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Results for “ICANS”

13 trials

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Showing 13 of 13 results

Not applicableLooking for participantsNCT07075523
What this trial is testing

Neuroimaging and Biomarkers of Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy

Who this might be right for
CAR T-Cell Therapy
University of California, San Diego 36
Post-approval studies (Phase 4)Looking for participantsNCT06706102
What this trial is testing

Temporal Characterization of Extracellular Vesicles During Cellular Therapy Using CAR-T Cells and During the Occurrence of Immune Effector Cell-Associated Neurotoxicity Syndrome

Who this might be right for
Immune Effector Cell Associated Neurotoxicity Syndrome
Centre Hospitalier Universitaire de Saint Etienne 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT03016377
What this trial is testing

Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL

Who this might be right for
Acute Lymphoblastic LeukemiaImmune System DiseasesImmunoproliferative Disorders
UNC Lineberger Comprehensive Cancer Center 17
Early research (Phase 1)WithdrawnNCT05700630
What this trial is testing

Ph1 Study of FT538 Alone and With Vorinostat for Persistent Low-Level HIV Viremia

Who this might be right for
HIV-1-infectionARTCd4+ Lymphocyte Deficiency+2 more
Masonic Cancer Center, University of Minnesota
Testing effectiveness (Phase 2)Looking for participantsNCT06430736
What this trial is testing

PRONTO Trial (PRophylactic Versus ON-demand Use of TOcilizumab)

Who this might be right for
MyelomaLymphomaLeukemia
Insel Gruppe AG, University Hospital Bern 100
Early research (Phase 1)Looking for participantsNCT07169487
What this trial is testing

Adjunctive Methylene Blue for Immunotherapy-related CRS and ICANS: Phase I Study

Who this might be right for
Cytokine Release SyndromeICANS
Institute of Hematology & Blood Diseases Hospital, China 18
Early research (Phase 1)Not Yet RecruitingNCT07166549
What this trial is testing

Bispecific CAR T Cells for B-cell Malignancies (BaseCAR-01 Trial)

Who this might be right for
B Cell MalignanciesB-cell LeukemiaB Cell Lymphoma+2 more
University Hospital, Basel, Switzerland 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT04975555
What this trial is testing

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

Who this might be right for
Cytokine Release SyndromeICANSLymphoma, Non-Hodgkin+2 more
University of Alabama at Birmingham 30
Testing effectiveness (Phase 2)Looking for participantsNCT05972135
What this trial is testing

Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma

Who this might be right for
Multiple Myeloma
SCRI Development Innovations, LLC 100
Testing effectiveness (Phase 2)Looking for participantsNCT07106671
What this trial is testing

A Phase II Study of Siltuximab for CRS/ICANs After CAR-T in Multiple Myeloma

Who this might be right for
CRS - Cytokine Release SyndromeMyeloma
Institute of Hematology & Blood Diseases Hospital, China 20
Not applicableNot Yet RecruitingNCT07375628
What this trial is testing

Neurological and Cognitive Dysfunction Following CAR-T Treatment. ICANS and Beyond

Who this might be right for
CAR T Cell TherapyICANSCognitive and Executive Dysfunction
Karolinska University Hospital 10
Not applicableStudy completedNCT05811117
What this trial is testing

Multicenter Study Using IMC to Analyze the Impact of ICANS on Microglia

Who this might be right for
ICANS, Grade UnspecifiedCAR T-Cell-Related Encephalopathy Syndrome
University of Freiburg 8
Not applicableStudy completedNCT05040230
What this trial is testing

EEG Encephalopathy Patterns in Immune Effectors Cells-associated Neurotoxicity Syndrome (ICANS)Lay Language

Who this might be right for
Immune Effector Cell EncephalopathyNeurotoxicity
University Hospital, Montpellier 40