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Results for “IGF1R”

85 trials

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Showing 20 of 85 results

Testing effectiveness (Phase 2)Study completedNCT01016015
What this trial is testing

Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma

Who this might be right for
Metastatic OsteosarcomaRecurrent Adult Soft Tissue SarcomaRecurrent Osteosarcoma+2 more
National Cancer Institute (NCI) 178
Early research (Phase 1)Study completedNCT01008566
What this trial is testing

Cixutumumab and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer

Who this might be right for
Adult Hepatocellular CarcinomaAdvanced Adult Hepatocellular CarcinomaLocalized Non-Resectable Adult Liver Carcinoma+1 more
National Cancer Institute (NCI) 21
Early research (Phase 1)Study completedNCT02507583
What this trial is testing

Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma

Who this might be right for
Malignant GliomaNeoplasms
david andrews 33
Not applicableUnknownNCT02916394
What this trial is testing

In Vivo IGF-1R Molecular Imaging Using [68Ga]- Labelling Anti-IGF-1R Affibody Molecule

Who this might be right for
Molecular Imaging
Harbin Medical University 100
Large-scale testing (Phase 3)Study completedNCT06384547
What this trial is testing

A Randomized, Controlled, Safety and Tolerability Study of VRDN-001 in Participants With Thyroid Eye Disease (TED)

Who this might be right for
Thyroid Eye Disease
Viridian Therapeutics, Inc. 231
Large-scale testing (Phase 3)Active Not RecruitingNCT02306161
What this trial is testing

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Who this might be right for
Metastatic Ewing SarcomaMetastatic Malignant Neoplasm in the BoneMetastatic Malignant Neoplasm in the Bone Marrow+3 more
National Cancer Institute (NCI) 312
Early research (Phase 1)WithdrawnNCT01182883
What this trial is testing

A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Brain Stem NeoplasmsGliomaPinealoma
National Cancer Institute (NCI)
Not applicableUnknownNCT04710186
What this trial is testing

AR, IGF-IR, IR and Peripheral Artery Disease

Who this might be right for
Androgen Receptor AbnormalInsulin-Like Growth Factor I DeficiencyInsulin Receptor, Defect in
University of Catanzaro 30
Early research (Phase 1)Study completedNCT02103283
What this trial is testing

A Phase 1, Open-Label Study of Teprotumumab in Patients With Diabetic Macular Edema (DME)

Who this might be right for
Diabetic Macular Edema
Amgen 5
Testing effectiveness (Phase 2)Ended earlyNCT00791544
What this trial is testing

Dose Finding Study of AVE1642 in Patients With Advanced or Metastatic Liver Carcinoma

Who this might be right for
Liver Carcinoma
Sanofi 13
Early research (Phase 1)Study completedNCT01725555
What this trial is testing

Assess the Effect of Food on the Bioavailability of the IGF-1R Inhibitor AXL1717 in Patients With Advanced Malignant Tumors

Who this might be right for
Solid TumorsHematological Malignancies
Axelar AB 13
Early research (Phase 1)Study completedNCT00785538
What this trial is testing

IMC-A12 in Participants With Tumors Who No Longer Respond to Treatment or For Whom No Treatment is Available

Who this might be right for
Advanced Solid Tumors
Eli Lilly and Company 24
Testing effectiveness (Phase 2)Ended earlyNCT00807612
What this trial is testing

QUILT-2.017: Phase 1b/2 Study of AMG 479 in Combination With Paclitaxel and Carboplatin for 1st Line Treatment of Advanced Squamous Non-Small Cell Lung Cancer

Who this might be right for
Advanced Squamous Non-Small Cell Lung Cancer
NantCell, Inc. 15
Not applicableStudy completedNCT03498417
What this trial is testing

Anti-insulin-like Growth Factor-1 Receptor (IGF-1R) Antibodies in Graves' Disease and Graves' Orbitopathy

Who this might be right for
Graves OphthalmopathyGraves DiseaseAutoimmune Thyroiditis
University of Pisa 135
Very early researchActive Not RecruitingNCT06866548
What this trial is testing

Safety and Efficacy Evaluation of Anti IGF-1R Monoclonal Antibody Combined With Anti-PD-1 Monoclonal Antibody in Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer

Who this might be right for
mCRPC
Shanghai Changzheng Hospital 7
Not applicableStudy completedNCT04767750
What this trial is testing

Role of LncRNA H19 in The Regulation of IGF-1R Expression

Who this might be right for
Hepatocellular CarcinomaType 2 DiabetesCancer
Mansoura University 101
Testing effectiveness (Phase 2)Study completedNCT00799240
What this trial is testing

MK-0646 Insulin Growth Factor 1 Receptor Antibody in Stage IIIb or IV Metastatic Non-Squamous Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
University of Kansas 27
Testing effectiveness (Phase 2)Ended earlyNCT00778817
What this trial is testing

IMC-A12 With Mitotane vs Mitotane Alone in Recurrent, Metastatic, or Primary ACC That Cannot Be Removed by Surgery

Who this might be right for
Recurrent Adrenocortical CarcinomaStage III Adrenocortical CarcinomaStage IV Adrenocortical Carcinoma
National Cancer Institute (NCI) 20
Testing effectiveness (Phase 2)Ended earlyNCT03041701
What this trial is testing

Insulin-like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination With the Src Family Kinase (SFK) Inhibitor Dasatinib in People With Embryonal and Alveolar Rhabdomyosarcoma

Who this might be right for
RhabdomyosarcomaRhabdomyosarcoma, AlveolarRhabdomyosarcoma, Embryonal
National Cancer Institute (NCI) 14
Large-scale testing (Phase 3)Study completedNCT05176639
What this trial is testing

A Safety, Tolerability and Efficacy Study of Veligrotug (VRDN 001) in Healthy Volunteers and Participants With Thyroid Eye Disease (TED) ( THRIVE )

Who this might be right for
Thyroid Eye Disease
Viridian Therapeutics, Inc. 113
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