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Results for “Leptomeningeal Neoplasm”

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Showing 20 of 0 results

Early research (Phase 1)Looking for participantsNCT07361705
What this trial is testing

Zorifertinib With Osimertinib for NSCLC With Meningeal Progression

Who this might be right for
Patients With Advanced Non-small Cell Lung Cancer With Meningeal Progression After Osimertinib Treatment
Alpha Biopharma (Jiangsu) Co., Ltd. 42
Early research (Phase 1)Ended earlyNCT00512460
What this trial is testing

RTA 744 Injection in Patients With Leptomeningeal Disease

Who this might be right for
Neoplastic MeningitisSolid TumorLymphoma+2 more
M.D. Anderson Cancer Center 7
Testing effectiveness (Phase 2)Study completedNCT02336451
What this trial is testing

A Phase II Study to Evaluate the Efficacy and Safety of Oral Ceritinib in Patients With ALK-positive NSCLC Metastatic to the Brain and/or to Leptomeninges

Who this might be right for
ALK-positive Non-small Cell Lung Cancer
Novartis Pharmaceuticals 156
Testing effectiveness (Phase 2)Looking for participantsNCT05805631
What this trial is testing

Intrathecal Pemetrexed for Leptomeningeal Metastasis in EGFR-Mutant NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell LungEpidermal Growth Factor ReceptorLeptomeningeal Metastasis
Taipei Veterans General Hospital, Taiwan 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT00338377
What this trial is testing

Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma

Who this might be right for
Melanoma
M.D. Anderson Cancer Center 1,230
Testing effectiveness (Phase 2)Looking for participantsNCT06462092
What this trial is testing

Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer

Who this might be right for
Leptomeningeal Metastases
Guangzhou Medical University 34
Early research (Phase 1)Study completedNCT02228369
What this trial is testing

Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors, AZD3759 or AZD9291, in Patients Who Have Advanced Non-Small Cell Lung Cancer

Who this might be right for
EGFR Mutation Positive Advanced Non Small Cell Lung Cancer
AstraZeneca 108
Early research (Phase 1)Ended earlyNCT00527410
What this trial is testing

A Safety Study of RTA 744 in Recurrent, Progressive or Refractory Neoplastic Meningitis

Who this might be right for
Leptomeningeal Carcinomatosis
Biogen 9
Testing effectiveness (Phase 2)Looking for participantsNCT07694986
What this trial is testing

Trial of Therapies With IT cDC1s Combined w/ IT Trastuzamab for Her+ or IT Nivolumab for Her- BC LMD

Who this might be right for
Breast CancerLeptomeningeal Disease
H. Lee Moffitt Cancer Center and Research Institute 30
Not applicableNot Yet RecruitingNCT07659652
What this trial is testing

Quality of Life for Patients With Breast Cancer Brain Metastases and Leptomeningeal Disease

Who this might be right for
Breast Cancer, Quality of LifeBreast Cancer, MetastaticBreast Cancer, Metastatic Breast Cancer+2 more
University of California, San Francisco 200
Not applicableLooking for participantsNCT06399926
What this trial is testing

Efficacy and Safety of Intraventricule Pemetrexed Disodium Administered Via Ommaya Reservoir

Who this might be right for
Leptomeningeal MetastasisLung Cancer
Xiangya Hospital of Central South University 64
Testing effectiveness (Phase 2)UnknownNCT05385185
What this trial is testing

Clinical Observation of ICI Combined With Recombinant Human Endostatin on Leptomeningeal Metastasis of Lung Cancer

Who this might be right for
Leptomeningeal MetastasisImmune Checkpoint InhibitorEndostatin
Hebei Medical University 20
Not applicableLooking for participantsNCT06146010
What this trial is testing

Non Interventional German Leptomeningeal Disease Register

Who this might be right for
Meningeal NeoplasmsLeptomeningeal Disease
University Hospital Tuebingen 50
Testing effectiveness (Phase 2)Study completedNCT01325207
What this trial is testing

Intrathecal Trastuzumab for Leptomeningeal Metastases in HER2+ Breast Cancer

Who this might be right for
Breast Cancer
Northwestern University 34
Early research (Phase 1)Not Yet RecruitingNCT07702305
What this trial is testing

Safety and Efficacy of Intrathecal Sacituzumab Tirumotecan for Leptomeningeal Metastasis in EGFR-TKI-Resistant Non-Small Cell Lung Cancer

Who this might be right for
EGFR-TKI-resistant Non-small Cell Lung Cancer With Leptomeningeal Metastasis
Henan Cancer Hospital 15
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07751744
What this trial is testing

Phase 1/2 Study Evaluating the Safety, PK/PD, and Clinical Activity of Oral JBI-778 in Patients With Brain Metastases, Leptomeningeal Disease, or Recurrent High Grade Glioma

Who this might be right for
Brain Metastases From Solid TumorsLeptomeningeal DiseaseHigh Grade Glioma (HGG)+1 more
Jubilant Therapeutics Inc. 113
Post-approval studies (Phase 4)UnknownNCT04356222
What this trial is testing

Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal MetastasisDurvalumab
Hui Bu 30
Testing effectiveness (Phase 2)Study completedNCT00450866
What this trial is testing

Epothilone B in Treating Patients With CNS Metastases From Breast Cancer

Who this might be right for
Breast CancerMetastatic Cancer
David Peereboom, MD 55
Early research (Phase 1)Ended earlyNCT03711422
What this trial is testing

Afatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC

Who this might be right for
Non-small Cell Lung CancerLeptomeningeal DiseaseCentral Nervous System Metastases
National Cancer Centre, Singapore 2
Early research (Phase 1)Study completedNCT00006246
What this trial is testing

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorLeukemia+4 more
Pediatric Brain Tumor Consortium 28
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