Not applicableNo Longer AvailableNCT04498871What this trial is testingMAP to Provide Access to Nilotinib, for Patients With HESWho this might be right forHypereosinophilic Syndrome (HES) Novartis Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT00154388What this trial is testingPhase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare DiseasesWho this might be right forLife Threatening Diseases Novartis Pharmaceuticals 185
Large-scale testing (Phase 3)Study completedNCT02836496What this trial is testingEfficacy and Safety Study of Mepolizumab in Subjects With Severe Hypereosinophilic Syndrome (HES)Who this might be right forHypereosinophilic Syndrome GlaxoSmithKline 108
Not applicableStudy completedNCT00255957What this trial is testingInfluence of Hydroxyehtyl Starch (HES) on Hemorehology, Coagulation and Elimination KineticsWho this might be right forStroke Patients Presenting Within 24 Hrs of Onset of Symptoms Nizam's Institute of Medical Sciences University, India 20
Large-scale testing (Phase 3)Study completedNCT03306043What this trial is testingA Multi-center, Open-label Extension, Safety Study of Mepolizumab in Subjects With Hypereosinophilic Syndrome (HES) From Study 200622Who this might be right forHypereosinophilic Syndrome GlaxoSmithKline 102
Testing effectiveness (Phase 2)UnknownNCT00276926What this trial is testingStudy of STI571 in the Treatment of Patients With Idiopathic Hypereosinophilic Syndrome (HES) and Eosinophilic LeukemiasWho this might be right forHypereosinophilic SyndromeChronic Eosinophilic Leukemia (CEL)Myeloproliferative Disorders University of Bologna
Not applicableStudy completedNCT06172751What this trial is testingTrinetX Study of Hypereosinophilic Syndrome (HES) Without an Identifiable Non-haematological Secondary CauseWho this might be right forHypereosinophilic Syndrome (HES) AstraZeneca 250
Not applicableNot Yet RecruitingNCT06911775What this trial is testingEosinophil Subpopulations in Eosinophilic-associated DiseasesWho this might be right forEosinophilic AsthmaEosinophilic Granulomatosis With Polyangiitis (EGPA)Hypereosinophilic Syndrome (HES) University of Florence 160
Post-approval studies (Phase 4)Study completedNCT01524536What this trial is testingSteroid Treatment for Hypereosinophilic SyndromeWho this might be right forEosinophiliaHypereosinophilic SyndromeLeukocyte Disorder+1 more National Institute of Allergy and Infectious Diseases (NIAID) 26
Testing effectiveness (Phase 2)Study completedNCT00255346What this trial is testingDasatinib as Therapy for Myeloproliferative Disorders (MPDs)Who this might be right forAcute Myeloid LeukemiaMyelodysplastic SyndromesAgnogenic Myeloid Metaplasia+5 more M.D. Anderson Cancer Center 68
Testing effectiveness (Phase 2)Ended earlyNCT00171860What this trial is testingDetermine the Safety and Efficacy of Imatinib Mesylate in Patients With Idiopathic Hypereosinophilic SyndromeWho this might be right forHypereosinophilic Syndrome Novartis Pharmaceuticals 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT03801434What this trial is testingRuxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic DisordersWho this might be right forBCR-JAK2 Fusion Protein ExpressionBlasts 20 Percent or Less of Peripheral Blood White CellsBlasts More Than 5 Percent of Bone Marrow Nucleated Cells+9 more Stanford University 8
Testing effectiveness (Phase 2)Study completedNCT00787384What this trial is testingEfficacy of Imatinib Mesylate in Hypereosinophilic SyndromesWho this might be right forHypereosinophilic SyndromeChronic Eosinophilic LeukemiaChronic Idiopathic Hypereosinophilia Northern Italy Leukemia Group 25
Large-scale testing (Phase 3)UnknownNCT02130882What this trial is testingStudy to Evaluate Safety and Efficacy of Benralizumab in Subjects With Hypereosinophilic SyndromeWho this might be right forRespiratory System AgentsAnti-Asthmatic AgentsHematologic Diseases+2 more National Institute of Allergy and Infectious Diseases (NIAID) 20
Testing effectiveness (Phase 2)Study completedNCT00483067What this trial is testing2-Chlorodeoxyadenosine and Cytarabine in Patients With Idiopathic Hypereosinophilic Syndrome (HES)Who this might be right forLeukemia M.D. Anderson Cancer Center 13
Testing effectiveness (Phase 2)Study completedNCT00109707What this trial is testingOral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic MalignanciesWho this might be right forChronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)Hypereosinophilic Syndrome+1 more Novartis Pharmaceuticals 507
Large-scale testing (Phase 3)Study completedNCT00086658What this trial is testingIntravenous Mepolizumab In Subjects With Hypereosinophilic Syndromes (HES)Who this might be right forHypereosinophiliaHypereosinophilic Syndrome GlaxoSmithKline 86
Early research (Phase 1)Ended earlyNCT01066468What this trial is testingGlivec/Gleevec Pediatric (Age 1 to Less Than 4) PK Study in CML, Ph+ ALL Patients and Other Glivec/Gleevec® Indicated Hematological Disorders.Who this might be right forChronic Myeloid Leukemia (CML)Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)Other Glivec/Gleevec Indicated Hematological Disorders (HES, CEL, MDS/ MPN) Novartis Pharmaceuticals 3
Large-scale testing (Phase 3)Looking for participantsNCT07444567What this trial is testingRoll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued TreatmentWho this might be right forAsthmaEosinophilic Granulomatosis With Polyangiitis (EGPA)Hypereosinophilic Syndrome (HES) AstraZeneca 230
Not applicableLooking for participantsNCT07275190What this trial is testingThe Use of Machine Learning Techniques for the Differential Diagnosis Between Eosinophilic Granulomatosis With Polyangiitis and Hypereosinophilic SyndromeWho this might be right forEGPA - Eosinophilic Granulomatosis With PolyangiitisHES - Hypereosinophilic Syndrome Fondazione IRCCS Policlinico San Matteo di Pavia 60