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Results for “Hypereosinophilic Syndrome (HES)”

26 trials

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Showing 20 of 26 results

Testing effectiveness (Phase 2)Study completedNCT00109707
What this trial is testing

Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

Who this might be right for
Chronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)Hypereosinophilic Syndrome+1 more
Novartis Pharmaceuticals 507
Not applicableNo Longer AvailableNCT00244686
What this trial is testing

This Record Contains Information About the Mepolizumab Compassionate Use (CU) Product Activities: 104317: CU and Long-Term Access Study of Mepolizumab in HES. 201956:A Long-term Access Programme for Subjects With Severe Asthma 112562: Expanded Access for Patients With Hypereosinophilic

Who this might be right for
Hypereosinophilic Syndrome
GlaxoSmithKline
Large-scale testing (Phase 3)Study completedNCT00086658
What this trial is testing

Intravenous Mepolizumab In Subjects With Hypereosinophilic Syndromes (HES)

Who this might be right for
HypereosinophiliaHypereosinophilic Syndrome
GlaxoSmithKline 86
Testing effectiveness (Phase 2)Ended earlyNCT00171860
What this trial is testing

Determine the Safety and Efficacy of Imatinib Mesylate in Patients With Idiopathic Hypereosinophilic Syndrome

Who this might be right for
Hypereosinophilic Syndrome
Novartis Pharmaceuticals 24
Large-scale testing (Phase 3)Active Not RecruitingNCT04191304
What this trial is testing

A Phase III Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES)

Who this might be right for
Hypereosinophilic Syndrome
AstraZeneca 134
Testing effectiveness (Phase 2)Study completedNCT00787384
What this trial is testing

Efficacy of Imatinib Mesylate in Hypereosinophilic Syndromes

Who this might be right for
Hypereosinophilic SyndromeChronic Eosinophilic LeukemiaChronic Idiopathic Hypereosinophilia
Northern Italy Leukemia Group 25
Large-scale testing (Phase 3)UnknownNCT02130882
What this trial is testing

Study to Evaluate Safety and Efficacy of Benralizumab in Subjects With Hypereosinophilic Syndrome

Who this might be right for
Respiratory System AgentsAnti-Asthmatic AgentsHematologic Diseases+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 20
Testing effectiveness (Phase 2)Study completedNCT00154388
What this trial is testing

Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases

Who this might be right for
Life Threatening Diseases
Novartis Pharmaceuticals 185
Not applicableStudy completedNCT06172751
What this trial is testing

TrinetX Study of Hypereosinophilic Syndrome (HES) Without an Identifiable Non-haematological Secondary Cause

Who this might be right for
Hypereosinophilic Syndrome (HES)
AstraZeneca 250
Testing effectiveness (Phase 2)Ended earlyNCT00230334
What this trial is testing

Phase II Gleevec Idiopathic Hypereosinophilic Syndrome

Who this might be right for
EosinophiliaHypereosinophilic Syndrome
Steven E. Coutre 5
Not applicableStudy completedNCT00255957
What this trial is testing

Influence of Hydroxyehtyl Starch (HES) on Hemorehology, Coagulation and Elimination Kinetics

Who this might be right for
Stroke Patients Presenting Within 24 Hrs of Onset of Symptoms
Nizam's Institute of Medical Sciences University, India 20
Not applicableNot Yet RecruitingNCT06911775
What this trial is testing

Eosinophil Subpopulations in Eosinophilic-associated Diseases

Who this might be right for
Eosinophilic AsthmaEosinophilic Granulomatosis With Polyangiitis (EGPA)Hypereosinophilic Syndrome (HES)
University of Florence 160
Large-scale testing (Phase 3)Study completedNCT03306043
What this trial is testing

A Multi-center, Open-label Extension, Safety Study of Mepolizumab in Subjects With Hypereosinophilic Syndrome (HES) From Study 200622

Who this might be right for
Hypereosinophilic Syndrome
GlaxoSmithKline 102
Post-approval studies (Phase 4)Study completedNCT01524536
What this trial is testing

Steroid Treatment for Hypereosinophilic Syndrome

Who this might be right for
EosinophiliaHypereosinophilic SyndromeLeukocyte Disorder+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 26
Testing effectiveness (Phase 2)Looking for participantsNCT03801434
What this trial is testing

Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders

Who this might be right for
BCR-JAK2 Fusion Protein ExpressionBlasts 20 Percent or Less of Peripheral Blood White CellsBlasts More Than 5 Percent of Bone Marrow Nucleated Cells+9 more
William Shomali 10
Testing effectiveness (Phase 2)Study completedNCT00483067
What this trial is testing

2-Chlorodeoxyadenosine and Cytarabine in Patients With Idiopathic Hypereosinophilic Syndrome (HES)

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 13
Not applicableLooking for participantsNCT07275190
What this trial is testing

The Use of Machine Learning Techniques for the Differential Diagnosis Between Eosinophilic Granulomatosis With Polyangiitis and Hypereosinophilic Syndrome

Who this might be right for
EGPA - Eosinophilic Granulomatosis With PolyangiitisHES - Hypereosinophilic Syndrome
Fondazione IRCCS Policlinico San Matteo di Pavia 60
Early research (Phase 1)Ended earlyNCT01066468
What this trial is testing

Glivec/Gleevec Pediatric (Age 1 to Less Than 4) PK Study in CML, Ph+ ALL Patients and Other Glivec/Gleevec® Indicated Hematological Disorders.

Who this might be right for
Chronic Myeloid Leukemia (CML)Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)Other Glivec/Gleevec Indicated Hematological Disorders (HES, CEL, MDS/ MPN)
Novartis Pharmaceuticals 3
Large-scale testing (Phase 3)Looking for participantsNCT05334368
What this trial is testing

Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial

Who this might be right for
Hypereosinophilic Syndrome
GlaxoSmithKline 123
Not applicableNo Longer AvailableNCT04498871
What this trial is testing

MAP to Provide Access to Nilotinib, for Patients With HES

Who this might be right for
Hypereosinophilic Syndrome (HES)
Novartis Pharmaceuticals
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