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Results for “KIT Gene Mutation”

54 trials

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Showing 20 of 54 results

Not applicableLooking for participantsNCT06645236
What this trial is testing

DHF-20-1839-2: Clinical Performance Study Protocol for Therascreen® KRAS RGQ PCR Kit

Who this might be right for
Metastatic Colorectal Cancer (mCRC)
QIAGEN Gaithersburg, Inc 600
Not applicableUnknownNCT02661009
What this trial is testing

Human EGFR Mutations Quantitative Detection Kit (Real-time Fluorescent PCR Method)

Who this might be right for
Non Small Cell Lung CancerEGFR-TKI Resistant MutationEGFR-TKI Sensitizing Mutation
GenoSaber 1,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT06208748
What this trial is testing

SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST

Who this might be right for
Gastrointestinal Stromal TumorsGIST
Sarcoma Alliance for Research through Collaboration 40
Early research (Phase 1)Study completedNCT01531361
What this trial is testing

Vemurafenib With Sorafenib Tosylate or Crizotinib in Treating Patients With Advanced Malignancies With BRAF Mutations

Who this might be right for
Advanced Malignant NeoplasmBRAF Gene MutationMetastatic Malignant Neoplasm+2 more
M.D. Anderson Cancer Center 46
Testing effectiveness (Phase 2)UnknownNCT02501551
What this trial is testing

Regorafenib, C-kit Mutated Malignant Melanoma, 2nd Line Therapy

Who this might be right for
Melanoma
Yonsei University 36
Not applicableUnknownNCT01066286
What this trial is testing

Genome Wide SNP Array-based Approach to Detect Micro-cytogenetic Lesions and KIT Mutation to Improve Treatment Outcomes in Patients With Core-binding Factor Positive Acute Myeloid Leukemia

Who this might be right for
Myeloid Leukemia
Samsung Medical Center 100
Testing effectiveness (Phase 2)Study completedNCT00171912
What this trial is testing

Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes

Who this might be right for
Hypereosinophilic SyndromeSystemic MastocytosisChronic Myelomonocytic Leukemia+1 more
Novartis Pharmaceuticals 38
Testing effectiveness (Phase 2)Looking for participantsNCT05009927
What this trial is testing

Efficiency of Imatinib Treatment After 10 Years of Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) (Gist-Ten)

Who this might be right for
Metastatic Gastrointestinal Stromal Tumor (GIST)C-KIT MutationAdvanced Gastrointestinal Stromal Tumor (GIST)
Centre Leon Berard 50
Testing effectiveness (Phase 2)WithdrawnNCT02812693
What this trial is testing

Pembrolizumab and Imatinib in Patients With Locally Advanced/Metastatic Melanoma With c-KIT Mutation/Amplification

Who this might be right for
Stage IIIA Skin MelanomaStage IIIB Skin MelanomaStage IIIC Skin Melanoma+1 more
Joanne Jeter
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06765915
What this trial is testing

Avapritinib Maintenance for AML With KIT Mutations

Who this might be right for
AML, Adult
Ruijin Hospital 47
Not applicableUnknownNCT05895942
What this trial is testing

Exploring the Molecular Mechanism Based on KIT Mutation

Who this might be right for
GIST
Xijing Hospital 190
Large-scale testing (Phase 3)Study completedNCT00814073
What this trial is testing

Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis

Who this might be right for
Indolent Systemic Mastocytosis
AB Science 135
Not applicableLooking for participantsNCT06573073
What this trial is testing

Evaluation of Clinical Performance and IVD Test of LifeOS Digital PCR Liquid Biopsy Kits for EGFR T790M Mutation

Who this might be right for
Non Small Cell Lung CancerEGFR T790M
LifeOS Genomics Corporation 300
Testing effectiveness (Phase 2)Study completedNCT00881049
What this trial is testing

Trial of Imatinib (Gleevec®) in Selected Patients With Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Peking University 1
Testing effectiveness (Phase 2)UnknownNCT03171389
What this trial is testing

POETIG Trial - POnatinib After rEsisTance to Imatinib in GIST

Who this might be right for
GIST, MalignantKIT Exon 13 MutationKIT Gene Mutation
Sebastian Bauer 81
Not applicableLooking for participantsNCT07562542
What this trial is testing

Peripheral Blood KIT-D816V Mutation in Adult Systemic Mastocytosis

Who this might be right for
Systemic MastocytosisKIT-D816V Mutation
The First Affiliated Hospital of Soochow University 50
Not applicableStudy completedNCT05178030
What this trial is testing

The GALLOP-11 Study

Who this might be right for
Gastro-intestinal Stromal Tumors
University Medical Center Groningen 243
Testing effectiveness (Phase 2)Study completedNCT00831974
What this trial is testing

Efficacy of AB1010 in Patients With Systemic Indolent Mastocytosis

Who this might be right for
Mastocytosis
AB Science 23
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06772233
What this trial is testing

Regorafenib Combined With Envafolimab for Metastatic Gastrointestinal Stromal Tumors With Kit Gene Exon 17 Mutation That Failed Standard Treatment

Who this might be right for
Metastatic Gastrointestinal Stromal Tumors (GIST)
Peking University 100
Testing effectiveness (Phase 2)Study completedNCT01028222
What this trial is testing

AMNN107 in the Treatment of Metastatic and/or Inoperable Melanoma Harboring a c-Kit Mutation

Who this might be right for
Melanoma
Novartis Pharmaceuticals 55
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