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Results for “Interleukin 12”

181 trials

Showing 20 of 181 results

Early research (Phase 1)Study completedNCT05781542
What this trial is testing

Clinical Trial to Evaluate the Safety and Immunogenicity of Synthetic DNAs Encoding NP-GT8 and IL-12, With or Without a TLR-agonist-Adjuvanted HIV Env Trimer 4571 Boost, in Adults Without HIV

Who this might be right for
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 46
Testing effectiveness (Phase 2)WithdrawnNCT04655807
What this trial is testing

JNJ-64304500 as Add-on Therapy in Participants With Active Crohn's Disease

Who this might be right for
Crohn Disease
Janssen Research & Development, LLC
Early research (Phase 1)Study completedNCT00007163
What this trial is testing

Monoclonal Antibody Treatment of Crohn's Disease

Who this might be right for
Crohn's Disease
National Institute of Allergy and Infectious Diseases (NIAID) 40
Not applicableStudy completedNCT06844565
What this trial is testing

Role of IL 12 and IL 23 as Potential Biomarkers in Diagnosis of Early Crohn's Disease

Who this might be right for
Interleukin 12Interleukin 23Biomarker+2 more
Tanta University 110
Testing effectiveness (Phase 2)Ended earlyNCT04095689
What this trial is testing

Docetaxel Chemotherapy and Pembrolizumab Plus Interleukin-12 Gene Therapy in Triple Negative Breast Cancer

Who this might be right for
Triple Negative Breast CancerAnthracycline-refractory TNBC
The Methodist Hospital Research Institute 8
Not applicableUnknownNCT04462120
What this trial is testing

IL-12RB and TNF-alpha Gene Polymorphism and Susceptibility and Progress of Covid-19 SARS-CoV-2: A Case Control Study

Who this might be right for
Covid-19
Assiut University 100
Testing effectiveness (Phase 2)Study completedNCT04470050
What this trial is testing

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal

Who this might be right for
Opioid Withdrawal
BioXcel Therapeutics Inc 225
Testing effectiveness (Phase 2)Study completedNCT00003017
What this trial is testing

Interleukin-12 in Treating Patients With Advanced or Recurrent Cancer of the Cervix

Who this might be right for
Cervical Cancer
Eastern Cooperative Oncology Group
Early research (Phase 1)Study completedNCT02555397
What this trial is testing

Phase 1 Trial of Interleukin 12 Gene Therapy for Locally Recurrent Prostate Cancer

Who this might be right for
Prostate Cancer
Henry Ford Health System 15
Early research (Phase 1)Study completedNCT02480374
What this trial is testing

Study of Safety & Biological Activity of IP IMNN-001 (also Known As GEN-1) with Neoadjuvant Chemo in Ovarian Cancer

Who this might be right for
Epithelial Ovarian CancerFallopian Tube CancerPrimary Peritoneal Cancer
Imunon 18
Testing effectiveness (Phase 2)Ended earlyNCT01300858
What this trial is testing

The Safety and Biological Activity of Intraperitoneal (IP) EGEN-001 Administered Alone and in Combination With Standard Chemotherapy in Colorectal Peritoneal Carcinomatosis Patients

Who this might be right for
Colorectal Cancer
EGEN, Inc. 4
Early research (Phase 1)Active Not RecruitingNCT03030378
What this trial is testing

Pembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors

Who this might be right for
Metastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Study completedNCT02343133
What this trial is testing

Safety Study of HemaMax™ (rHuIL-12) to Treat Acute Radiation Syndrome

Who this might be right for
Hematopoietic Syndrome Due to Acute Radiation Syndrome
Neumedicines Inc. 200
Early research (Phase 1)Study completedNCT02431767
What this trial is testing

Evaluating the Safety and Immunogenicity of PENNVAX®-GP DNA Vaccine and IL-12 Plasmid, Delivered Via Intradermal or Intramuscular Electroporation in Healthy, HIV-Uninfected Adults

Who this might be right for
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 94
Not applicableStudy completedNCT05297747
What this trial is testing

Adrenomedullin Upregulation in Apical Periodontitis

Who this might be right for
Periapical Periodontitis
Istanbul Medipol University Hospital 174
Testing effectiveness (Phase 2)Study completedNCT00016289
What this trial is testing

Interleukin-12 in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Who this might be right for
Primary Peritoneal Cavity CancerRecurrent Ovarian Epithelial Cancer
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Ended earlyNCT01579318
What this trial is testing

Phase II Intratumoral IL12 Plasmid Electroporation in Cutaneous Lymphoma

Who this might be right for
Cutaneous T Cell Lymphomas (CTCL)Mycosis Fungoides (MF)
OncoSec Medical Incorporated 2
Testing effectiveness (Phase 2)Study completedNCT03366142
What this trial is testing

Ustekinumab (Anti-IL-12/23p40 Monoclonal Antibody) in Patients With Leukocyte Adhesion Deficiency Type 1 (LAD1) Who Have Inflammatory Pathology

Who this might be right for
LAD1
National Institute of Allergy and Infectious Diseases (NIAID) 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT04251117
What this trial is testing

GNOS-PV02 Personalized Neoantigen Vaccine, INO-9012 and Pembrolizumab in Subjects With Advanced HCC

Who this might be right for
HCC
Geneos Therapeutics 36
Early research (Phase 1)Looking for participantsNCT04471987
What this trial is testing

Safety and Early Signs of Efficacy of IL12-L19L19.

Who this might be right for
Advanced Solid TumorMetastatic Solid Tumor
Philogen S.p.A. 80
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