Cholesterol
Novartis Pharmaceuticals 25
Large-scale testing (Phase 3)Study completedNCT00552097
What this trial is testing

Effect of Ezetimibe Plus Simvastatin Versus Simvastatin Alone on Atherosclerosis in the Carotid Artery (ENHANCE)(P02578)

Who this might be right for
AtherosclerosisHypercholesterolemiaHyperlipoproteinemia Type II
Organon and Co 720
Testing effectiveness (Phase 2)Study completedNCT02963311
What this trial is testing

ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
The Medicines Company 9
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