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Results for “Inherited Neuropathies”

663 trials

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Showing 20 of 663 results

Early research (Phase 1)Ended earlyNCT00996892
What this trial is testing

Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Genentech, Inc. 178
Not applicableUnknownNCT05750693
What this trial is testing

PIK3CA in HER2+ BC and pCR Trial

Who this might be right for
HER2-positive Breast Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 58
Testing effectiveness (Phase 2)Study completedNCT02595983
What this trial is testing

The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant

Who this might be right for
Transthyretin (TTR)-Mediated AmyloidosisFamilial Amyloidotic Polyneuropathy (FAP)ATTR Amyloidosis+1 more
Alnylam Pharmaceuticals 12
Not applicableLooking for participantsNCT07154394
What this trial is testing

Cardiac Amyloid Deposits and Heart Dysfunction in Alzheimer's Disease

Who this might be right for
Dementia, Alzheimer TypeMild Cognitive ImpairmentCardiac Amyloidosis
University Hospital, Essen 15
Not applicableLooking for participantsNCT03475173
What this trial is testing

New Non-invasive Modalities for Assessing Retinal Structure and Function

Who this might be right for
Ischemic Optic NeuropathyBranch Retinal Artery OcclusionHemianopia+2 more
Randy Kardon 500
Large-scale testing (Phase 3)Study completedNCT04298372
What this trial is testing

Frontline Lenalidomide for AL Amyloidosis Involving Myocardium

Who this might be right for
Amyloidosis Cardiac
Seoul National University Hospital 2
Large-scale testing (Phase 3)Looking for participantsNCT06672237
What this trial is testing

NTLA-2001 in ATTRv-PN

Who this might be right for
Neuromuscular DiseaseNeuromuscular Diseases (NMD)Neurodegenerative Disease+17 more
Intellia Therapeutics 60
Not applicableStudy completedNCT03616496
What this trial is testing

Assessment of 18F-Florbetaben Whole-body PET for the Detection of Cardiac and Extracardiac Sites of Amyloid Deposits

Who this might be right for
Cardiac Amyloidosis
Central Hospital, Nancy, France 67
Not applicableLooking for participantsNCT06866912
What this trial is testing

Observational Epidemiological Study of Patients Suffering From Systemic Amyloidosis

Who this might be right for
Cardiomyopathy
IRCCS Azienda Ospedaliero-Universitaria di Bologna 750
Not applicableStudy completedNCT03190577
What this trial is testing

Assessment of the Prevalence of TTR Amyloid Neuropathy in a Population of Patients With Neuropathy of Unknown Aetiology

Who this might be right for
Familial Amyloid NeuropathyTransthyretin Amyloidosis
Nantes University Hospital 400
Early research (Phase 1)Study completedNCT00078481
What this trial is testing

Phase 1 Trial of Idebenone to Treat Patients With Friedreich's Ataxia

Who this might be right for
Friedreich Ataxia
National Institute of Neurological Disorders and Stroke (NINDS) 16
Not applicableActive Not RecruitingNCT02327845
What this trial is testing

Phenotype, Genotype & Biomarkers in ALS and Related Disorders

Who this might be right for
Amyotrophic Lateral SclerosisFrontotemporal DementiaPrimary Lateral Sclerosis+3 more
University of Miami 708
Large-scale testing (Phase 3)Study completedNCT02791230
What this trial is testing

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 1,733
Not applicableLooking for participantsNCT07382128
What this trial is testing

Myocardial Perfusion CMR for Differentiating and Characterizing Hypertrophic Cardiomyopathy Phenotypes

Who this might be right for
HCM - Hypertrophic CardiomyopathyAnderson Fabry DiseaseCardiac Magnetic Resonance Imaging+1 more
IRCCS Azienda Ospedaliero-Universitaria di Bologna 250
Not applicableActive Not RecruitingNCT02596191
What this trial is testing

Tools for Therapeutic Evaluation in Charcot-Marie-Tooth Disease Type 1A: Outcome Measures and Biomarkers

Who this might be right for
Charcot-Marie-Tooth Disease Type 1A
Assistance Publique Hopitaux De Marseille 80
Large-scale testing (Phase 3)Study completedNCT03860935
What this trial is testing

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+2 more
Eidos Therapeutics, a BridgeBio company 632
Not applicableStudy completedNCT01203085
What this trial is testing

Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT

Who this might be right for
Charcot Marie Tooth Disease
University of Iowa 500
Not applicableUnknownNCT04061213
What this trial is testing

ATTR Amyloidosis in Elderly Patients With Aortic Stenosis

Who this might be right for
Aortic Stenosis SymptomaticAmyloidosis Cardiac
Insel Gruppe AG, University Hospital Bern 489
Testing effectiveness (Phase 2)Study completedNCT05054725
What this trial is testing

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

Who this might be right for
Non-Small Cell Lung Cancer
Revolution Medicines, Inc. 47
Large-scale testing (Phase 3)UnknownNCT01316744
What this trial is testing

Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain

Who this might be right for
Cancer
University of Glasgow 214
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