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Results for “Leber's Congenital Amaurosis”

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Showing 16 of 0 results

Early research (Phase 1)Study completedNCT00481546
What this trial is testing

Phase I Trial of Gene Vector to Patients With Retinal Disease Due to RPE65 Mutations

Who this might be right for
Amaurosis of LeberRetinal Diseases
University of Pennsylvania 15
Testing effectiveness (Phase 2)Study completedNCT00749957
What this trial is testing

Phase 1/2 Safety and Efficacy Study of AAV-RPE65 Vector to Treat Leber Congenital Amaurosis

Who this might be right for
Leber Congenital Amaurosis
Beacon Therapeutics 12
Not applicableStudy completedNCT03597399
What this trial is testing

A Patient Registry Study for Patients Treated With Voretigene Neparvovec in US

Who this might be right for
Confirmed Biallelic RPE65 Mutation-associated Retinal Dystrophy
Spark Therapeutics, Inc. 87
Not applicableStudy completedNCT02970266
What this trial is testing

Genetic Decryption of Leber Congenital Amaurosis (LCA) in a Large Cohort of Independent Families.

Who this might be right for
Leber Congenital Amaurosis
Assistance Publique - Hôpitaux de Paris 659
Not applicableActive Not RecruitingNCT07026565
What this trial is testing

Psychotherapy Group for Parents of Children With LCA

Who this might be right for
Leber Congenital Amaurosis (LCA)
Instituto de Genética Ocular 40
Testing effectiveness (Phase 2)Study completedNCT03140969
What this trial is testing

Study to Evaluate QR-110 in Leber's Congenital Amaurosis (LCA) Due to the c.2991+1655A>G Mutation (p.Cys998X) in the CEP290 Gene

Who this might be right for
Leber's Congenital Amaurosis
Laboratoires Thea 11
Early research (Phase 1)Study completedNCT01014052
What this trial is testing

Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations

Who this might be right for
LCA (Leber Congenital Amaurosis)RP (Retinitis Pigmentosa)
QLT Inc. 32
Not applicableStudy completedNCT02575430
What this trial is testing

Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT

Who this might be right for
Leber Congenital Amaurosis (LCA)Retinitis Pigmentosa (RP)
QLT Inc. 59
Not applicableStudy completedNCT02714816
What this trial is testing

Natural History Study of Patients With Leber Congenital Amaurosis Associated With Mutations in RPE65

Who this might be right for
Leber Congenital Amaurosis
MeiraGTx UK II Ltd 37
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07681778
What this trial is testing

Safety and Tolerability of Subretinal OPGx-RDH12-1001 for LCA-Associated Inherited Retinal Degeneration (LCA-IRD)

Who this might be right for
Leber Congenital AmaurosisLeber Congenital Amaurosis (LCA)
Opus Genetics, Inc 10
Testing effectiveness (Phase 2)Study completedNCT00643747
What this trial is testing

Safety Study of RPE65 Gene Therapy to Treat Leber Congenital Amaurosis

Who this might be right for
Retinal Degeneration
University College, London 12
Testing effectiveness (Phase 2)Ended earlyNCT03913130
What this trial is testing

Extension Study to Study PQ-110-001 (NCT03140969)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
Laboratoires Thea 9
Not applicableStudy completedNCT03396042
What this trial is testing

Natural History Study of CEP290-Related Retinal Degeneration

Who this might be right for
BlindnessLeber Congenital Amaurosis 10Vision Disorders+5 more
Editas Medicine, Inc. 26
Large-scale testing (Phase 3)Active Not RecruitingNCT03913143
What this trial is testing

Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
ProQR Therapeutics 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT01208389
What this trial is testing

Phase 1 Follow-on Study of AAV2-hRPE65v2 Vector in Subjects With Leber Congenital Amaurosis (LCA) 2

Who this might be right for
Leber Congenital Amaurosis
Spark Therapeutics, Inc. 12
Not applicableNot Yet RecruitingNCT06024057
What this trial is testing

An Expanded Clinical Study Evaluating the AAV2-RPE65 Gene Therapy(LX101) in Patients With LCA

Who this might be right for
To Evaluate the Scaling Clinical Study of AAV2-RPE65 Gene Therapy Agent (LX101) in Patients With Congenital Amaurosis (LCA)
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 3