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Results for “KIT Gene Mutation”

54 trials

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Showing 20 of 54 results

Testing effectiveness (Phase 2)Study completedNCT01028222
What this trial is testing

AMNN107 in the Treatment of Metastatic and/or Inoperable Melanoma Harboring a c-Kit Mutation

Who this might be right for
Melanoma
Novartis Pharmaceuticals 55
Testing effectiveness (Phase 2)UnknownNCT01541709
What this trial is testing

Imatinib Dose Escalation to 800 mg/Day in Korean Patients With Metastatic or Unresectable GIST Harboring KIT Exon 9 Mutation: KENEDI

Who this might be right for
Gastrointestinal Stromal Tumors
Asan Medical Center 23
Not applicableStudy completedNCT05178030
What this trial is testing

The GALLOP-11 Study

Who this might be right for
Gastro-intestinal Stromal Tumors
University Medical Center Groningen 243
Not applicableStudy completedNCT02503800
What this trial is testing

The Significance of Blood-tryptase and c-Kit Mutation in Insect Venom Immunotherapy

Who this might be right for
Hypersensitivity, ImmediateInsect Bites and StingsMastocytosis
Meir Medical Center 159
Large-scale testing (Phase 3)Ended earlyNCT01280565
What this trial is testing

Masitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-Kit

Who this might be right for
Metastatic Melanoma
AB Science 134
Testing effectiveness (Phase 2)Looking for participantsNCT06316960
What this trial is testing

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation

Who this might be right for
AML, ChildhoodRelapse/RecurrenceRefractory AML+2 more
Children's Hospital of Soochow University 50
Large-scale testing (Phase 3)Study completedNCT00814073
What this trial is testing

Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis

Who this might be right for
Indolent Systemic Mastocytosis
AB Science 135
Not applicableLooking for participantsNCT07255638
What this trial is testing

A Non-Interventional Study in Participants With Indolent Systemic Mastocytosis (ISM) in Germany

Who this might be right for
Indolent Systemic Mastocytosis
Blueprint Medicines Corporation 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT06208748
What this trial is testing

SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST

Who this might be right for
Gastrointestinal Stromal TumorsGIST
Sarcoma Alliance for Research through Collaboration 40
Large-scale testing (Phase 3)Not Yet RecruitingNCT05970900
What this trial is testing

Preoperative Imatinib Mesylate Combined With Rectal-sparing Surgery in Patients With c-KIT Gene-mutant Rectal GIST

Who this might be right for
Gastrointestinal Stromal Tumor of Rectum
Fujian Medical University Union Hospital 23
Testing effectiveness (Phase 2)Study completedNCT00171912
What this trial is testing

Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes

Who this might be right for
Hypereosinophilic SyndromeSystemic MastocytosisChronic Myelomonocytic Leukemia+1 more
Novartis Pharmaceuticals 38
Early research (Phase 1)Study completedNCT01531361
What this trial is testing

Vemurafenib With Sorafenib Tosylate or Crizotinib in Treating Patients With Advanced Malignancies With BRAF Mutations

Who this might be right for
Advanced Malignant NeoplasmBRAF Gene MutationMetastatic Malignant Neoplasm+2 more
M.D. Anderson Cancer Center 46
Not applicableLooking for participantsNCT06573073
What this trial is testing

Evaluation of Clinical Performance and IVD Test of LifeOS Digital PCR Liquid Biopsy Kits for EGFR T790M Mutation

Who this might be right for
Non Small Cell Lung CancerEGFR T790M
LifeOS Genomics Corporation 300
Testing effectiveness (Phase 2)Study completedNCT01266369
What this trial is testing

Masitinib in Patients With Mastocytosis With Handicap and Bearing the D816V Mutation

Who this might be right for
Mastocytosis
AB Science 21
Not applicableUnknownNCT01066286
What this trial is testing

Genome Wide SNP Array-based Approach to Detect Micro-cytogenetic Lesions and KIT Mutation to Improve Treatment Outcomes in Patients With Core-binding Factor Positive Acute Myeloid Leukemia

Who this might be right for
Myeloid Leukemia
Samsung Medical Center 100
Testing effectiveness (Phase 2)Study completedNCT01395121
What this trial is testing

A Trial Looking at Nilotinib to Treat Acral and Mucosal Melanoma Skin Cancer That Has Spread

Who this might be right for
Mucosal Lentiginous MelanomaAcral Lentiginous Malignant Melanoma
Institute of Cancer Research, United Kingdom 29
Not applicableLooking for participantsNCT07264959
What this trial is testing

An Observational Study in Participants With Indolent Systemic Mastocytosis (ISM)

Who this might be right for
Indolent Systemic Mastocytosis
Blueprint Medicines Corporation 150
Not applicableStudy completedNCT05347745
What this trial is testing

Therascreen® KRAS RGQ PCR Kit

Who this might be right for
Colo-rectal Cancer
QIAGEN Gaithersburg, Inc 219
Not applicableStudy completedNCT00336076
What this trial is testing

Molecular Mechanisms and Diagnosis of Mastocytosis

Who this might be right for
Mastocytosis
University of Michigan 136
Not applicableStudy completedNCT01505205
What this trial is testing

Study on the Evolution of Genes Mutation Related With Gastrointestinal Stromal Tumors

Who this might be right for
Full Gene Sequences of c-KIT、PDGFRA and DOG1 Are Analyzed With the Screening-sequencing ApproachInvestigate the Characteristics and Variations Associated With the Different Gene Mutations of c-KIT、PDGFRA and DOG1 in GIST Patients
Guangxi Medical University 60
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