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Results for “Lazertinib”

37 trials

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Showing 20 of 37 results

Testing effectiveness (Phase 2)Looking for participantsNCT06268210
What this trial is testing

Neoadjuvant Lazertinib With or Without Chemotherapy for Patients With EGFR-mutated Resectable Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Yonsei University 160
Testing effectiveness (Phase 2)Active Not RecruitingNCT05786430
What this trial is testing

Lazertinib+Pemetrexed/Carboplatin in Patients With EGFR Sensitizing Mutation Positive Recurrent or Metastatic Non-Small Cell Lung Cancer Failed to Prior Lazertinib

Who this might be right for
Non-small Cell Lung Cancer
Yonsei University 87
Testing effectiveness (Phase 2)UnknownNCT05477615
What this trial is testing

Lazertinib/Pemetrexed/Carboplatin After Osimertinib Failure in NSCLC With Brain Metastases

Who this might be right for
Non-small Cell Lung Cancer
Jin Hyoung Kang 28
Testing effectiveness (Phase 2)UnknownNCT05338619
What this trial is testing

Lazertinib as Consolidation Therapy in Patients With Locally Advanced, Unresectable, EGFR-Mutant Non-Small Cell Lung Cancer (Stage III) Following Chemoradiation Therapy

Who this might be right for
Non-small Cell Lung Cancer Stage IIIEGFR Positive Non-small Cell Lung CancerNon-squamous Non-small-cell Lung Cancer
Sung Yong Lee 77
Testing effectiveness (Phase 2)Looking for participantsNCT06156527
What this trial is testing

Phase II Study of LAZE rtiNib Alone Versus Lazertinib Plus bevaCizumab for NSCLC With EGFR + & Smoker

Who this might be right for
Lazertinib
National Cancer Center, Korea 120
Early research (Phase 1)Active Not RecruitingNCT04077463
What this trial is testing

Lazertinib as Monotherapy or in Combination With Amivantamab in Participants With Advanced Non-small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Janssen Research & Development, LLC 701
Testing effectiveness (Phase 2)UnknownNCT05326425
What this trial is testing

Lazertinib in Patients With NSCLC With Asymptomatic or Mild Symptomatic Brain Metastases After Failure of EGFR TKI.

Who this might be right for
Lung Neoplasms
Jin Hyoung Kang 40
Testing effectiveness (Phase 2)UnknownNCT05167851
What this trial is testing

The Safety and Efficacy of First-line Lazertinib and Locally Ablative Radiotherapy in Patients With Synchronous Oligo-metastatic EGFR-mutant Non-small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
Yonsei University 68
Early research (Phase 1)Study completedNCT05076877
What this trial is testing

Lazertinib (JNJ-73841937) in Healthy Participants

Who this might be right for
Healthy
Janssen Research & Development, LLC 20
Not applicableApproved For MarketingNCT04829422
What this trial is testing

Early Access Program of Lazertinib in Republic of Korea

Who this might be right for
Lung Cancer
Yuhan Corporation
Post-approval studies (Phase 4)Not Yet RecruitingNCT07469488
What this trial is testing

A Clinical Trial on the Outcomes of Comprehensive Enhanced Prophylaxis Management (CEPM) in Chinese Patients With EGFR-Mutated Advanced NSCLC Receiving Amivantamab-Based Regimens

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)VTE (Venous Thromboembolism)Rash Due to Epidermal Growth Factor Receptor Inhibitors+1 more
Shanghai Pulmonary Hospital, Shanghai, China 122
Testing effectiveness (Phase 2)Looking for participantsNCT06667076
What this trial is testing

Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Janssen Research & Development, LLC 480
Early research (Phase 1)Study completedNCT05112952
What this trial is testing

Evaluate the Effect of Hepatic Impairment on Lazertinib (JNJ-73841937)

Who this might be right for
Hepatic ImpairmentHealthy
Janssen Research & Development, LLC 16
Early research (Phase 1)Study completedNCT05896683
What this trial is testing

Lazertinib (JNJ-73841937) Tablet in Healthy Adult Participants

Who this might be right for
Healthy
Janssen Research & Development, LLC 72
Large-scale testing (Phase 3)Active Not RecruitingNCT05388669
What this trial is testing

Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer

Who this might be right for
Advanced or Metastatic Non-small Cell Lung Cancer
Janssen Research & Development, LLC 418
Testing effectiveness (Phase 2)UnknownNCT06020989
What this trial is testing

Lazertinib and Chemotherapy Combination in EGFR-mutant NSCLC Patients Without ctDNA Clearance After lead-in Lazertinib Monotherapy

Who this might be right for
Non Small Cell Lung Cancer
Yonsei University 129
Large-scale testing (Phase 3)Active Not RecruitingNCT04248829
What this trial is testing

Clinical Trial of YH25448(Lazertinib) as the First-line Treatment in Patients With EGFR Mutation Positive Locally Advanced or Metastatic NSCLC (LASER301)

Who this might be right for
Non-Small Cell Lung Cancer
Yuhan Corporation 393
Not applicableUnknownNCT05377788
What this trial is testing

Lazertinib Real-world Observational Study of in Pre-treated EGFR T790M Mutant With Advanced Non-small Cell Lung Cancer

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaEGFR T790M
Samsung Medical Center 900
Testing effectiveness (Phase 2)Active Not RecruitingNCT05463224
What this trial is testing

Lazertinib for NSCLC Harboring Activating EGFR Mutations in TKI naïve Patients

Who this might be right for
NSCLC
Se-Hoon Lee 150
Early research (Phase 1)Study completedNCT05742594
What this trial is testing

Four Different Oral Tablet Formulations of Lazertinib (JNJ-73841937) in Healthy Adult Participants

Who this might be right for
Healthy
Janssen Research & Development, LLC 64
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