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Results for “Immune Dysregulation Syndromes”

39 trials

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Showing 20 of 39 results

Not applicableEnrolling By InvitationNCT06966687
What this trial is testing

Protective Effect of Ulinastatin and Thymosin α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA XI)

Who this might be right for
Aortic DissectionAortic Dissection Aneurysm
Nanjing Medical University 200
Testing effectiveness (Phase 2)Study completedNCT06897358
What this trial is testing

Leniolisib for Immune Dysregulation in CVID

Who this might be right for
Common Variable Immunodeficiency (CVID)
Pharming Technologies B.V. 27
Not applicableLooking for participantsNCT06339177
What this trial is testing

Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study

Who this might be right for
Lymphohistiocytosis, HemophagocyticSecondary Hemophagocytic LymphohistiocytosisMacrophage Activation Syndrome+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 300
Testing effectiveness (Phase 2)Study completedNCT02277639
What this trial is testing

Reduced Intensity Conditioning Using CD3+/CD19+ Depletion for Non Malignant Transplantable Diseases

Who this might be right for
Bone Marrow Failure SyndromesImmunodeficienciesImmune Dysregulation Syndromes
Children's Hospital of Philadelphia 2
Not applicableStudy completedNCT03576742
What this trial is testing

Severe Immune Cytopenia Registry Www.Sic-reg.Org

Who this might be right for
Immune ThrombocytopeniaAutoimmune Hemolytic AnemiaEvans Syndrome+1 more
Medical University of Graz 80
Not applicableStudy completedNCT05339529
What this trial is testing

Protective Effect of Thymosin α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA II)

Who this might be right for
Acute Aortic SyndromeAortic Dissection Type A
Nanjing Medical University 600
Early research (Phase 1)Looking for participantsNCT05241444
What this trial is testing

CD4^LVFOXP3 in Participants With IPEX

Who this might be right for
IPEX
Bacchetta, Rosa, MD 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07660783
What this trial is testing

Naive T Cell Deplete Grafts for GVHD Prevention in Non-Malignant Diseases

Who this might be right for
Bone Marrow FailureHemoglobinopathiesPrimary Immune Deficiency (PID)+4 more
Fred Hutchinson Cancer Center 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT02990819
What this trial is testing

Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies

Who this might be right for
ImmunodeficienciesImmune Dysregulation Syndromes
Children's Hospital of Philadelphia 60
Testing effectiveness (Phase 2)Study completedNCT05965726
What this trial is testing

RECOVER-VITAL: Platform Protocol, Appendix to Measure the Effects of Paxlovid on Long COVID Symptoms

Who this might be right for
Long COVID-19Long COVID
Kanecia Obie Zimmerman 964
Not applicableLooking for participantsNCT05584488
What this trial is testing

Allergy and Immunology Natural History Study

Who this might be right for
Immune DeficiencyImmune Dysregulation DisorderAllergic Inflammation
Columbia University 10,000
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Not applicableLooking for participantsNCT03215836
What this trial is testing

Obesity, Metabolic Dysregulation and the Airway Epithelium in Asthmatics

Who this might be right for
AsthmaObesityMetabolic Syndrome
University of Colorado, Denver 50
Not applicableLooking for participantsNCT07416201
What this trial is testing

Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy

Who this might be right for
Down Syndrome
National Institute of Allergy and Infectious Diseases (NIAID) 700
Very early researchLooking for participantsNCT02356653
What this trial is testing

Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC

Who this might be right for
LeukemiaInborn Errors of MetabolismBone Marrow Failure Syndromes+2 more
Children's Hospital of Philadelphia 100
Not applicableLooking for participantsNCT03851484
What this trial is testing

Sensory Symptoms in Tourette Syndrome

Who this might be right for
Tourette Syndrome
Vanderbilt University Medical Center 214
Not applicableLooking for participantsNCT06915831
What this trial is testing

Type 1 Diabetes and Obstructive Sleep Apnea

Who this might be right for
Sleep Apnea, ObstructiveType 1 Diabetes (T1D)
University of Chicago 40
Not applicableUnknownNCT04374721
What this trial is testing

Clinical Study on Circadian Genes Dysregulation in Patients With Glucocorticoid Disorders

Who this might be right for
Cushing SyndromeAdrenal InsufficiencyCushing Disease+1 more
University of Roma La Sapienza 44
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07697118
What this trial is testing

Study Evaluating a Gene Therapy for IPEX Syndrome Through the Expression of FOXP3 on Deficient T Cells to Produce Tregs-like.

Who this might be right for
The Immune Dysregulation Polyendocrinopathy Enteropathy X-linked Syndrome is a Primary Immunodeficiency Caused by Pathogenic Variants in Forkhead Box Protein 3
Assistance Publique - Hôpitaux de Paris 5
Not applicableNot Yet RecruitingNCT07735741
What this trial is testing

Immune Dysregulation During Sepsis: A Natural History Cohort

Who this might be right for
SepsisSeptic ShockSepsis-Associated Immune Dysregulation
National Heart, Lung, and Blood Institute (NHLBI) 500
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