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Results for “Hypophosphatasia (HPP)”

34 trials

Showing 20 of 34 results

Post-approval studies (Phase 4)WithdrawnNCT06015750
What this trial is testing

Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Not applicableStudy completedNCT02235493
What this trial is testing

Non-interventional Substudy of ALX-HPP-502 to Assess Natural History of Patients With Juvenile-onset HPP Who Served as Historical Controls in ENB-006-09

Who this might be right for
HypophosphatasiaBone Disease
Alexion Pharmaceuticals, Inc. 6
Not applicableUnknownNCT04181164
What this trial is testing

Evaluation of Bone Architecture and Bone Strength in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Hvidovre University Hospital 30
Testing effectiveness (Phase 2)Study completedNCT01163149
What this trial is testing

Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 19
Large-scale testing (Phase 3)Active Not RecruitingNCT06079281
What this trial is testing

Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 124
Large-scale testing (Phase 3)Study completedNCT01176266
What this trial is testing

Open-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 69
Not applicableApproved For MarketingNCT02496689
What this trial is testing

Expanded Access Program for Asfotase Alfa Treatment for Patients With Infantile- or Juvenile-onset Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Not applicableUnknownNCT06161142
What this trial is testing

Characteristics of Hypophosphatasia in Adult Patients in Rheumatology

Who this might be right for
Hypophosphatasia
University of Bonn 60
Testing effectiveness (Phase 2)Study completedNCT02456038
What this trial is testing

Safety and Efficacy of Asfotase Alfa in Patients With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan 13
Not applicableStudy completedNCT04195763
What this trial is testing

Patient Reported Outcomes in Adults With Pediatric-onset Hypophosphatasia Treated With Strensiq® (Asfotase Alfa)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 50
Not applicableStudy completedNCT02104219
What this trial is testing

Retrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 32
Testing effectiveness (Phase 2)Study completedNCT01406977
What this trial is testing

Dose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Ultragenyx Pharmaceutical Inc 8
Not applicableStudy completedNCT02291497
What this trial is testing

Burden of Disease in Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Wuerzburg University Hospital 114
Not applicableLooking for participantsNCT07390240
What this trial is testing

The Effect of Monoallelic Variants in the ALPL Gene on the Natural Course of Hypophosphatasia in Russia

Who this might be right for
Hypophosphatasia
AstraZeneca 55
Large-scale testing (Phase 3)Active Not RecruitingNCT06079359
What this trial is testing

Phase 3 Study of ALXN1850 in Treatment-Naïve Pediatric Participants With HPP

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 30
Post-approval studies (Phase 4)Study completedNCT02531867
What this trial is testing

Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 13
Post-approval studies (Phase 4)WithdrawnNCT04189315
What this trial is testing

Relieving Burden of Hypophosphatasia in Adults With Functional Impairment Due to Chronic Disease

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Study completedNCT00952484
What this trial is testing

Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 13
Testing effectiveness (Phase 2)WithdrawnNCT00894075
What this trial is testing

Safety and Efficacy Study of ENB-0040 in Juvenile Patients With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Not applicableLooking for participantsNCT05234567
What this trial is testing

A Prospective Sub-Study of the Global Hypophosphatasia Registry

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 30
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