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Results for “KRAS G12C Mutation Advanced Solid Tumor”

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Showing 20 of 0 results

Early research (Phase 1)Not Yet RecruitingNCT07542704
What this trial is testing

Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid Malignancies

Who this might be right for
Advanced Solid TumorsColorectal Cancer (CRC)Non-Small Cell Lung Cancer+3 more
Kumquat Biosciences Inc. 48
Testing effectiveness (Phase 2)Looking for participantsNCT07629960
What this trial is testing

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

Who this might be right for
Advanced Solid TumorNon-Small Cell Lung CancerColorectal Neoplasms+1 more
Blueprint Medicines Corporation 265
Early research (Phase 1)Active Not RecruitingNCT04449874
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

Who this might be right for
Non-Small Cell Lung CancerColorectal CancerAdvanced Solid Tumors
Genentech, Inc. 498
Testing effectiveness (Phase 2)Study completedNCT06208124
What this trial is testing

IMM-6-415 in RAS/RAF Mutant Solid Tumors

Who this might be right for
Advanced Solid Tumor (Phase 1)Pancreas AdenocarcinomaNon-small Cell Lung Cancer+1 more
Immuneering Corporation 30
Early research (Phase 1)Ended earlyNCT04892017
What this trial is testing

Study of Inlexisertib (DCC-3116) in Participants With RAS/MAPK Pathway Mutant Solid Tumors

Who this might be right for
Non-Small Cell Lung CancerAdvanced Solid TumorMetastatic Solid Tumor
Deciphera Pharmaceuticals, LLC 91
Testing effectiveness (Phase 2)Looking for participantsNCT07581912
What this trial is testing

Neoadjuvant Treatment of Fulzerasib Plus Cetuximab N01 in KRAS G12C Mutated Locally Advanced Colorectal Cancer With or Without Resectable Metastases

Who this might be right for
Colorectal CancerKRAS G12C Mutant Advanced Solid TumorsFulzerasib+1 more
Zhejiang University 40
Early research (Phase 1)Ended earlyNCT03114319
What this trial is testing

Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors

Who this might be right for
Advanced EGFR Mutant Non Small Cell LungCancer (NSCLC)KRAS G12-mutant NSCLCEsophageal Squamous Cell Cancer (SCC)+4 more
Novartis Pharmaceuticals 227
Testing effectiveness (Phase 2)Active Not RecruitingNCT04956640
What this trial is testing

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Who this might be right for
Carcinoma, Non-Small-Cell LungColorectal NeoplasmsEndometrial Neoplasms+3 more
Eli Lilly and Company 540
Early research (Phase 1)Active Not RecruitingNCT05485974
What this trial is testing

A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation

Who this might be right for
Lung CancerNon Small Cell Lung CancerColorectal Cancer+4 more
HUYABIO International, LLC. 44
Testing effectiveness (Phase 2)Active Not RecruitingNCT06166836
What this trial is testing

Evaluate the Safety and Efficacy of D-1553 Combined With IN10018 in KRAS G12C Mutant Solid Tumors

Who this might be right for
Solid Tumor
InxMed (Shanghai) Co., Ltd. 140
Early research (Phase 1)Active Not RecruitingNCT04185883
What this trial is testing

Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

Who this might be right for
Advanced Solid TumorsKirsten Rat Sarcoma (KRAS) pG12C Mutation
Amgen 610
Early research (Phase 1)Ended earlyNCT06130254
What this trial is testing

Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers

Who this might be right for
Advanced Solid TumorNon-small Cell Lung Cancers
M.D. Anderson Cancer Center 1
Early research (Phase 1)Looking for participantsNCT06659341
What this trial is testing

A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation

Who this might be right for
Advanced Solid Tumors Harboring KRAS G12C Mutation
Bayer 104
Testing effectiveness (Phase 2)Looking for participantsNCT05367778
What this trial is testing

Phase 1/2 Study of HS-10370 in Patients with Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Jiangsu Hansoh Pharmaceutical Co., Ltd. 176
Testing effectiveness (Phase 2)Looking for participantsNCT07468071
What this trial is testing

Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments

Who this might be right for
Locally Advanced or Metastatic KRAS G12C-mutated Non-small Cell Lung CancerAdvanced Solid Tumors Harboring the KRAS G12C Mutation
Novartis Pharmaceuticals 40
Early research (Phase 1)Study completedNCT04330664
What this trial is testing

Adagrasib in Combination With TNO155 in Patients With Cancer (KRYSTAL 2)

Who this might be right for
Advanced CancerMetastatic CancerMalignant Neoplastic Disease
Mirati Therapeutics Inc. 86
Testing effectiveness (Phase 2)Looking for participantsNCT07172919
What this trial is testing

A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation

Who this might be right for
Advanced Solid Tumors
Amgen 14
Early research (Phase 1)Study completedNCT04006301
What this trial is testing

First-in-Human Study of JNJ-74699157 in Participants With Tumors Harboring the KRAS G12C Mutation

Who this might be right for
NeoplasmsAdvanced Solid TumorsNon-small Cell Lung Cancer+1 more
Janssen Research & Development, LLC 10
Early research (Phase 1)Looking for participantsNCT06804824
What this trial is testing

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-159642 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Vividion Therapeutics, Inc. 220
Not applicableApproved For MarketingNCT05162443
What this trial is testing

Expanded Access of Adagrasib (MRTX849) in Patients With Advanced Solid Tumors Who Have a KRAS G12C Mutation

Who this might be right for
Advanced CancerMetastatic CancerMalignant Neoplasm
Bristol-Myers Squibb
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