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Results for “Leptomeningeal Disease”

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Showing 20 of 0 results

Early research (Phase 1)Looking for participantsNCT07361705
What this trial is testing

Zorifertinib With Osimertinib for NSCLC With Meningeal Progression

Who this might be right for
Patients With Advanced Non-small Cell Lung Cancer With Meningeal Progression After Osimertinib Treatment
Alpha Biopharma (Jiangsu) Co., Ltd. 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT05305365
What this trial is testing

Study Assessing QBS72S For Treating Brain Metastases

Who this might be right for
Brain MetastasesBreast CancerLung Cancer+2 more
Stanford University 21
Early research (Phase 1)Active Not RecruitingNCT04250545
What this trial is testing

Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

Who this might be right for
Leptomeningeal NeoplasmMetastatic Lung Non-Small Cell CarcinomaMetastatic Malignant Neoplasm in the Brain+4 more
National Cancer Institute (NCI) 22
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Not applicableStudy completedNCT02071056
What this trial is testing

Circulating Tumor DNA in Cerebrospinal Fluid as an Early Biomarker of Leptomeningeal Metastasis (LM)

Who this might be right for
Leptomeningeal Metastasis
Dartmouth-Hitchcock Medical Center 5
Not applicableNot Yet RecruitingNCT07689721
What this trial is testing

CtDNA-Guided Intraventricular Therapy for CNS Malignancies

Who this might be right for
Leptomeningeal DiseaseGlioblastomaBrain Metastases+2 more
Alireza Mansouri 77
Testing effectiveness (Phase 2)Looking for participantsNCT07304739
What this trial is testing

Furmonertinib Combined With Intrathecal Chemotherapy and Stereotactic Radiotherapy (SRT) for EGFR-Mutated NSCLC Patients With Brain Parenchymal and Leptomeningeal Metastases

Who this might be right for
Non Small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital 30
Post-approval studies (Phase 4)Looking for participantsNCT06230055
What this trial is testing

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

Who this might be right for
HER2-negative Breast CancerLeptomeningeal Metastasis
Fudan University 37
Large-scale testing (Phase 3)Looking for participantsNCT06500481
What this trial is testing

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+2 more
NRG Oncology 115
Testing effectiveness (Phase 2)Study completedNCT04420598
What this trial is testing

DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease

Who this might be right for
Advanced Breast CancerHER2-positive Breast CancerBrain Metastases+1 more
MedSIR 41
Not applicableLooking for participantsNCT04988009
What this trial is testing

Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology

Who this might be right for
Central Nervous System NeoplasmLeptomeningeal NeoplasmMetastatic Malignant Neoplasm in the Brain+1 more
M.D. Anderson Cancer Center 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06861218
What this trial is testing

Cerebrospinal Fluid Cytology-guided Intrathecal Chemo-holiday Therapy for EGFR-positive NSCLC Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Metastases
Zhejiang Cancer Hospital 42
Testing effectiveness (Phase 2)UnknownNCT05385185
What this trial is testing

Clinical Observation of ICI Combined With Recombinant Human Endostatin on Leptomeningeal Metastasis of Lung Cancer

Who this might be right for
Leptomeningeal MetastasisImmune Checkpoint InhibitorEndostatin
Hebei Medical University 20
Not applicableLooking for participantsNCT07398599
What this trial is testing

Double-Dose Third-Generation EGFR-TKI Plus Bevacizumab and Intrathecal Chemotherapy for Refractory Leptomeningeal Metastatic NSCLC: A Phase II Study

Who this might be right for
Leptomeningeal MetastasisLung Neoplasms, Non-Small Cell Lung Cancer
Second Affiliated Hospital of Nanchang University 30
Early research (Phase 1)Study completedNCT02423525
What this trial is testing

Safety Study of Afatinib for Brain Cancer

Who this might be right for
Brain Cancer
Santosh Kesari 24
Testing effectiveness (Phase 2)Ended earlyNCT03091478
What this trial is testing

Pembrolizumab in Patients With Leptomeningeal Disease

Who this might be right for
Patients With Leptomeningeal Disease
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 13
Early research (Phase 1)Ended earlyNCT00477503
What this trial is testing

Nuclear Imaging of Human CSF Flow Using Ga-67 Citrate and In-111 DTPA

Who this might be right for
Central Nervous System TumorsBrain Tumors
M.D. Anderson Cancer Center 1
Testing effectiveness (Phase 2)Active Not RecruitingNCT00338377
What this trial is testing

Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma

Who this might be right for
Melanoma
M.D. Anderson Cancer Center 1,230
Testing effectiveness (Phase 2)Study completedNCT03507244
What this trial is testing

Concurrent Intrathecal-pemetrexed and Involved-field Radiotherapy for Leptomeningeal Metastasis From Solid Tumors

Who this might be right for
Leptomeningeal Metastasis
The First Hospital of Jilin University 34
Early research (Phase 1)Study completedNCT00416923
What this trial is testing

Intrathecal Rituximab in Treating Patients With Recurrent CNS Lymphoma

Who this might be right for
Brain and Central Nervous System TumorsLymphoma
University of California, San Francisco 10
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