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Results for “Hypercholesterolemia, Familial, 2”

32 trials

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Showing 20 of 32 results

Testing effectiveness (Phase 2)Study completedNCT03038022
What this trial is testing

Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Madrigal Pharmaceuticals, Inc. 116
Testing effectiveness (Phase 2)Ended earlyNCT05217667
What this trial is testing

Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 18
Large-scale testing (Phase 3)Study completedNCT01475825
What this trial is testing

The Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol

Who this might be right for
HypercholesterolemiaHeterozygous Familial
Kastle Therapeutics, LLC 309
Not applicableStudy completedNCT02317003
What this trial is testing

Physical Exercise Prescription With PEdometeR in General Practice for Patients With Cardiovascular Risk Factors - PEPPER

Who this might be right for
Sedentary LifestyleCardiovascular DiseasesHypertension+2 more
University Hospital, Angers 126
Large-scale testing (Phase 3)Looking for participantsNCT06597019
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07839936
What this trial is testing

VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease

Who this might be right for
AtherosclerosisCardiovascular DiseaseHypercholesterolemia
Verve Therapeutics, Inc. 175
Testing effectiveness (Phase 2)Study completedNCT02722408
What this trial is testing

Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)

Who this might be right for
Hypercholesteremia
NeuroBo Pharmaceuticals Inc. 8
Early research (Phase 1)Study completedNCT00692250
What this trial is testing

Assess Any Potential Interaction Between Colesevelam and Ciclosporin in Healthy Volunteers

Who this might be right for
Healthy
Genzyme, a Sanofi Company 14
Large-scale testing (Phase 3)Study completedNCT04659863
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 13
Large-scale testing (Phase 3)Study completedNCT04652726
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals 141
Testing effectiveness (Phase 2)Study completedNCT01604824
What this trial is testing

Alirocumab in Participants With Autosomal Dominant Hypercholesterolemia (ADH) and Gain-of-Function Mutations (GOFm) of the Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Gene or Loss-of-Function Mutations (LOFm) of the Apolipoprotein (Apo) B Gene

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 23
Testing effectiveness (Phase 2)WithdrawnNCT03455777
What this trial is testing

Study of AKCEA-ANGPTL3-LRX (ISIS 703802) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Akcea Therapeutics
Large-scale testing (Phase 3)Looking for participantsNCT07058077
What this trial is testing

Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC 153
Testing effectiveness (Phase 2)Looking for participantsNCT04941599
What this trial is testing

2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)

Who this might be right for
Familial Hypercholesterolemia
Vanderbilt University Medical Center 72
Not applicableStudy completedNCT02286596
What this trial is testing

Comparisons of Two Low-density Lipoprotein Apheresis Systems in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Laval University 9
Testing effectiveness (Phase 2)Study completedNCT01279590
What this trial is testing

Study of the Safety and Tolerability Associated With PPD10558 Versus Atorvastatin in Patients Previously Intolerant to Statins Due to Statin-associated Myalgia (SAM)

Who this might be right for
MyalgiaHypercholesterolemiaHyperlipidemia
Furiex Pharmaceuticals, Inc 282
Large-scale testing (Phase 3)Study completedNCT03851705
What this trial is testing

Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 56
Large-scale testing (Phase 3)Study completedNCT01078675
What this trial is testing

Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia

Who this might be right for
Familial Hypercholesterolaemia
AstraZeneca 315
Testing effectiveness (Phase 2)Study completedNCT00941603
What this trial is testing

Phase 2 Dose-Ranging Efficacy and Safety Trial of SCH 900271 in Participants With Primary Hypercholesterolemia or Mixed Hyperlipidemia (P05675)

Who this might be right for
Primary HypercholesterolemiaMixed Hyperlipidemia
Merck Sharp & Dohme LLC 619
Post-approval studies (Phase 4)Study completedNCT00473655
What this trial is testing

Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic Patients

Who this might be right for
HypertriglyceridemiaHyperlipoproteinemia Type IVHyperlipoproteinemia Type V+2 more
AstraZeneca 334
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