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Results for “Hypophosphatasia (HPP)”

33 trials

Showing 20 of 33 results

Post-approval studies (Phase 4)WithdrawnNCT04189315
What this trial is testing

Relieving Burden of Hypophosphatasia in Adults With Functional Impairment Due to Chronic Disease

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Not applicableStudy completedNCT02291497
What this trial is testing

Burden of Disease in Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Wuerzburg University Hospital 114
Post-approval studies (Phase 4)WithdrawnNCT06015750
What this trial is testing

Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Study completedNCT01406977
What this trial is testing

Dose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Ultragenyx Pharmaceutical Inc 8
Not applicableStudy completedNCT04195763
What this trial is testing

Patient Reported Outcomes in Adults With Pediatric-onset Hypophosphatasia Treated With Strensiq® (Asfotase Alfa)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 50
Testing effectiveness (Phase 2)Looking for participantsNCT07179640
What this trial is testing

Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALE1 in Healthy Adults and Adults With Hypophosphatasia in Order to Identify Suitable Doses of ALE1

Who this might be right for
Hypophosphatasia (HPP)
Alesta Therapeutics 120
Testing effectiveness (Phase 2)Study completedNCT01163149
What this trial is testing

Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 19
Testing effectiveness (Phase 2)Study completedNCT02797821
What this trial is testing

Pharmacokinetic and Dose Response Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 27
Early research (Phase 1)Study completedNCT00739505
What this trial is testing

Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 6
Testing effectiveness (Phase 2)Study completedNCT00744042
What this trial is testing

Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 11
Not applicableLooking for participantsNCT05234567
What this trial is testing

A Prospective Sub-Study of the Global Hypophosphatasia Registry

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 30
Large-scale testing (Phase 3)Active Not RecruitingNCT06079281
What this trial is testing

Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 124
Post-approval studies (Phase 4)Study completedNCT02531867
What this trial is testing

Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 13
Not applicableStudy completedNCT02104219
What this trial is testing

Retrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 32
Not applicableEnrolling By InvitationNCT02306720
What this trial is testing

Registry of Patients With Hypophosphatasia

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 1,571
Not applicableUnknownNCT06161142
What this trial is testing

Characteristics of Hypophosphatasia in Adult Patients in Rheumatology

Who this might be right for
Hypophosphatasia
University of Bonn 60
Not applicableStudy completedNCT01419028
What this trial is testing

A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 48
Not applicableUnknownNCT04181164
What this trial is testing

Evaluation of Bone Architecture and Bone Strength in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Hvidovre University Hospital 30
Testing effectiveness (Phase 2)Study completedNCT01203826
What this trial is testing

Extension Study of Protocol ENB-006-09 - Study of Asfotase Alfa in Children With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 12
Testing effectiveness (Phase 2)Study completedNCT01205152
What this trial is testing

Extension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 10
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