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Results for “Imatinib Intolerant”

53 trials

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Showing 20 of 53 results

Testing effectiveness (Phase 2)Study completedNCT00101816
What this trial is testing

Dasatinib (BMS-354825) in Subjects With Myeloid Blast Phase Chronic Myeloid Leukemia Resistant to or Intolerant of Imatinib Mesylate

Who this might be right for
Chronic Myeloid LeukemiaBlast Crisis
Bristol-Myers Squibb 124
Large-scale testing (Phase 3)WithdrawnNCT00349518
What this trial is testing

Study of Dasatinib in Imatinib Resistant or Intolerant Subjects With Chronic or Advanced Phase CML or Philadelphia Chromosome Positive ALL

Who this might be right for
Chronic Myeloid LeukemiaAcute Lymphoblastic Leukemia
Bristol-Myers Squibb
Not applicableNo Longer AvailableNCT00413270
What this trial is testing

Oral Nilotinib in Adults With Chronic Myeloid Leukemia (CML) in Blast Crisis Who Are Imatinib Resistant or Intolerant

Who this might be right for
Chronic Myelogenous Leukemia
Novartis Pharmaceuticals
Not applicableStudy completedNCT00538109
What this trial is testing

An Open-Label, Multicenter, Expanded Access Study of Oral AMN 107 in Adult Patients With Imatinib (Glivec®/Gleevec®_ - Resistant or Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase

Who this might be right for
Leukemia, Myeloid, Chronic
King Faisal Specialist Hospital & Research Center 8
Testing effectiveness (Phase 2)Looking for participantsNCT01746836
What this trial is testing

Ponatinib Hydrochloride as Second Line Therapy in Treating Patients With Chronic Myeloid Leukemia in Chronic Phase Resistant or Intolerant to Imatinib Mesylate, Dasatinib, or Nilotinib

Who this might be right for
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositivePhiladelphia Chromosome Positive, BCR-ABL1 Positive Chronic Myelogenous LeukemiaRecurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Study completedNCT00482703
What this trial is testing

Dasatinib in Chronic Phase Philadelphia Chromosome Positive Chronic Myeloid Leukemia

Who this might be right for
Myeloid Leukemia, Chronic
Bristol-Myers Squibb 23
Testing effectiveness (Phase 2)Ended earlyNCT01391611
What this trial is testing

Pazopanib in Imatinib Refractory or Intolerant Gastrointestinal Stromal Tumors (GIST)

Who this might be right for
Gastrointestinal Stromal Tumor (GIST)
Kristen Ganjoo 25
Testing effectiveness (Phase 2)Study completedNCT01068769
What this trial is testing

Regorafenib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor

Who this might be right for
Gastrointestinal Stromal Tumor
Suzanne George, MD 34
Testing effectiveness (Phase 2)Study completedNCT00529763
What this trial is testing

Dasatinib in Imatinib Resistant/Intolerant Chinese CML (Chronic and Advanced Phase) Subjects

Who this might be right for
Leukemia
Bristol-Myers Squibb 121
Not applicableNo Longer AvailableNCT04518644
What this trial is testing

Nilotinib, for Patients With CML-CP or CML-AP

Who this might be right for
Chronic Myelogenous Leukemia (CML)
Novartis Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT00511303
What this trial is testing

Protein-Tyrosine Kinase Inhibitor (STI571) for Treatment of Patients With Ph+ Chronic Myeloid Leukemia

Who this might be right for
Chronic Myeloid Leukemia
University of Bologna 200
Testing effectiveness (Phase 2)Study completedNCT00570635
What this trial is testing

XL820 in Adults With Advanced GIST Resistant to Imatinib and/or Sunitinib

Who this might be right for
Gastrointestinal Stromal TumorsGastrointestinal Neoplasms
Exelixis 16
Early research (Phase 1)Ended earlyNCT01426334
What this trial is testing

Dasatinib and Cyclosporine in Treating Patients With Chronic Myelogenous Leukemia Refractory or Intolerant to Imatinib Mesylate

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaChronic Myelogenous Leukemia, BCR-ABL1 PositiveChronic Phase Chronic Myelogenous Leukemia+1 more
National Cancer Institute (NCI) 4
Testing effectiveness (Phase 2)Study completedNCT00171223
What this trial is testing

An Extension Study to Determine the Efficacy and Safety of STI571 in Participants With Chronic Myeloid Leukemia Who Are Refractory to or Intolerant of Interferon-Alpha

Who this might be right for
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Novartis Pharmaceuticals 532
Not applicableStudy completedNCT01475110
What this trial is testing

Observational Study in Adults With Imatinib-resistant/Intolerant Chronic Myeloid Leukemia Treated With Nilotinib

Who this might be right for
Chronic Myeloid Leukaemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 19
Testing effectiveness (Phase 2)Study completedNCT00618319
What this trial is testing

An Open-Label, 18FDG-PET Pharmacodynamic Assessment of the Effect of BIIB021 in Subjects With Gastrointestinal Stromal Tumors (GIST)

Who this might be right for
GIST
Biogen 20
Large-scale testing (Phase 3)Study completedNCT00123474
What this trial is testing

Chronic Myelogenous Leukemia (CML) - Follow on: Study of BMS-354825 in Subjects With CML

Who this might be right for
Myeloid Leukemia, Chronic, Chronic-Phase
Bristol-Myers Squibb 724
Post-approval studies (Phase 4)Study completedNCT01368523
What this trial is testing

Study of Oral AMN107 (Nilotinib) in Adult Patients With Imatinib - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase Previously Enrolled to CAMN107A2109 Trial

Who this might be right for
Chronic Myelogenous Leukemia
Novartis Pharmaceuticals 19
Not applicableEnded earlyNCT01073644
What this trial is testing

Post Marketing Surveillance On The Safety And Tolerability Of Sunitinib Malate (Sutent) For Filipino Patients

Who this might be right for
Metastatic Renal Cell Carcinoma
Pfizer 3
Testing effectiveness (Phase 2)Study completedNCT01844765
What this trial is testing

Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients.

Who this might be right for
Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia
Novartis Pharmaceuticals 59
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