Not applicableStudy completedNCT04925804What this trial is testingUnraveling Genetics of HypoPhosPhatasia (HPP Genetics)Who this might be right forHypophosphatasia CENTOGENE GmbH Rostock 16
Post-approval studies (Phase 4)Study completedNCT02531867What this trial is testingPost-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in JapanWho this might be right forHypophosphatasia Alexion Pharmaceuticals, Inc. 13
Not applicableStudy completedNCT01419028What this trial is testingA Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)Who this might be right forHypophosphatasia (HPP) Alexion Pharmaceuticals, Inc. 48
Large-scale testing (Phase 3)Active Not RecruitingNCT06079359What this trial is testingPhase 3 Study of ALXN1850 in Treatment-Naïve Pediatric Participants With HPPWho this might be right forHypophosphatasia Alexion Pharmaceuticals, Inc. 30
Testing effectiveness (Phase 2)Study completedNCT01406977What this trial is testingDose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP)Who this might be right forHypophosphatasia Ultragenyx Pharmaceutical Inc 8
Not applicableStudy completedNCT02104219What this trial is testingRetrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)Who this might be right forHypophosphatasia (HPP) Alexion Pharmaceuticals, Inc. 32
Not applicableLooking for participantsNCT06574282What this trial is testingCharacteristics of Hypophosphatasia in Adult Patients in Rheumatology and Their Value in Developing an Algorithm to HPP-diagnosis - the COHIR Multi-center StudyWho this might be right forHypophosphatasia University of Bonn 720
Not applicableLooking for participantsNCT07390240What this trial is testingThe Effect of Monoallelic Variants in the ALPL Gene on the Natural Course of Hypophosphatasia in RussiaWho this might be right forHypophosphatasia AstraZeneca 55
Not applicableLooking for participantsNCT02237625What this trial is testingNatural History Study of Patients With Hypophosphatasia (HPP)Who this might be right forHypophosphatasia Duke University 200
Testing effectiveness (Phase 2)Study completedNCT01203826What this trial is testingExtension Study of Protocol ENB-006-09 - Study of Asfotase Alfa in Children With Hypophosphatasia (HPP)Who this might be right forHypophosphatasia (HPP) Alexion Pharmaceuticals, Inc. 12
Large-scale testing (Phase 3)Active Not RecruitingNCT06079372What this trial is testingPhase 3 Study of ALXN1850 in Pediatric Participants With HPP Previously Treated With Asfotase AlfaWho this might be right forHypophosphatasia Alexion Pharmaceuticals, Inc. 43
Testing effectiveness (Phase 2)Study completedNCT02456038What this trial is testingSafety and Efficacy of Asfotase Alfa in Patients With Hypophosphatasia (HPP)Who this might be right forHypophosphatasia Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan 13
Not applicableLooking for participantsNCT05234567What this trial is testingA Prospective Sub-Study of the Global Hypophosphatasia RegistryWho this might be right forHypophosphatasia Alexion Pharmaceuticals, Inc. 30
Not applicableStudy completedNCT04195763What this trial is testingPatient Reported Outcomes in Adults With Pediatric-onset Hypophosphatasia Treated With Strensiq® (Asfotase Alfa)Who this might be right forHypophosphatasia Alexion Pharmaceuticals, Inc. 50
Testing effectiveness (Phase 2)Study completedNCT01163149What this trial is testingSafety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)Who this might be right forHypophosphatasia Alexion Pharmaceuticals, Inc. 19
Early research (Phase 1)Study completedNCT00739505What this trial is testingSafety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)Who this might be right forHypophosphatasia (HPP) Alexion Pharmaceuticals, Inc. 6
Testing effectiveness (Phase 2)Study completedNCT01205152What this trial is testingExtension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP)Who this might be right forHypophosphatasia Alexion Pharmaceuticals, Inc. 10
Large-scale testing (Phase 3)Study completedNCT01176266What this trial is testingOpen-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP)Who this might be right forHypophosphatasia Alexion Pharmaceuticals, Inc. 69
Not applicableUnknownNCT06161142What this trial is testingCharacteristics of Hypophosphatasia in Adult Patients in RheumatologyWho this might be right forHypophosphatasia University of Bonn 60
Not applicableStudy completedNCT02291497What this trial is testingBurden of Disease in Hypophosphatasia (HPP)Who this might be right forHypophosphatasia Wuerzburg University Hospital 114