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Results for “KRAS Wildtype”

114 trials

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Showing 20 of 114 results

Testing effectiveness (Phase 2)Study completedNCT01326000
What this trial is testing

RO5083945 in Combination With FOLFIRI Versus FOLFIRI Plus Cetuximab or FOLFIRI Alone as Second Line Treatment in Patients With Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 169
Testing effectiveness (Phase 2)Study completedNCT00779454
What this trial is testing

Combined Biological Treatment and Chemotherapy for Patients With Inoperable Cholangiocarcinoma

Who this might be right for
Cholangiocarcinoma
Vejle Hospital 72
Large-scale testing (Phase 3)Ended earlyNCT05223673
What this trial is testing

Phase 3 Study of Futuximab/Modotuximab in Combination With Trifluridine/Tipiracil Versus Trifluridine/Tipiracil Single Agent in Participants With Previously Treated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Institut de Recherches Internationales Servier 7
Large-scale testing (Phase 3)Looking for participantsNCT06750094
What this trial is testing

Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Who this might be right for
Colorectal Neoplasms
Janssen Research & Development, LLC 700
Testing effectiveness (Phase 2)Study completedNCT01229150
What this trial is testing

Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With Erlotinib in KRAS Wild Type Advanced Non-Small Cell Lung Cancer (NSCLC) and a Randomized Phase II Study of AZD6244 With Erlotinib in Mutant KRAS Adva...

Who this might be right for
Non Small Cell Lung Carcinoma
National Cancer Institute (NCI) 89
Post-approval studies (Phase 4)UnknownNCT02301962
What this trial is testing

Phase IV Panitumumab Study in Indian Subjects With Metastatic Colorectal Cancer

Who this might be right for
Cancer
Dr. Reddy's Laboratories Limited 58
Testing effectiveness (Phase 2)Study completedNCT02278133
What this trial is testing

Study of WNT974 in Combination With LGX818 and Cetuximab in Patients With BRAF-mutant Metastatic Colorectal Cancer (mCRC) and Wnt Pathway Mutations

Who this might be right for
Metastatic Colorectal Cancer
Array BioPharma 20
Not applicableStudy completedNCT01834014
What this trial is testing

Exploratory Study in Achievement of Improved Survival by Molecular Targeted Chemotherapy and Liver Resection for Not Optimally Resectable Colorectal Liver Metastases

Who this might be right for
Liver MetastasisColorectal Cancer
EPS Corporation 110
Testing effectiveness (Phase 2)UnknownNCT01144195
What this trial is testing

A Clinical Trial of Panitumumab in Combination With FOLFIRI Chemotherapy as Second Line Treatment in Subjects With Metastatic Colorectal Cancer Expressing Wild-type KRAS and Who Had Progressed ≥ 6 Months After the Last Dose of the First Line Chemotherapy

Who this might be right for
Metastatic Colorectal Cancer
Associacio catalana per a la recerca oncologica i les seves implicacions sanitaries i socials 80
Testing effectiveness (Phase 2)Study completedNCT02063529
What this trial is testing

FOLFOXIRI With or Without Cetuximab as First-line Treatment of Patients With Non-resectable Liver - Only Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Sun Yat-sen University 101
Testing effectiveness (Phase 2)UnknownNCT02583542
What this trial is testing

AZD2014 in Combination With Selumetinib in Patients With Advanced Cancers

Who this might be right for
Triple-Negative Breast CancerSquamous Cell Lung CancerNon-squamous Cell Lung Cancer With KRAS Mutations+1 more
Queen Mary University of London 118
Large-scale testing (Phase 3)Active Not RecruitingNCT06625320
What this trial is testing

Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

Who this might be right for
Pancreatic CancerPDACPDAC - Pancreatic Ductal Adenocarcinoma
Revolution Medicines, Inc. 500
Large-scale testing (Phase 3)Study completedNCT01550055
What this trial is testing

Study of CMAB009 to Treat KRAS Wild Type Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Shanghai Zhangjiang Biotechnology Limited Company 512
Not applicableStudy completedNCT04718038
What this trial is testing

Continuing Cetuximab Plus Chemotherapy After First Progression in Wild-type KRAS, NRAS and BRAF V600E Metastatic Colorectal Cancer

Who this might be right for
Wild-type KRAS,NRAS and BRAF V600E Metastatic Colorectal Cancer
Henan Cancer Hospital 60
Testing effectiveness (Phase 2)Ended earlyNCT01060423
What this trial is testing

TACE With Irinotecan Drug-eluting Beads and Intravenous (IV) Cetuximab in Refractory Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hans-Joachim Schmoll, MD 8
Testing effectiveness (Phase 2)UnknownNCT02450656
What this trial is testing

Afatinib and Selumetinib in Advanced KRAS Mutant and PIK3CA Wildtype Non-small Cell Lung Cancer

Who this might be right for
Colorectal NeoplasmsGastrointestinal NeoplasmsPancreatic Neoplasms+1 more
The Netherlands Cancer Institute 320
Testing effectiveness (Phase 2)Study completedNCT00885885
What this trial is testing

Safety and Efficacy Study of FOLFOX4+Panitumumab vs.FOLFIRI+Panitumumab in Subjects WT KRAS Colorectal Cancer and Liver-only Metastases

Who this might be right for
Colorectal Cancer
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) 80
Testing effectiveness (Phase 2)Study completedNCT01443377
What this trial is testing

Neoadjuvant Radiochemotherapy Combined With Panitumumab in Locally Advanced KRAS Wild-type Rectal Cancer

Who this might be right for
Rectal Cancer
National Center for Tumor Diseases, Heidelberg 48
Not applicableEnded earlyNCT01074333
What this trial is testing

An Observational Study of Erbitux® in Patients With Metastatic Colorectal Cancer (mCRC) Refractory to Irinotecan-containing Treatment

Who this might be right for
Colorectal Neoplasm
Merck KGaA, Darmstadt, Germany 146
Testing effectiveness (Phase 2)Study completedNCT01075048
What this trial is testing

ARQ 197 in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Daiichi Sankyo 131
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