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Results for “IL-6 Inhibitor”

22 trials

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Showing 20 of 22 results

Not applicableStudy completedNCT07786350
What this trial is testing

Thiamine, Ascorbic Acid, and Their Combination on MMP-9/TIMP-1 and Inflammatory Balance in Sepsis

Who this might be right for
Sepsis and Septic Shock
Universitas Sumatera Utara 40
Early research (Phase 1)Study completedNCT00955812
What this trial is testing

STAT3 Inhibitor for Solid Tumors

Who this might be right for
Advanced CancerSolid Tumor
M.D. Anderson Cancer Center 24
Testing effectiveness (Phase 2)Looking for participantsNCT05428007
What this trial is testing

Interleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV Melanoma

Who this might be right for
MelanomaUnresectable Melanoma
NYU Langone Health 105
Testing effectiveness (Phase 2)Study completedNCT02293837
What this trial is testing

Tocilizumab (TCZ) in New-onset Type 1 Diabetes

Who this might be right for
Type 1 Diabetes MellitusNew-onset Type 1 Diabetes MellitusT1DM+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 136
Testing effectiveness (Phase 2)Study completedNCT04343989
What this trial is testing

Placebo-controlled Safety and Dose-finding Study for the Use of the IL-6 Inhibitor Clazakizumab in Patients With Life-threatening COVID-19 Infection

Who this might be right for
COVID-19
NYU Langone Health 178
Early research (Phase 1)UnknownNCT00353756
What this trial is testing

Phase 1 Study of Safety and Biological Effects of C326, an Inhibitor of IL-6, in Crohn's Disease

Who this might be right for
Crohn's Disease
Avidia 52
Testing effectiveness (Phase 2)Study completedNCT04333914
What this trial is testing

Prospective Study in Patients With Advanced or Metastatic Cancer and SARS-CoV-2 Infection

Who this might be right for
SARS-CoV-2 (COVID-19) InfectionAdvanced or Metastatic Hematological or Solid Tumor
Centre Leon Berard 19
Testing effectiveness (Phase 2)Ended earlyNCT04381052
What this trial is testing

Study for the Use of the IL-6 Inhibitor Clazakizumab in Patients With Life-threatening COVID-19 Infection

Who this might be right for
COVID-19
Columbia University 1
Early research (Phase 1)UnknownNCT04560205
What this trial is testing

Tocilizumab in COVID-19 Lahore General Hospital

Who this might be right for
SARS-CoV Infection
Lahore General Hospital 50
Not applicableUnknownNCT06390709
What this trial is testing

PREDICT Therapy Selection for JAK, T-cell, or IL-6 Inhibitor Therapies Using a Molecular Signature Response Classifier (PREDICT)

Who this might be right for
Rheumatoid Arthritis
Scipher Medicine 1,100
Testing effectiveness (Phase 2)Active Not RecruitingNCT03999749
What this trial is testing

A Phase II Study of the Interleukin-6 Receptor Inhibitor Tocilizumab in Combination With Ipilimumab and Nivolumab in Patients With Unresectable Stage III or Stage IV Melanoma

Who this might be right for
Melanoma
NYU Langone Health 71
Not applicableStudy completedNCT03601611
What this trial is testing

Checkpoint Inhibitor Induced Colitis and Arthritis -Immunomodulation With IL-6 Blockade and Exploration of Disease Mechanisms

Who this might be right for
Solid TumorColitisArthritis
Herlev Hospital 20
Post-approval studies (Phase 4)UnknownNCT01835613
What this trial is testing

Evaluation Effects of Treatment With IL-6R Inhibitor on Clinical Response and Biomarkers in Patients With Rheumatoid Arthritis (RA) Not Responding to DMARDs and/or a First Biological Agent.

Who this might be right for
Rheumatoid Arthritis (RA)
Osservatorio Epidemiologico GISEA 150
Large-scale testing (Phase 3)Active Not RecruitingNCT07263776
What this trial is testing

Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Anterior Circulation Large Vessel Occlusion Stroke -2

Who this might be right for
Acute Ischemic Stroke
Capital Medical University 692
Large-scale testing (Phase 3)UnknownNCT05090410
What this trial is testing

Efficacy and Safety of Selective JAK 1 Inhibitor Filgotinib in Active Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate

Who this might be right for
Rheumatoid ArthritisJAK InhibitorIL-6 Inhibitor+2 more
Atsushi Kawakami 400
Early research (Phase 1)WithdrawnNCT02842541
What this trial is testing

Safety Study of Intravitreal EBI-031 Given as a Single or Repeat Injection to Subjects With Diabetic Macular Edema

Who this might be right for
Diabetic Macular Edema
Eleven Biotherapeutics
Early research (Phase 1)Not Yet RecruitingNCT07484113
What this trial is testing

IL6-receptor Inhibitor Iwith Belumosudil for the Treatment of Belumosudil-refractory cGVHD

Who this might be right for
cGVHD
Stanford University 10
Large-scale testing (Phase 3)Study completedNCT02477059
What this trial is testing

Effect of the Interleukin-6 Receptor Antagonist Tocilizumab in Patients With Hand Osteoarthritis

Who this might be right for
Hand Osteoarthritis
Assistance Publique - Hôpitaux de Paris 104
Large-scale testing (Phase 3)Study completedNCT04724629
What this trial is testing

Survival TRial Using CytoKines in COVID-19 (STRUCK Trial)

Who this might be right for
Covid19
University of Sao Paulo 60
Large-scale testing (Phase 3)Looking for participantsNCT07509645
What this trial is testing

Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Posterior Circulation Large Vessel Occlusion Stroke

Who this might be right for
Ischemic Stroke
Capital Medical University 348
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