Post-approval studies (Phase 4)Study completedNCT06410612What this trial is testingBlock and Periarticular Injection StudyWho this might be right forPain, Postoperative Washington University School of Medicine 174
Not applicableNot Yet RecruitingNCT07177573What this trial is testingVirtual Reality During Passive Motion After Knee SurgeryWho this might be right forTotal Knee Arthroplasty Manisa Celal Bayar University 102
Post-approval studies (Phase 4)UnknownNCT04314505What this trial is testingOpioid-Sparing Protocol Comparing With Opioid-based Protocol After Bilateral Total Knee ArthroplastyWho this might be right forKnee ReplacementPostoperative PainOpioid Use Taipei Veterans General Hospital, Taiwan 56
Post-approval studies (Phase 4)Study completedNCT02274870What this trial is testingLiposomal Bupivacaine for Post Operative Pain After Knee Replacement SurgeryWho this might be right forPost-operative Pain Northwell Health 65
Post-approval studies (Phase 4)Study completedNCT01991288What this trial is testingAnalgesic Efficacy of Saphenous Nerve Block in Total Knee ReplacementWho this might be right forPost Operative Pain Cork University Hospital 20
Not applicableUnknownNCT02607579What this trial is testingComparing Exparel & Ropivacaine for Pain Relief in Total Knee ArthroplastyWho this might be right forKnee Osteoarthritis Monmouth Medical Center 200
Post-approval studies (Phase 4)Study completedNCT00968578What this trial is testingEffects of Methylprednisolone After Total Knee ArthroplastyWho this might be right forPostoperative PainPostoperative Nausea and VomitingSleeping Quality+2 more Hvidovre University Hospital 48
Not applicableWithdrawnNCT04670042What this trial is testingUsing Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee SurgeryWho this might be right forInjury; Nerve, Peripheral, MultipleChronic Post-Procedural PainTotal Knee Arthroplasty+5 more Stanford University
Not applicableUnknownNCT06002724What this trial is testingFeasibility Study of Peripheral Venous Cannulation Pain in Predicting Acute Pain After Total Knee ArthroplastyWho this might be right forVenous Cannulation PainTotal Knee ArthroplastyMovement-evoked Pain+1 more RenJi Hospital 180
Not applicableStudy completedNCT05581836What this trial is testingThe Effect of Central Sensitization and Neuropathic Pain After Total Knee ArthroplastyWho this might be right forNeuropathic Pain The Catholic University of Korea 312
Very early researchStudy completedNCT03845881What this trial is testingTrial Comparing a Multi-Modal Pain Protocol With and Without Opioids Following Total Joint ArthroplastyWho this might be right forTotal Knee Arthroplasty Mayo Clinic 45
Testing effectiveness (Phase 2)Study completedNCT01731730What this trial is testingStudy to Evaluate Safety/Efficacy of a Single Pre-Op Dose of AYX1 Injection to Treat Pain After Knee Replacement SurgeryWho this might be right forPostsurgical Pain Adynxx, Inc. 102
Post-approval studies (Phase 4)Ended earlyNCT02570503What this trial is testingPostoperative Pain Control After Periarticular Injection During Total Knee ArthroplastyWho this might be right forOsteoarthritis, Knee Virginia Commonwealth University 64
Large-scale testing (Phase 3)Looking for participantsNCT07226076What this trial is testingMethadone in TKA for Post-op Pain and Opioid ReductionWho this might be right forPost Operative Pain Medical University of South Carolina 162
Post-approval studies (Phase 4)Study completedNCT01780389What this trial is testingOpen-label Milnacipran for Persistent Knee Pain One Year After Total Knee Arthroplasty (TKA)Who this might be right forKnee Pain After Total Knee ArthroplastyOsteoarthritis Pain Duke University 5
Testing effectiveness (Phase 2)Study completedNCT06955923What this trial is testingTrigger Point Injection in Reducing Pain Following Total Knee ArthroplastyWho this might be right forTrigger Point Pain, Myofascial David Grant U.S. Air Force Medical Center 11
Post-approval studies (Phase 4)Not Yet RecruitingNCT07140510What this trial is testingDinalbuphine Sebacate in Postoperative Pain Control After TKAWho this might be right forOsteo Arthritis of the KneeTotal Knee Anthroplasty Thammasat University 100
Not applicableActive Not RecruitingNCT05435092What this trial is testingClinical Correlation of TKA Alignment and Native Knee AnatomyWho this might be right forTotal Knee Arthroplasty (TKA) University Hospital, Basel, Switzerland 75
Not applicableStudy completedNCT00269529What this trial is testingIntraarticular Analgesia After Total Knee Arthroplasty, a Randomised StudyWho this might be right forArthroplasty, Replacement, Knee University of Aarhus 80
Post-approval studies (Phase 4)Study completedNCT04432428What this trial is testingSafety and Efficacy of Patient Controlled Analgesia Using the Sublingual Sufentanil Tablet System (SSTS) in a Fast Track Rehabilitation Program After Total Knee ArthroplastyWho this might be right forPostoperative Pain University Hospital, Ghent 90