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Results for “Janus Kinase Inhibitor”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)UnknownNCT04878003
What this trial is testing

Study of KRT-232 or TL-895 in Janus Associated Kinase Inhibitor Treatment-Naïve Myelofibrosis

Who this might be right for
Primary Myelofibrosis (PMF)Post-Polycythemia Vera Myelofibrosis (Post-PV-MF)Post-Essential Thrombocythemia Myelofibrosis (Post-ET-MF)
Kartos Therapeutics, Inc. 52
Not applicableStudy completedNCT06449820
What this trial is testing

Janus Kinase Inhibitors for the Treatment of Acute Severe Ulcerative Colitis

Who this might be right for
Ulcerative ColitisInflammatory Bowel Diseases
Central Hospital, Nancy, France 36
Testing effectiveness (Phase 2)Looking for participantsNCT06715982
What this trial is testing

JAK Inhibitors for Solid Malignant Tumor Patients With Immune Checkpoint Inhibitors-related Dermatitis: A Open-lable, Single Arm, Phase IIa Trial

Who this might be right for
Immune Checkpoint Inhibitors (ICI)-Related Dermatitis
Shixiu Wu 35
Large-scale testing (Phase 3)Looking for participantsNCT06615050
What this trial is testing

Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

Who this might be right for
Graft-versus-host Disease (GVHD)
Incyte Corporation 572
Not applicableWithdrawnNCT04761978
What this trial is testing

Efficacy and Tolerance of JAK Inhibitors in ATU for Atopic Dermatitis

Who this might be right for
Dermatitis, Atopic
University Hospital, Lille
Large-scale testing (Phase 3)Study completedNCT01243944
What this trial is testing

Study of Efficacy and Safety in Polycythemia Vera Subjects Who Are Resistant to or Intolerant of Hydroxyurea: JAK Inhibitor INC424 (INCB018424) Tablets Versus Best Available Care: (The RESPONSE Trial)

Who this might be right for
Polycythemia Vera
Incyte Corporation 222
Large-scale testing (Phase 3)UnknownNCT05090410
What this trial is testing

Efficacy and Safety of Selective JAK 1 Inhibitor Filgotinib in Active Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate

Who this might be right for
Rheumatoid ArthritisJAK InhibitorIL-6 Inhibitor+2 more
Atsushi Kawakami 400
Testing effectiveness (Phase 2)Study completedNCT02426086
What this trial is testing

Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated With Janus Kinase (JAK) Inhibitor

Who this might be right for
Myelofibrosis
Geron Corporation 107
Testing effectiveness (Phase 2)Looking for participantsNCT07547930
What this trial is testing

Tofacitinib for Glucocorticoid-Resistant Moderate-to-Severe Thyroid Eye Disease

Who this might be right for
Thyroid Eye Disease, TEDGraves OphthalmopathyGraves Orbitopathy
The First Affiliated Hospital of Xiamen University 8
Testing effectiveness (Phase 2)Study completedNCT04402866
What this trial is testing

TD-0903 for ALI Associated With COVID-19

Who this might be right for
Acute Lung Injury (ALI) Associated With COVID-19Lung Inflammation Associated With COVID-19
Theravance Biopharma 235
Testing effectiveness (Phase 2)Ended earlyNCT03742973
What this trial is testing

Baricitinib (LY3009104) in Participants With Primary Biliary Cholangitis Who do Not Respond or Cannot Take UDCA

Who this might be right for
Primary Biliary Cholangitis
Eli Lilly and Company 2
Testing effectiveness (Phase 2)Study completedNCT04246372
What this trial is testing

Tofacitinib for Immune Skin Conditions in Down Syndrome

Who this might be right for
Down SyndromeAlopecia AreataAtopic Dermatitis / Eczema+3 more
University of Colorado, Denver 47
Early research (Phase 1)Study completedNCT04004663
What this trial is testing

Bioavailability Study of PF-06651600 Formulations in Healthy Participants

Who this might be right for
Healthy Volunteers
Pfizer 12
Testing effectiveness (Phase 2)Ended earlyNCT02718300
What this trial is testing

INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 74
Large-scale testing (Phase 3)UnknownNCT03662126
What this trial is testing

KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment

Who this might be right for
Primary Myelofibrosis (PMF)Post-Polycythemia Vera MF (Post-PV-MF)Post-Essential Thrombocythemia MF (Post-ET-MF)
Kartos Therapeutics, Inc. 385
Early research (Phase 1)Looking for participantsNCT06008808
What this trial is testing

Ruxolitinib With and Without CTLA-4 Ig Abatacept for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Who this might be right for
Graft Vs Host DiseaseGraft-versus-host-diseaseGraft Versus Host Disease
Washington University School of Medicine 41
Not applicableUnknownNCT05767775
What this trial is testing

Synovial and Adipose Tissue Composition in Overweight/Obese Patients With Active Rheumatoid Arthritis Under JAK/STAT Inhibition

Who this might be right for
Rheumatoid Arthritis
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 30
Post-approval studies (Phase 4)Not Yet RecruitingNCT07770646
What this trial is testing

A Pragmatic Trial of Interleukin-17 Inhibition Versus Janus Kinase Inhibition After Tumor Necrosis Factor-alpha Inhibitor Failure in Axial Spondyloarthritis

Who this might be right for
Axial Spondyloarthritis (AxSpA)
The University of Texas Health Science Center, Houston 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT07727889
What this trial is testing

A 24-Week Real-World Study of Upadacitinib in Moderate-to-Severe Hidradenitis Suppurativa

Who this might be right for
Hidradenitis Suppurativa (Acne Inversa)
Peking Union Medical College 50
Large-scale testing (Phase 3)Study completedNCT00952289
What this trial is testing

COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I Trial

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 309
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