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Results for “Hypercholesterolemia, Familial, 2”

31 trials

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Showing 20 of 31 results

Testing effectiveness (Phase 2)Study completedNCT01279590
What this trial is testing

Study of the Safety and Tolerability Associated With PPD10558 Versus Atorvastatin in Patients Previously Intolerant to Statins Due to Statin-associated Myalgia (SAM)

Who this might be right for
MyalgiaHypercholesterolemiaHyperlipidemia
Furiex Pharmaceuticals, Inc 282
Large-scale testing (Phase 3)Looking for participantsNCT06597006
What this trial is testing

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 9
Post-approval studies (Phase 4)Study completedNCT00473655
What this trial is testing

Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic Patients

Who this might be right for
HypertriglyceridemiaHyperlipoproteinemia Type IVHyperlipoproteinemia Type V+2 more
AstraZeneca 334
Testing effectiveness (Phase 2)Study completedNCT00280995
What this trial is testing

Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Who this might be right for
Hypercholesterolemia, Familial
Kastle Therapeutics, LLC 12
Testing effectiveness (Phase 2)WithdrawnNCT03455777
What this trial is testing

Study of AKCEA-ANGPTL3-LRX (ISIS 703802) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Akcea Therapeutics
Testing effectiveness (Phase 2)Study completedNCT01604824
What this trial is testing

Alirocumab in Participants With Autosomal Dominant Hypercholesterolemia (ADH) and Gain-of-Function Mutations (GOFm) of the Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Gene or Loss-of-Function Mutations (LOFm) of the Apolipoprotein (Apo) B Gene

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 23
Testing effectiveness (Phase 2)Study completedNCT02722408
What this trial is testing

Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)

Who this might be right for
Hypercholesteremia
NeuroBo Pharmaceuticals Inc. 8
Not applicableWithdrawnNCT03756779
What this trial is testing

Cross-over Pilot Study of Blood Cholesterol Response to Dietary Saturated Fat in Patients With Autosomal Dominant Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
University of Texas Southwestern Medical Center
Testing effectiveness (Phase 2)Study completedNCT00941603
What this trial is testing

Phase 2 Dose-Ranging Efficacy and Safety Trial of SCH 900271 in Participants With Primary Hypercholesterolemia or Mixed Hyperlipidemia (P05675)

Who this might be right for
Primary HypercholesterolemiaMixed Hyperlipidemia
Merck Sharp & Dohme LLC 619
Large-scale testing (Phase 3)Study completedNCT01588496
What this trial is testing

Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities

Who this might be right for
Homozygous Familial Hypercholesterolemia
Amgen 58
Testing effectiveness (Phase 2)Study completedNCT00281008
What this trial is testing

Study of ISIS 301012 (Mipomersen) in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Who this might be right for
Hypercholesterolemia, Familial
Kastle Therapeutics, LLC 44
Not applicableLooking for participantsNCT07086989
What this trial is testing

Cardiovascular Risk in Children With Chronic Conditions Study

Who this might be right for
Kidney TransplantFamilial HypercholesterolaemiaType 1 Diabetes Mellitus (T1DM)+22 more
Semmelweis University 300
Not applicableStudy completedNCT05218005
What this trial is testing

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia

Who this might be right for
Familial HypercholesterolemiaFamilial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein BFamilial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation+5 more
University of British Columbia 140
Large-scale testing (Phase 3)Study completedNCT04652726
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals 141
Large-scale testing (Phase 3)Study completedNCT04659863
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 13
Large-scale testing (Phase 3)Study completedNCT01475825
What this trial is testing

The Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol

Who this might be right for
HypercholesterolemiaHeterozygous Familial
Kastle Therapeutics, LLC 309
Testing effectiveness (Phase 2)Looking for participantsNCT04941599
What this trial is testing

2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)

Who this might be right for
Familial Hypercholesterolemia
Vanderbilt University Medical Center 72
Early research (Phase 1)Study completedNCT00692250
What this trial is testing

Assess Any Potential Interaction Between Colesevelam and Ciclosporin in Healthy Volunteers

Who this might be right for
Healthy
Genzyme, a Sanofi Company 14
Not applicableStudy completedNCT02286596
What this trial is testing

Comparisons of Two Low-density Lipoprotein Apheresis Systems in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Laval University 9
Testing effectiveness (Phase 2)Study completedNCT01576484
What this trial is testing

Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 58
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