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Results for “LDL-C”

293 trials

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Showing 20 of 293 results

Large-scale testing (Phase 3)Study completedNCT03399370
What this trial is testing

Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol

Who this might be right for
ASCVDElevated Cholesterol
The Medicines Company 1,561
Large-scale testing (Phase 3)Study completedNCT01516879
What this trial is testing

Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study

Who this might be right for
Hypercholesterolemia
Amgen 905
Early research (Phase 1)Study completedNCT05531097
What this trial is testing

Ascending Single-Dose and Multiple-Dose Study to Evaluate HSK31679 in Healthy Subjects and Subjects With Elevated LDL-C

Who this might be right for
HealthyElevated LDL-C
Haisco Pharmaceutical Group Co., Ltd. 96
Large-scale testing (Phase 3)Study completedNCT00551447
What this trial is testing

A Study Comparing Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Patients at Risk for Heart Disease (0653-023)(COMPLETED)

Who this might be right for
Coronary Disease
Organon and Co 616
Not applicableStudy completedNCT00931320
What this trial is testing

Investigation Into the RAtio of LDL-CHolestEroL to HDL-Cholesterol Improvement After Statin Treatment in Korean Patients

Who this might be right for
Dyslipidemias
AstraZeneca 3,000
Early research (Phase 1)Study completedNCT01437059
What this trial is testing

Trial to Evaluate Safety and Tolerability of ALN-PCS02 in Subjects With Elevated LDL-Cholesterol (LDL-C)

Who this might be right for
Elevated LDL-Cholesterol (LDL-C)
Alnylam Pharmaceuticals 32
Large-scale testing (Phase 3)Study completedNCT06005597
What this trial is testing

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHypercholesterolemiaFamilial Hypercholesterolemia+2 more
NewAmsterdam Pharma 407
Early research (Phase 1)Not Yet RecruitingNCT07777003
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HS-10582 in Healthy Subjects and Subjects With Mildly Elevated LDL-C Levels

Who this might be right for
Dyslipidemia
Jiangsu Hansoh Pharmaceutical Co., Ltd. 76
Post-approval studies (Phase 4)Looking for participantsNCT06501443
What this trial is testing

LATAM LOWERS LDL-C

Who this might be right for
Hypercholesterolaemia
Novartis Pharmaceuticals 520
Not applicableNot Yet RecruitingNCT07252388
What this trial is testing

EARLY: Educational Intervention to Improve Patient Awareness on Early LDL-C Lowering in Secondary Prevention

Who this might be right for
Acute Coronary SyndromesChronic Coronary Syndromes
Heart Care Foundation 240
Not applicableStudy completedNCT04887662
What this trial is testing

Happy Gut Study - Fermented Vegetables and Cardiovascular Biomarkers

Who this might be right for
Cardiovascular Diseases
University of North Florida 87
Large-scale testing (Phase 3)Not Yet RecruitingNCT07619118
What this trial is testing

A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Rosuvastatin on LDL-C in Patients With Hypercholesterolaemia

Who this might be right for
Hypercholesterolaemia
AstraZeneca 200
Early research (Phase 1)Study completedNCT05905068
What this trial is testing

Adult Subjects With Elevated Low-Density Lipoprotein-Cholesterol to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects

Who this might be right for
To Reduce the LDL-C Level in Hypercholesteremia Adult PatientsCombination for Subgroup High LDL-c Patients With Other Comorbidities
Ikaria Bioscience Pty Ltd 32
Post-approval studies (Phase 4)UnknownNCT03418974
What this trial is testing

Safety and Efficacy of Statins for Chinese Patients With Dyslipidemia

Who this might be right for
Dyslipidemias
Fudan University 10,000
Not applicableStudy completedNCT01245738
What this trial is testing

Effect of Statins on Lipid Levels Following the First Acute Coronary Event (MK-0000-204)

Who this might be right for
DyslipidemiasHypercholesterolemiaHypertriglyceridemia+2 more
Merck Sharp & Dohme LLC 635
Early research (Phase 1)UnknownNCT06239714
What this trial is testing

Evaluate SGB-3403 in Healthy Volunteers and Subjects With Elevated Low-Density Lipoprotein Cholesterol (LDL-C)

Who this might be right for
Hyperlipidemias
Suzhou Sanegene Bio Inc. 64
Post-approval studies (Phase 4)Not Yet RecruitingNCT07684469
What this trial is testing

Comparative Assessment of Inclisiran on Top of Standard of Care Versus Standard of Care Alone for LDL-C Evaluation in Acute Coronary Syndrome Patients in Saudi Arabia

Who this might be right for
Acute Coronary Syndrome
Novartis Pharmaceuticals 300
Post-approval studies (Phase 4)Study completedNCT05192941
What this trial is testing

Study of Efficacy, Safety, Tolerability and Quality of Life of Inclisiran (KJX839) vs Placebo, on Top of Ongoing Individually Optimized Lipid-lowering Therapy, in Participants With Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Novartis Pharmaceuticals 1,770
Large-scale testing (Phase 3)Study completedNCT05888103
What this trial is testing

Efficacy and Safety of Inclisiran as Monotherapy in Chinese Adults With Low or Moderate ASCVD Risk and Elevated Low-density Lipoprotein Cholesterol.

Who this might be right for
Primary Hypercholesterolemia or Mixed Dyslipidemia
Novartis Pharmaceuticals 207
Early research (Phase 1)Study completedNCT04774003
What this trial is testing

Study of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inclisiran in Chinese Participants With Elevated Serum LDL-C

Who this might be right for
Hyperlipidemia
Novartis Pharmaceuticals 40
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