Post-approval studies (Phase 4)Study completedNCT03910621What this trial is testingSafety and Efficacy of Miglustat in Chinese NPC PatientsWho this might be right forNiemann-Pick Disease, Type C Actelion 17
Early research (Phase 1)Ended earlyNCT00002947What this trial is testingIndium In 111 Pentetreotide in Treating Patients With Refractory CancerWho this might be right forBrain and Central Nervous System TumorsChildhood Langerhans Cell HistiocytosisGastrointestinal Carcinoid Tumor+9 more Yale University 35
Testing effectiveness (Phase 2)Study completedNCT01395004What this trial is testingTest the Ability of and Safety of GSK2110183 in Treating Langerhans Cell HistiocytosisWho this might be right forLangerhans Cell Histiocytosis GlaxoSmithKline 17
Not applicableUnknownNCT05114304What this trial is testingPrevalence of Mood and Anxiety Disorders in Adult Patients With Pulmonary Langerhans Cell HistiocytosisWho this might be right forPulmonary Langerhans Cell Histiocytosis Assistance Publique - Hôpitaux de Paris 100
Not applicableLooking for participantsNCT05277272What this trial is testingINTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH)Who this might be right forHemophagocytic Lymphohistiocytoses Children's Hospital Medical Center, Cincinnati 200
Testing effectiveness (Phase 2)UnknownNCT04120519What this trial is testingThalidomide, Cyclophosphamide and Dexamethasone for Recurrent/Refractory Adult Langerhans Cell HistiocytosisWho this might be right forLangerhans Cell Histiocytosis Peking Union Medical College Hospital 20
Testing effectiveness (Phase 2)Study completedNCT03096782What this trial is testingUmbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or LymphomaWho this might be right forAccelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia+19 more M.D. Anderson Cancer Center 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT03155620What this trial is testingTargeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)Who this might be right forAdvanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+42 more National Cancer Institute (NCI) 1,377
Not applicableUnknownNCT06587191What this trial is testingEmapalumab Efficacy in Children With Primary Hemophagocytic LymphohistiocytosisWho this might be right forPrimary Hemophagocytic Lymphohistiocytosis Federal Research Institute of Pediatric Hematology, Oncology and Immunology 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652What this trial is testingEnsartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)Who this might be right forAdvanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more National Cancer Institute (NCI) 13
Not applicableLooking for participantsNCT06192576What this trial is testingA Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)Who this might be right forNiemann-Pick DiseasesAcid Sphingomyelinase Deficiency Sanofi 10
Testing effectiveness (Phase 2)UnknownNCT01473797What this trial is testingEvaluation of Efficacy and Tolerance of Cladribine in Symptomatic Pulmonary Langerhans Cell HistiocytosisWho this might be right forLangerhans Cell Histiocytosis of Lung Assistance Publique - Hôpitaux de Paris 10
Large-scale testing (Phase 3)UnknownNCT06038422What this trial is testingGTP Regimen in the Treatment of Refractory/Recurrent HLHWho this might be right forRefractoryRecurrenceHemophagocytic Lymphohistiocytosis Beijing Friendship Hospital 15
Early research (Phase 1)Active Not RecruitingNCT00710892What this trial is testingCASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide GeneWho this might be right forAcute Lymphoblastic LeukemiaNon-Hodgkin's LymphomaMyelodysplastic Syndrome+1 more Baylor College of Medicine 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT02523040What this trial is testingLenalidomide for Adult Histiocyte DisordersWho this might be right forLangerhans Cell Histiocytosis (LCH)Histiocytoses Erdheim-chester DiseaseHistiocytic Sarcoma (HS) Dana-Farber Cancer Institute 12
Testing effectiveness (Phase 2)Study completedNCT02385110What this trial is testingAlemtuzumab or Tocilizumab in Combination With Etoposide and Dexamethasone for the Treatment of Adult Patients With Hemophagocytic LymphohistiocytosisWho this might be right forLeukemia M.D. Anderson Cancer Center 18
Not applicableLooking for participantsNCT05992532What this trial is testingGammaGA: Prevalence of Acid Sphingomyelinase Deficiency Disease (ASMD) and Gaucher Disease in Patients With Monoclonal Gammopathies and/or Multiple MyelomaWho this might be right forGaucher DiseaseAcid SphingoMyelinase Deficiency Fundación Española de Hematología y Hemoterapía 210
Testing effectiveness (Phase 2)Study completedNCT03471143What this trial is testingStudy of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type CWho this might be right forNiemann-Pick Disease, Type C Washington University School of Medicine 4
Not applicableStudy completedNCT02665546What this trial is testingEvaluation of Exercise Capacity and Exercise Limitation in Patients With Pulmonary Langerhans Cell HistiocytosisWho this might be right forLangerhans Cell Histiocytosis InCor Heart Institute 35
Testing effectiveness (Phase 2)UnknownNCT03795909What this trial is testingRuxolitinib Combined With Dexamethasone for HLHWho this might be right forHemophagocytic Lymphohistiocytosis Capital Research Institute of Pediatrics 50