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Results for “IGF1R”

85 trials

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Showing 20 of 85 results

Early research (Phase 1)Study completedNCT00785941
What this trial is testing

IMC-A12 Every 2 Weeks in Patients With Tumors Who No Longer Respond to Treatment or No Treatment is Available

Who this might be right for
Advanced Solid Tumors
Eli Lilly and Company 16
Large-scale testing (Phase 3)Study completedNCT05176639
What this trial is testing

A Safety, Tolerability, and Efficacy Study of Veligrotug (VRDN 001) in Participants With Thyroid Eye Disease (TED)

Who this might be right for
Thyroid Eye Disease
Viridian Therapeutics, Inc. 113
Testing effectiveness (Phase 2)Ended earlyNCT01721577
What this trial is testing

Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant Astrocytomas

Who this might be right for
GlioblastomaGliosarcomaAnaplastic Astrocytoma+3 more
Rush University Medical Center 10
Not applicableStudy completedNCT01365962
What this trial is testing

Biomarker in Tumor Tissue Samples From Patients With Rhabdomyosarcoma

Who this might be right for
Sarcoma
Children's Oncology Group 60
Testing effectiveness (Phase 2)Study completedNCT00630552
What this trial is testing

QUILT-2.019: A Study of AMG 655 or AMG 479 in Combination With Gemcitabine for Treatment of Metastatic Pancreatic Cancer

Who this might be right for
Adenocarcinoma of the PancreasMetastatic Pancreatic CancerPancreatic Cancer
NantCell, Inc. 138
Large-scale testing (Phase 3)Study completedNCT06021054
What this trial is testing

An Efficacy, Safety, and Tolerability Study of Veligrotug (VRDN-001), in Participants With Chronic Thyroid Eye Disease (TED)

Who this might be right for
Thyroid Eye Disease
Viridian Therapeutics, Inc. 188
Early research (Phase 1)Study completedNCT01536145
What this trial is testing

CP-751,871 Treatment For Patients With Multiple Myeloma

Who this might be right for
Multiple Myeloma
Pfizer 47
Early research (Phase 1)Study completedNCT01062620
What this trial is testing

A Dose Escalating Clinical Trial of the IGF-1 Receptor Inhibitor AXL1717 in Patients With Advanced Cancer

Who this might be right for
Solid Tumors
Axelar AB 49
Testing effectiveness (Phase 2)Study completedNCT01561456
What this trial is testing

Study of AXL1717 Compared to Docetaxel to Treat Squamous Cell Carcinoma or Adenocarcinoma of the Lung

Who this might be right for
Non-small-cell Lung CancerSquamous Cell CarcinomaAdenocarcinoma of the Lung
Axelar AB 100
Testing effectiveness (Phase 2)Study completedNCT00684983
What this trial is testing

Capecitabine and Lapatinib Ditosylate With or Without Cixutumumab in Treating Patients With Previously Treated HER2-Positive Stage IIIB-IV Breast Cancer

Who this might be right for
HER2 Positive Breast CarcinomaRecurrent Breast CarcinomaStage IIIB Breast Cancer AJCC v7+2 more
National Cancer Institute (NCI) 64
Early research (Phase 1)WithdrawnNCT01182883
What this trial is testing

A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Brain Stem NeoplasmsGliomaPinealoma
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT02103283
What this trial is testing

A Phase 1, Open-Label Study of Teprotumumab in Patients With Diabetic Macular Edema (DME)

Who this might be right for
Diabetic Macular Edema
Amgen 5
Testing effectiveness (Phase 2)Study completedNCT00551213
What this trial is testing

Determine the Activity of Robatumumab (SCH 717454, MK-7454) in Participants With Relapsed or Recurrent Colorectal Cancer (P04721, MK-7454-003)

Who this might be right for
Colorectal Cancer
Merck Sharp & Dohme LLC 67
Not applicableUnknownNCT02711865
What this trial is testing

Predictive Biomarkers for IGF1R Targeted Therapy in Ovarian Cancer

Who this might be right for
Ovarian Cancer
Hillel Yaffe Medical Center 20
Early research (Phase 1)Ended earlyNCT02538627
What this trial is testing

Phase 1 Combination Study of MM-151 With MM-121, MM-141, or Trametinib

Who this might be right for
Colorectal CancerNon-small Cell Lung CancerSquamous Cell Carcinoma of the Head and Neck
Merrimack Pharmaceuticals 5
Testing effectiveness (Phase 2)Ended earlyNCT00845039
What this trial is testing

Irinotecan and Cetuximab With or Without IMC-A12 for Treatment of Participants With Colon or Rectum Cancer Who Got Worse After Their First Treatment With Oxaliplatin and Bevacizumab

Who this might be right for
Colon CancerRectal Cancer
Eli Lilly and Company 4
Testing effectiveness (Phase 2)Study completedNCT00889382
What this trial is testing

A Study Evaluating Intermittent and Continuous OSI-906 and Weekly Paclitaxel in Patients With Recurrent Epithelial Ovarian Cancer (and Other Solid Tumors)

Who this might be right for
Ovarian CancerSolid Tumors
Astellas Pharma Inc 152
Testing effectiveness (Phase 2)Ended earlyNCT00617890
What this trial is testing

Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720)

Who this might be right for
OsteosarcomaSarcoma, Ewing'sPeripheral Neuroectodermal Tumor
Merck Sharp & Dohme LLC 219
Testing effectiveness (Phase 2)Study completedNCT00778167
What this trial is testing

Erlotinib Hydrochloride With or Without Cixutumumab in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Who this might be right for
Recurrent Non-small Cell Lung CancerStage IIIA Non-small Cell Lung CancerStage IIIB Non-small Cell Lung Cancer+1 more
National Cancer Institute (NCI) 18
Not applicableStudy completedNCT00763607
What this trial is testing

Retrospective Study Evaluating IGF1R And p95HER2 as Prognostic Factors in Non Small Cell Lung Cancer (NSCLC)

Who this might be right for
Non Small Cell Lung Cancer
Armando Santoro, MD 454
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