Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Impaired Liver Function”

422 trials

Showing 20 of 422 results

Early research (Phase 1)Study completedNCT02070549
What this trial is testing

Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the LiverMetastatic Malignant Solid Neoplasm+1 more
National Cancer Institute (NCI) 46
Early research (Phase 1)Study completedNCT05916560
What this trial is testing

LY3437943 in Participants With Impaired and Normal Liver Function

Who this might be right for
HealthyHepatic Insufficiency
Eli Lilly and Company 43
Early research (Phase 1)Study completedNCT00651027
What this trial is testing

Study To Assess The Impact Of Hepatic Impairment On The Safety, Tolerability And Pharmacokinetics Of Single-Dose 200 Mg Of PF-868554

Who this might be right for
HEPATITIS C (HCV)
Pfizer 24
Not applicableStudy completedNCT03371537
What this trial is testing

Study of Hemodynamic Conditions Measured During Hepatectomy

Who this might be right for
Liver DysfunctionCirculatory; Change
University Hospital, Tours 9
Early research (Phase 1)Study completedNCT01185873
What this trial is testing

Danoprevir in Healthy Volunteers And Patients With Hepatic Impairment

Who this might be right for
Healthy Volunteer
Hoffmann-La Roche 81
Not applicableStudy completedNCT04004481
What this trial is testing

Metabolites of Tramadol in the Postoperative Surgical Patients

Who this might be right for
Abdominal SurgeryRespiratory FailureRenal Failure+2 more
Osijek University Hospital 50
Early research (Phase 1)Study completedNCT06093230
What this trial is testing

A Study in Subjects With Liver Function Injury and Subjects With Normal Liver Function

Who this might be right for
Subjects With Liver Function InjuryNormal Liver Function Subject
Shanghai Vinnerna Biosciences Co., Ltd. 24
Not applicableLooking for participantsNCT06857331
What this trial is testing

Perioperative Analgesia With Erector Spinae Plane Block in Liver Transplant Recipients

Who this might be right for
Liver TransplantErector Spina Plan Block
Bogomolets National Medical University 50
Early research (Phase 1)Study completedNCT05098054
What this trial is testing

Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Takeda 36
Early research (Phase 1)Study completedNCT00432627
What this trial is testing

Impact of Hepatic Impairment on the Pharmacokinetics of Deferasirox.

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals 24
Early research (Phase 1)Study completedNCT04694365
What this trial is testing

Safety and Pharmacokinetics of Fluzoparib in Healthy Subjects and Those With Impaired Liver Function

Who this might be right for
Hepatic ImpairmentHealthy Subjects
Jiangsu HengRui Medicine Co., Ltd. 24
Early research (Phase 1)Study completedNCT06340347
What this trial is testing

Learn How the Body Processes the Study Medicine Called Osivelotor (PF-07940367) in People With Loss of Liver Function

Who this might be right for
Liver Diseases
Pfizer 8
Not applicableLooking for participantsNCT07343037
What this trial is testing

Diagnosis of Lymphohistiocytic Hemophagocytosis in Intensive Care

Who this might be right for
Hepatic InsufficiencyCirrhosis, Liver
University Hospital, Strasbourg, France 100
Early research (Phase 1)Study completedNCT01919125
What this trial is testing

Pharmacokinetics of IDX719 in Participants With Normal and Impaired Hepatic Function (MK-1894-008)

Who this might be right for
Hepatitis C, Chronic
Merck Sharp & Dohme LLC 36
Early research (Phase 1)Study completedNCT04993404
What this trial is testing

Pharmacokinetics Of Jaktinib In Subjects With Hepatic Impairment And Normal Hepatic Function

Who this might be right for
Hepatic InsufficiencyHealthy Subjects
Suzhou Zelgen Biopharmaceuticals Co.,Ltd 24
Early research (Phase 1)Study completedNCT01670734
What this trial is testing

Pharmacokinetic and Tolerability of Alirocumab SAR236553 (REGN727) in Patients With Hepatic Impairment and in Healthy Subjects

Who this might be right for
Hypercholesterolemia
Sanofi 25
Early research (Phase 1)Study completedNCT06048302
What this trial is testing

PK and Safety in Participants Taking Obicetrapib With Moderate Hepatic Impairment Relative to Normal Hepatic Function

Who this might be right for
Hepatic ImpairmentHealthy
NewAmsterdam Pharma 18
Not applicableUnknownNCT05571332
What this trial is testing

Efficacy and Safety of Avatrombopag Combined With IST for the Treatment of HAAA and SAA With Abnormal Liver Function

Who this might be right for
Aplastic Anemia
Institute of Hematology & Blood Diseases Hospital, China 39
Early research (Phase 1)Study completedNCT04154774
What this trial is testing

Apalutamide in Participants With Severe Hepatic Impairment Compared With Participants With Normal Hepatic Function

Who this might be right for
Hepatic Impairment
Janssen Research & Development, LLC 18
Early research (Phase 1)Study completedNCT05624710
What this trial is testing

Evaluate the Pharmacokinetics and Safety of INCB054707 in Participants With Normal Hepatic Function and Participants With Hepatic Impairment

Who this might be right for
Renal InsufficiencyKidney Diseases
Incyte Corporation 25
Load More Results

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation