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Results for “IL-4R”

17 trials

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Showing 17 of 17 results

Testing effectiveness (Phase 2)Looking for participantsNCT06300203
What this trial is testing

Study of CM310 in Patients With Uncontrolled Seasonal Allergic Rhinitis

Who this might be right for
Seasonal Allergic Rhinitis
Beijing Tongren Hospital 120
Early research (Phase 1)Ended earlyNCT05794672
What this trial is testing

Investigate the Safety, Tolerability and Pharmacokinetics of Elarekibep in Healthy Japanese Subjects

Who this might be right for
Healthy Subjects (Indication: Asthma)
AstraZeneca 30
Large-scale testing (Phase 3)Active Not RecruitingNCT06554847
What this trial is testing

Evaluation of 611 in Combination With Topical Corticosteroid in Participants With Moderate to Severe Atopic Dermatitis

Who this might be right for
Dermatitis, AtopicEczema, Atopic
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. 400
Post-approval studies (Phase 4)Study completedNCT05036733
What this trial is testing

Effects of Interleukin (IL)- 4R-alpha Inhibition on Respiratory Microbiome and Immunologic Correlates in Severe Asthma

Who this might be right for
Asthma
University of Michigan 15
Testing effectiveness (Phase 2)Study completedNCT03749135
What this trial is testing

Dupilumab in Chronic Spontaneous Urticaria

Who this might be right for
Chronic Spontaneous UrticariaRecurrent Angioedema
Charite University, Berlin, Germany 72
Testing effectiveness (Phase 2)Active Not RecruitingNCT05575037
What this trial is testing

Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease

Who this might be right for
Nasal PolypsAsthma, Aspirin-InducedAspirin-Exacerbated Respiratory Disease+1 more
Brigham and Women's Hospital 17
Not applicableNot Yet RecruitingNCT07550452
What this trial is testing

Efficacy and Safety of Switching to Ivarmacitinib in Patients With Moderate-to-Severe Atopic Dermatitis With Inadequate Response to Interleukin-4 Receptor Alpha(IL-4Rα) Inhibitors: A Prospective, Multicenter, Real-World Study

Who this might be right for
Atopic Dermatitis (AD)
Peking University People's Hospital 300
Testing effectiveness (Phase 2)Study completedNCT02858895
What this trial is testing

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Who this might be right for
GlioblastomaGrade IV AstrocytomaGlioblastoma Multiforme+1 more
Medicenna Therapeutics, Inc. 47
Not applicableUnknownNCT05428410
What this trial is testing

Study on Biomarkers to Predict the Efficacy of IL-4R Monoclonal Antibody for Chronic Rhino-sinusitis With Polyps

Who this might be right for
Chronic Rhino-sinusitisIL-4RMonoclonal Antibody+1 more
Beijing Tongren Hospital 56
Large-scale testing (Phase 3)Study completedNCT06173284
What this trial is testing

Evaluation of 611(Recombinant Humanized Anti-interleukin-4 Receptor Alpha IgG4 Monoclonal Antibody) in Chinese Adults With Moderate to Severe Atopic Dermatitis

Who this might be right for
Dermatitis, Atopic
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. 519
Testing effectiveness (Phase 2)Study completedNCT03749148
What this trial is testing

Cholinergic Urticaria - Efficacy of Dupilumab

Who this might be right for
Cholinergic Urticaria
Charite University, Berlin, Germany 48
Large-scale testing (Phase 3)Looking for participantsNCT07042126
What this trial is testing

Evaluation of 611 in Chinese Adolescents With Moderate to Severe Atopic Dermatitis

Who this might be right for
Dermatitis, Atopic
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. 180
Not applicableLooking for participantsNCT04455906
What this trial is testing

Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism

Who this might be right for
Atopic Dermatitis
Boston Children's Hospital 111
Testing effectiveness (Phase 2)Study completedNCT00436670
What this trial is testing

Phase II Study to Evaluate the Efficacy of AMG 317

Who this might be right for
Asthma
Amgen 294
Not applicableNot Yet RecruitingNCT06743581
What this trial is testing

Phase I/II Study of Neoadjuvant Cemiplimab and Dupilumab in Early-Stage Non-Small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung CancerImmunotherapyNeoadjuvant Therapy
Centre hospitalier de l'Université de Montréal (CHUM) 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT06324812
What this trial is testing

Evaluation of 611 in Chinese Children and Adolescents With Moderate to Severe Atopic Dermatitis

Who this might be right for
Dermatitis, Atopic
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. 124
Testing effectiveness (Phase 2)Looking for participantsNCT06088771
What this trial is testing

Neoadjuvant Dupilumab and Cemiplimab in Patients With Early-stage Resectable NSCLC

Who this might be right for
Non-Small Cell Lung Cancer
Icahn School of Medicine at Mount Sinai 21