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Results for “Langerhans Cell Histiocytosis of Lung”

71 trials

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Showing 20 of 71 results

Large-scale testing (Phase 3)Looking for participantsNCT02670707
What this trial is testing

Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

Who this might be right for
Langerhans Cell Histiocytosis
Baylor College of Medicine 124
Testing effectiveness (Phase 2)Study completedNCT03526250
What this trial is testing

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Ewing Sarcoma+29 more
National Cancer Institute (NCI) 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT04195555
What this trial is testing

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Recurrent EpendymomaRecurrent Ewing SarcomaRecurrent Hepatoblastoma+30 more
National Cancer Institute (NCI) 3
Early research (Phase 1)UnknownNCT05477446
What this trial is testing

Safety and Efficacy of CD207 Targeted CAR-T Cell Therapy in Patients With R/R Langerhans Cell Histiocytosis

Who this might be right for
Langerhans Cell Histiocytosis
Beijing Friendship Hospital 12
Testing effectiveness (Phase 2)Ended earlyNCT04356690
What this trial is testing

Etoposide in Patients With COVID-19 Infection

Who this might be right for
COVID-19
Boston Medical Center 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT07204041
What this trial is testing

Efficacy and Safety of XTD Regimen (Selinexor, Thalidomide and Dexamethasone) in Adult Patients With Relapsed/Refractory LCH

Who this might be right for
Langerhans Cell Histiocytosis (LCH)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 40
Large-scale testing (Phase 3)Looking for participantsNCT07440290
What this trial is testing

DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.

Who this might be right for
Haematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+17 more
Cancer Research UK 30
Not applicableTemporarily pausedNCT05028621
What this trial is testing

Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms and Castleman Disease

Who this might be right for
Castleman's Disease (CD)Langerhans Cell Histiocytosis (LCH)Non-Langerhans-Cell Histiocytosis
Case Comprehensive Cancer Center 135
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Not applicableStudy completedNCT02608619
What this trial is testing

Uptake and Biodistribution of 18F-fluorocholine in Histiocytic Disorders by PET Imaging and Biopsy Measurement

Who this might be right for
Erdheim-Chester DiseaseLangerhans Cell HistiocytosisHistiocytic Disorders
Memorial Sloan Kettering Cancer Center 3
Early research (Phase 1)Enrolling By InvitationNCT06902792
What this trial is testing

Adebrelimab Combined With Trametinib in the Treatment of Refractory Recurrent Langerhans Cell Histiocytosis in Children and Adolescents

Who this might be right for
Histiocytosis, Langerhans-Cell
Second Affiliated Hospital of Wenzhou Medical University 6
Not applicableUnknownNCT00483925
What this trial is testing

Cardiovascular Risk Factors and LCH in Adults

Who this might be right for
Histiocytosis, Langerhans-Cell
Laikο General Hospital, Athens
Very early researchUnknownNCT05353179
What this trial is testing

Study on Pharmacokinetics of Meperizumab Injection and NUCALA® in Healthy Male Volunteers

Who this might be right for
Granulomatosis With PolyangiitisHemophagocytic Syndrome
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 88
Testing effectiveness (Phase 2)Study completedNCT00588536
What this trial is testing

Study of Sequential Administration of Oral 6-Thioguanine After Methotrexate in Patients With LCH

Who this might be right for
Langerhans Cell Histiocytosis
Memorial Sloan Kettering Cancer Center 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT02574728
What this trial is testing

Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors

Who this might be right for
Cancer
Emory University 46
Testing effectiveness (Phase 2)Active Not RecruitingNCT03698994
What this trial is testing

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Ependymal TumorRecurrent Ewing Sarcoma+33 more
National Cancer Institute (NCI) 20
Testing effectiveness (Phase 2)Study completedNCT03270020
What this trial is testing

Denosumab for the Treatment of Adult LCH

Who this might be right for
Langerhans Cell Histiocytosis
Hellenic Society for the Study of Bone Metabolism 10
Testing effectiveness (Phase 2)Study completedNCT00048373
What this trial is testing

Treatment of Resistant Langerhans Cell Histiocytosis With ENBREL

Who this might be right for
Histiocytosis, Langerhans-Cell
Baylor College of Medicine 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT02425904
What this trial is testing

Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis and LCH-related Disorders

Who this might be right for
Langerhans Cell Histiocytosis
Dana-Farber Cancer Institute 25
Testing effectiveness (Phase 2)WithdrawnNCT01796405
What this trial is testing

Clofarabine for Langerhans in Pedi

Who this might be right for
Langerhans Cell Histiocytosis
Dana-Farber Cancer Institute
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