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Results for “LOCALLY ADVANCED RECTAL CANCER”

706 trials

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Showing 20 of 706 results

Testing effectiveness (Phase 2)Looking for participantsNCT04165772
What this trial is testing

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

Who this might be right for
Rectal AdenocarcinomaClinical Stage: Stage II (T3-4, N-)Stage III (Any T, N+)+2 more
Memorial Sloan Kettering Cancer Center 200
Testing effectiveness (Phase 2)Ended earlyNCT05678257
What this trial is testing

NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal NeoplasmsColorectal Adenocarcinoma+2 more
NuCana plc 180
Not applicableUnknownNCT04273477
What this trial is testing

Radiomics-based Artificial Intelligence System to Predict Neoadjuvant Treatment Response in Rectal Cancer

Who this might be right for
Rectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University 100
Testing effectiveness (Phase 2)Looking for participantsNCT06698757
What this trial is testing

Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Yugui Lian 96
Large-scale testing (Phase 3)Looking for participantsNCT06791512
What this trial is testing

MFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC

Who this might be right for
Colorectal Cancer (CRC)pMMR/MSS Adenocarcinoma of the Colon or Rectum
Jun Huang 166
Early research (Phase 1)Active Not RecruitingNCT04906044
What this trial is testing

Total Neoadjuvant Treatment Plus PD-1 in Mid-Low Locally Advanced Rectal Cancer

Who this might be right for
TislelizumabLocally Advanced Rectal CancerTotal Neoadjuvant Treatment+1 more
The First Hospital of Jilin University 46
Not applicableStudy completedNCT04324567
What this trial is testing

Inflammation After Laparoscopic Robot-assisted Surgery for Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal CancerAbdominoperineal Resection
Oslo University Hospital 55
Testing effectiveness (Phase 2)Active Not RecruitingNCT04864067
What this trial is testing

No Operation After Short Course Radiotherapy Followed By Consolidation Chemotherapy In Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Servicio de Salud Metropolitano Sur Oriente 73
Large-scale testing (Phase 3)Looking for participantsNCT06207981
What this trial is testing

Phase III Study Evaluating Induction Chemotherapy Followed by Chemoradiotherapy Compared to Standard Chemoradiotherapy for Locally Advanced SCCA

Who this might be right for
Anal Cancer
Federation Francophone de Cancerologie Digestive 310
Large-scale testing (Phase 3)Study completedNCT01500993
What this trial is testing

Capecitabine in the Perioperative Treatment of Rectal Cancer

Who this might be right for
Rectal Cancer
Universitätsmedizin Mannheim 401
Testing effectiveness (Phase 2)Study completedNCT00022698
What this trial is testing

Capecitabine and Irinotecan in Treating Patients With Locally Advanced, Recurrent, or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 67
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06014944
What this trial is testing

Short-course Radiotherapy Combined With Furoquintinib and PD-1 Monoclonal Antibody

Who this might be right for
Rectal Cancer
Changhai Hospital 30
Not applicableUnknownNCT03824899
What this trial is testing

UGT1A1 Combined With Pharmacokinetics of SN-38 in CPT-11-based CRT in Patients With Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Fudan University 100
Large-scale testing (Phase 3)Study completedNCT01186081
What this trial is testing

Comparison of Preoperative and Postoperative Radiotherapy and Capecitabine in Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Asan Medical Center 240
Early research (Phase 1)Looking for participantsNCT07348211
What this trial is testing

First in Human Study of SIM0610 in Solid Tumors

Who this might be right for
Advanced Solid TumoursNon-Small Cell Lung CancerColorectal Cancer+2 more
Jiangsu Simcere Pharmaceutical Co., Ltd. 260
Testing effectiveness (Phase 2)Study completedNCT01227707
What this trial is testing

Avastin (Bevacizumab) Plus Xeloda (Capecitabine) in Patients With Locally Advanced Rectal Cancer.

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 43
Testing effectiveness (Phase 2)Active Not RecruitingNCT04715633
What this trial is testing

PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability High
Sun Yat-sen University 53
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07243938
What this trial is testing

Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET)

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Locally Advanced Gastric/Gastroesophageal Junction AdenocarcinomaMetastatic Colorectal Cancer (mCRC)+1 more
Tao Zhang 70
Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07297030
What this trial is testing

SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer

Who this might be right for
Rectal Cancer
Sun Yat-sen University 37
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