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Results for “Leptomeningeal Neoplasm”

169 trials

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Showing 20 of 169 results

Testing effectiveness (Phase 2)Study completedNCT02939300
What this trial is testing

Ipilimumab and Nivolumab in Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Carcinomatosis
Massachusetts General Hospital 18
Testing effectiveness (Phase 2)Looking for participantsNCT06728865
What this trial is testing

Evaluation of the Efficacy and Safety of Furmonertinib Combined with Bevacizumab As First-Line Treatment for EGFR-Positive Non-Small Cell Lung Cancer with Brain Metastases: a Single-Arm, Open-Label, Prospective Phase II Clinical Study

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)EGFR Mutation-Positive Lung CancerBrain Metastases+2 more
Li-kun Chen 70
Early research (Phase 1)Study completedNCT00006246
What this trial is testing

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorLeukemia+4 more
Pediatric Brain Tumor Consortium 28
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Not applicableUnknownNCT02607605
What this trial is testing

A Prospective, Observational Trial on the Diagnostic and Prognostic of LM

Who this might be right for
Lung NeoplasmsMeningeal Carcinomatosis
Sun Yat-sen University 10
Testing effectiveness (Phase 2)Looking for participantsNCT06810804
What this trial is testing

A Phase IIa Study to Evaluate NBQ72S

Who this might be right for
Breast Cancer
Nantong Bencao Quadriga Medical Technology Co. Ltd. 10
Early research (Phase 1)Active Not RecruitingNCT03696030
What this trial is testing

HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases

Who this might be right for
Malignant NeoplasmMetastatic Malignant Neoplasm in the BrainMetastatic Malignant Neoplasm in the Leptomeninges+2 more
City of Hope Medical Center 24
Early research (Phase 1)Study completedNCT00025311
What this trial is testing

Topotecan in Treating Patients With Recurrent, Progressive, or Refractory Cancer That is Metastatic to the Lining Around the Brain

Who this might be right for
Brain and Central Nervous System Tumors
NYU Langone Health
Not applicableLooking for participantsNCT04988009
What this trial is testing

Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology

Who this might be right for
Central Nervous System NeoplasmLeptomeningeal NeoplasmMetastatic Malignant Neoplasm in the Brain+1 more
M.D. Anderson Cancer Center 200
Early research (Phase 1)Ended earlyNCT00512460
What this trial is testing

RTA 744 Injection in Patients With Leptomeningeal Disease

Who this might be right for
Neoplastic MeningitisSolid TumorLymphoma+2 more
M.D. Anderson Cancer Center 7
Not applicableStudy completedNCT01713699
What this trial is testing

Circulating Tumor Cells and Cytology in Cerebrospinal Fluid of Patients Clinically Suspected for Leptomeningeal Metastases

Who this might be right for
Meningeal Carcinomatosis
The Netherlands Cancer Institute 146
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06971406
What this trial is testing

High-Dose Firmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed in the Treatment of EGFR-Mutated Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Who this might be right for
Non Small Cell Lung CancerEGFR MutationLeptomeningeal Metastases+1 more
Qiming Wang 100
Not applicableLooking for participantsNCT06304441
What this trial is testing

Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer

Who this might be right for
Leptomeningeal Metastasis
Guangzhou Medical University 100
Testing effectiveness (Phase 2)Study completedNCT00450866
What this trial is testing

Epothilone B in Treating Patients With CNS Metastases From Breast Cancer

Who this might be right for
Breast CancerMetastatic Cancer
David Peereboom, MD 55
Testing effectiveness (Phase 2)UnknownNCT04833205
What this trial is testing

Clinical Efficacy and Safety of EGFR-TKI Combined With Nimotuzumab in the Treatment of Leptomeningeal Metastases From Lung Cancer

Who this might be right for
Leptomeningeal MetastasisLung Cancer
Hui Bu 30
Early research (Phase 1)Not Yet RecruitingNCT07199413
What this trial is testing

Allogeneic, Antigen-Presenting, GM-CSF-secreting, SV-BR-1-GM Whole Cell-Therapeutic Vaccine and Immunotherapy: A Phase I Pilot Safety and Feasibility Study for Solid Tumor Patients With CNS Metastases

Who this might be right for
Brain MetastasesLeptomeningeal Metastasis
Medical College of Wisconsin 20
Not applicableEnded earlyNCT05414123
What this trial is testing

A Therapy Treatment Response Trial in Patients With Leptomeningeal Metastases ((LM) Using CNSide

Who this might be right for
Leptomeningeal MetastasisLeptomeningeal DiseaseLeptomeningeal Neoplasms+2 more
Biocept, Inc. 40
Not applicableLooking for participantsNCT07348965
What this trial is testing

Pulsatile High-dose Furmonertinib in EGFR-mutant NSCLC With Leptomeningeal Metastasis

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)Leptomeningeal MetastasisFurmonertinib+1 more
Guangzhou University of Traditional Chinese Medicine 42
Testing effectiveness (Phase 2)Looking for participantsNCT06462092
What this trial is testing

Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer

Who this might be right for
Leptomeningeal Metastases
Guangzhou Medical University 34
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07177950
What this trial is testing

A Two-cohort Study of SHR-A1811 in the Treatment of HER2-positive Breast Cancer With Brain Metastases

Who this might be right for
Breast CancerBrain MetastasesLeptomeningeal Metastasis
Peking University Cancer Hospital & Institute 51
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