Not applicableActive Not RecruitingNCT03127709What this trial is testingMemory, Thinking, and Brain Imaging in Adults With HistiocytosisWho this might be right forHistiocytosis Memorial Sloan Kettering Cancer Center 13
Large-scale testing (Phase 3)Not Yet RecruitingNCT07626398What this trial is testingAll-Trans Retinoic Acid for the Treatment of Hemophagocytic LymphohistiocytosisWho this might be right forHemophagocytic Lymphohistiocytosis (HLH) Beijing Anzhen Hospital 30
Not applicableStudy completedNCT02854943What this trial is testingInvestigation of Ferritin in Critically Ill Patients With Hemophagocytic LymphohistiocytosisWho this might be right forHemophagocytic Lymphohistiocytosis (HLH)Macrophage Activation Syndrome (MAS)Hemophagocytic Syndromes Gunnar Lachmann 2,623
Large-scale testing (Phase 3)UnknownNCT04120090What this trial is testingRuxolitinib as a Salvage Therapy for Hemophagocytic LymphohistiocytosisWho this might be right forHemophagocytic Lymphohistiocytosis Beijing Friendship Hospital 80
Testing effectiveness (Phase 2)Study completedNCT01104025What this trial is testingHybrid Immunotherapy for Hemophagocytic LymphoHistiocytosisWho this might be right forHemophagocytic Lymphohistiocytosis Children's Hospital Medical Center, Cincinnati 31
Not applicableStudy completedNCT05687474What this trial is testingBaby Detect : Genomic Newborn ScreeningWho this might be right forCongenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more Centre Hospitalier Universitaire de Liege 6,824
Testing effectiveness (Phase 2)Looking for participantsNCT06160791What this trial is testingRuxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)Who this might be right forHemophagocytic Lymphohistiocytoses Jerry Lee, MD, MSc, MPhil 54
Large-scale testing (Phase 3)Not Yet RecruitingNCT06951971What this trial is testingDose-modified Emapalumab and Ruxolitinib (E-Ru) Regimens for Hemophagocytic LymphohistiocytosisWho this might be right forHemophagocytic Lymphohistiocytosis (HLH) The First Affiliated Hospital of Soochow University 30
Testing effectiveness (Phase 2)Ended earlyNCT02193867What this trial is testingClinical Study In Infants With Rapidly Progressive Lysosomal Acid Lipase DeficiencyWho this might be right forLysosomal Acid Lipase Deficiency Alexion Pharmaceuticals, Inc. 10
Testing effectiveness (Phase 2)Study completedNCT07034209What this trial is testingEvaluate the Efficacy, Safety, Tolerability, Pharmacokinetic Characteristics, and Immunogenicity of Plonmarlimab in Subjects With Rheumatic and Immunological Disease-associated Haemophagocytic Lymphohistiocytosis (HLH) (Also Known as Macrophage Activation Syndrome (MAS))Who this might be right forHemophagocytic Lymphohistiocytoses TJ Biopharma Co., Ltd. 18
Not applicableEnded earlyNCT01547143What this trial is testingPilot Study of Etoposide-based Therapy and Hematopoietic Cell Transplantation for Hemophagocytic LymphohistiocytosisWho this might be right forHemophagocytic Lymphohistiocytosis Asan Medical Center 12
Early research (Phase 1)Study completedNCT02939547What this trial is testingStudy of the Pharmacokinetics of Trappsol and Effects on Potential Biomarkers of Niemann-Pick C1 (NPC1)Who this might be right forNiemann-Pick Disease, Type C1 Cyclo Therapeutics, Inc. 13
Early research (Phase 1)Study completedNCT01917708What this trial is testingBone Marrow Transplant With Abatacept for Non-Malignant DiseasesWho this might be right forHurler SyndromeFanconi AnemiaGlanzmann Thrombasthenia+12 more Emory University 10
Testing effectiveness (Phase 2)Looking for participantsNCT05828069What this trial is testingA Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell HistiocytosisWho this might be right forRecurrent Langerhans Cell HistiocytosisRefractory Langerhans Cell Histiocytosis National Cancer Institute (NCI) 48
Testing effectiveness (Phase 2)UnknownNCT02061800What this trial is testingCD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell TransplantWho this might be right forChronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more Diane George 14
Not applicableUnknownNCT06332183What this trial is testingGWAS and EWAS in Patients With Erdheim-Chester DiseaseWho this might be right forErdheim-Chester Disease Augusto Vaglio 300
Not applicableLooking for participantsNCT05702502What this trial is testingAssessing the Presence of CT-DNA in Lymphoma Associated HLHWho this might be right forLymphomaHaemophagocytic Lymphohistiocytosis Nottingham University Hospitals NHS Trust 12
Not applicableStudy completedNCT05641103What this trial is testingPREDIGA 2: Spanish Acronym of "Educational and Diagnostic Project for Gaucher and ASMD"Who this might be right forGaucher DiseaseAcid SphingoMyelinase DeficiencyASMD+2 more Fundación Española de Hematología y Hemoterapía 122
Testing effectiveness (Phase 2)Ended earlyNCT01372228What this trial is testingPhase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic DisordersWho this might be right forHurler Syndrome (MPS I)Hurler-Scheie SyndromeHunter Syndrome (MPS II)+9 more Talaris Therapeutics Inc. 3
Large-scale testing (Phase 3)Study completedNCT03312751What this trial is testingStudy to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic LymphohistiocytosisWho this might be right forPrimary Hemophagocytic Lymphohistiocytosis Swedish Orphan Biovitrum 35