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Results for “Leptomeningeal Disease”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT00005842
What this trial is testing

Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer

Who this might be right for
Cancer
National Cancer Institute (NCI) 24
Not applicableUnknownNCT04778800
What this trial is testing

A Dose Exploration Study of Almonertinib for EGFRm NSCLC Patients With Brain/Leptomeningeal Metastasis (ARTISTRY)

Who this might be right for
NSCLCBrain MetastasesLeptomeningeal Metastasis
Henan Cancer Hospital 60
Early research (Phase 1)Ended earlyNCT03711422
What this trial is testing

Afatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC

Who this might be right for
Non-small Cell Lung CancerLeptomeningeal DiseaseCentral Nervous System Metastases
National Cancer Centre, Singapore 2
Not applicableStudy completedNCT04178343
What this trial is testing

Tomotherapy for Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Metastasis
Chinese Academy of Medical Sciences 103
Not applicableLooking for participantsNCT05746325
What this trial is testing

Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Leptomeninges+2 more
Mayo Clinic 5
Testing effectiveness (Phase 2)Looking for participantsNCT06016387
What this trial is testing

Tucatinib, Trastuzumab and Capecitabine With Brain and/or Spinal Radiotherapy (XRT) in Patients With HER2+, HER2 Mutated and/or HER2-amplified Metastatic Breast Cancer and Leptomeningeal Disease: A Multi-centre Phase II, Single Arm Feasibility Study

Who this might be right for
HER2-positive Breast CancerLMD
Sunnybrook Health Sciences Centre 30
Testing effectiveness (Phase 2)Study completedNCT00005811
What this trial is testing

Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment

Who this might be right for
AIDS-related Diffuse Large Cell LymphomaAIDS-related Diffuse Mixed Cell LymphomaAIDS-related Diffuse Small Cleaved Cell Lymphoma+17 more
National Cancer Institute (NCI) 77
Early research (Phase 1)Active Not RecruitingNCT04192981
What this trial is testing

GDC-0084 With Radiation Therapy for People With PIK3CA-Mutated Solid Tumor Brain Metastases or Leptomeningeal Metastases

Who this might be right for
Brain MetastasesLeptomeningeal Metastasis
Memorial Sloan Kettering Cancer Center 21
Not applicableLooking for participantsNCT06399926
What this trial is testing

Efficacy and Safety of Intraventricule Pemetrexed Disodium Administered Via Ommaya Reservoir

Who this might be right for
Leptomeningeal MetastasisLung Cancer
Xiangya Hospital of Central South University 64
Early research (Phase 1)Study completedNCT02228369
What this trial is testing

Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors, AZD3759 or AZD9291, in Patients Who Have Advanced Non-Small Cell Lung Cancer

Who this might be right for
EGFR Mutation Positive Advanced Non Small Cell Lung Cancer
AstraZeneca 108
Early research (Phase 1)Ended earlyNCT00515788
What this trial is testing

DepoCyt Plus Temozolomide in Patients With Neoplastic Meningitis

Who this might be right for
Neoplastic Meningitis
M.D. Anderson Cancer Center 11
Post-approval studies (Phase 4)Study completedNCT00029523
What this trial is testing

DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor

Who this might be right for
Meningeal Neoplasms
Pacira Pharmaceuticals, Inc 100
Testing effectiveness (Phase 2)Study completedNCT00445965
What this trial is testing

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

Who this might be right for
Brain and Central Nervous System TumorsIntraocular MelanomaLung Cancer+7 more
Memorial Sloan Kettering Cancer Center 78
Testing effectiveness (Phase 2)Looking for participantsNCT04923126
What this trial is testing

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

Who this might be right for
Low-Grade GliomaRecurrent Low-Grade GliomaProgressive Low-Grade Glioma
St. Jude Children's Research Hospital 132
Not applicableStudy completedNCT00949741
What this trial is testing

Observational Study for the Cytofluorimetric Analysis of Cerebrospinal Fluid in Non-Hodgkin's Lymphoma Patients

Who this might be right for
Diffuse Large Cell LymphomaLymphoblastic LymphomaBurkitt's Lymphoma
Gruppo Italiano Multiregionale per lo studio dei Linfomi e delle Leucemie 175
Testing effectiveness (Phase 2)UnknownNCT05813522
What this trial is testing

Furmonertinib in Patients With Leptomeningeal Metastases Associated With EGFR Mutated NSCLC

Who this might be right for
Non Small Cell Lung Cancer
First Affiliated Hospital of Zhejiang University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07833657
What this trial is testing

Combined Intrathecal and Systemic Therapy With Trastuzumab Rezetecan for Leptomeningeal Metastases

Who this might be right for
Leptomeningeal MetastasesSolid Tumors
Jiuda Zhao 28
Not applicableNot Yet RecruitingNCT07659652
What this trial is testing

Quality of Life for Patients With Breast Cancer Brain Metastases and Leptomeningeal Disease

Who this might be right for
Breast Cancer, Quality of LifeBreast Cancer, MetastaticBreast Cancer, Metastatic Breast Cancer+2 more
University of California, San Francisco 200
Early research (Phase 1)Active Not RecruitingNCT03423628
What this trial is testing

Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Who this might be right for
Recurrent Glioblastoma MultiformePrimary Glioblastoma MultiformeBrain Neoplasms, Malignant+1 more
AstraZeneca 159
Testing effectiveness (Phase 2)Looking for participantsNCT06809517
What this trial is testing

Intrathecal PD-1/VEGF Bispecific Antibody Plus Pemetrexed for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal MetastasisIntrathecal Drug Delivery
Guangzhou Medical University 34
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