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Results for “Hypercholesterolemia, Familial”

311 trials

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Showing 20 of 311 results

Large-scale testing (Phase 3)Enrolling By InvitationNCT07102511
What this trial is testing

Study to Evaluate the Efficacy and Safety of Lerodalcibep in Children 6 to 17 Years, With Heterozygous FH

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
LIB Therapeutics LLC 150
Very early researchLooking for participantsNCT06458010
What this trial is testing

Clinical Exploration Trial of YOLT-101 in the Treatment of Familial Hypercholesterolemia (FH)

Who this might be right for
Familial Hypercholesterolemia
RenJi Hospital 20
Not applicableStudy completedNCT07090629
What this trial is testing

The Benefits of the Measureof Epicardial Adipose Tissue During Coronary Calcium Assessment of the Refine Cardiovascular Risk Assessment at Reunion Island.

Who this might be right for
High CholesterolLipodystrophy, Familial PartialDiabetes
Centre Hospitalier Universitaire de la Réunion 126
Large-scale testing (Phase 3)Study completedNCT02107898
What this trial is testing

Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)

Who this might be right for
Hypercholesterolemia
Sanofi 216
Not applicableEnded earlyNCT02345421
What this trial is testing

Identify and Characterize LAL-D Patients in High-risk Populations

Who this might be right for
Lysosomal Acid Lipase Deficiency
Alexion Pharmaceuticals, Inc. 640
Not applicableLooking for participantsNCT06439654
What this trial is testing

Atlantic Lipid Lowering Treatment Optimization Program

Who this might be right for
Familial HypercholesterolemiaLipoprotein Types--Lp System Lp(A) HyperlipoproteinemiaApolipoprotein B 100, Familial Defective+2 more
Atlantic Health System 250
Large-scale testing (Phase 3)Study completedNCT02585895
What this trial is testing

Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment

Who this might be right for
Hypercholesterolemia
Amgen 39
Testing effectiveness (Phase 2)Study completedNCT04173793
What this trial is testing

PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Akeso 109
Not applicableUnknownNCT02489253
What this trial is testing

Atherosclerosis in Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
University College, London 100
Large-scale testing (Phase 3)Study completedNCT00867165
What this trial is testing

Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)

Who this might be right for
Primary Hypercholesterolemia
Organon and Co 138
Large-scale testing (Phase 3)Not Yet RecruitingNCT07473843
What this trial is testing

Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 12
Not applicableStudy completedNCT00005313
What this trial is testing

Human Lipoprotein Pathophysiology - Subproject: Genetics of Familial Combined Hyperlipidemia

Who this might be right for
AtherosclerosisCardiovascular DiseasesHeart Diseases+2 more
University of Washington 450
Testing effectiveness (Phase 2)Looking for participantsNCT04941599
What this trial is testing

2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)

Who this might be right for
Familial Hypercholesterolemia
Vanderbilt University Medical Center 72
Not applicableWithdrawnNCT02399852
What this trial is testing

Effects of Lomitapide on Carotid and Aortic Atherosclerosis

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc.
Large-scale testing (Phase 3)Study completedNCT04034485
What this trial is testing

Phase 3 Study to Evaluate the Efficacy and Safety of LIB003 With Evolocumab in HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
LIB Therapeutics LLC 65
Large-scale testing (Phase 3)Study completedNCT02226198
What this trial is testing

Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 20
Not applicableStudy completedNCT06389825
What this trial is testing

Unravelling the Impact of Diet on Cardiovascular Health in Treated Heterozygous Familial Hypercholesterolemia.

Who this might be right for
Familial HypercholesterolemiaNutrition, HealthyCholesterol, Elevated
Laval University 11
Not applicableStudy completedNCT07023445
What this trial is testing

Patterns of Inclisiran Use in the Real World: An Analysis of US Databases

Who this might be right for
Atherosclerotic Cardiovascular DiseaseFamilial Hypercholesterolemia
Novartis Pharmaceuticals 37,688
Very early researchUnknownNCT06461702
What this trial is testing

Clinical Exploration Trial of YOLT-101 in the Treatment of Familial Hypercholesterolemia (FH)

Who this might be right for
Familial Hypercholesterolemia
The First Affiliated Hospital of Bengbu Medical University 13
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
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