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Results for “Lewy Body Parkinson Disease”

376 trials

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Showing 20 of 376 results

Large-scale testing (Phase 3)Looking for participantsNCT06989112
What this trial is testing

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Who this might be right for
Endometrial Cancer
AstraZeneca 600
Testing effectiveness (Phase 2)Study completedNCT03305809
What this trial is testing

LY3154207 in Participants With Dementia Due to Lewy Body Dementia (LBD) Associated With Idiopathic Parkinson's Disease (PD) or Dementia With Lewy Bodies (DLB)

Who this might be right for
Lewy Body Dementia
Eli Lilly and Company 344
Early research (Phase 1)Study completedNCT02054806
What this trial is testing

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-028/KEYNOTE-28)

Who this might be right for
Solid Tumor
Merck Sharp & Dohme LLC 477
Testing effectiveness (Phase 2)Study completedNCT03631407
What this trial is testing

Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 41
Large-scale testing (Phase 3)Active Not RecruitingNCT04246177
What this trial is testing

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Who this might be right for
Carcinoma, Hepatocellular
Merck Sharp & Dohme LLC 480
Early research (Phase 1)Study completedNCT04208152
What this trial is testing

A First-in-Human Study of Single and Multiple Doses of anle138b in Healthy Subjects

Who this might be right for
Healthy Volunteers
MODAG GmbH 68
Not applicableActive Not RecruitingNCT06389032
What this trial is testing

PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia

Who this might be right for
Lewy Body DementiaParkinson Disease DementiaDementia With Lewy Bodies+1 more
Rush University Medical Center 622
Not applicableStudy completedNCT01339130
What this trial is testing

Assessment of Social-emotional Functioning in Neurological Diseases

Who this might be right for
Alzheimer DiseaseStrokeParkinson's Disease+2 more
Centre Hospitalier Universitaire, Amiens 177
Large-scale testing (Phase 3)Active Not RecruitingNCT03711032
What this trial is testing

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

Who this might be right for
High-risk Non-muscle Invasive Bladder Cancer
Merck Sharp & Dohme LLC 1,397
Not applicableUnknownNCT04886193
What this trial is testing

FLOT Combined With PD-1 in the First-line Treatment of Patients With Advanced Gastric Cancer and Peritoneal Metastasis

Who this might be right for
ChemotherapyGastric Cancer
Guangdong Provincial Hospital of Traditional Chinese Medicine 20
Large-scale testing (Phase 3)Active Not RecruitingNCT03553836
What this trial is testing

Safety and Efficacy of Pembrolizumab Compared to Placebo in Resected High-risk Stage II Melanoma (MK-3475-716/KEYNOTE-716)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 976
Not applicableLooking for participantsNCT06529744
What this trial is testing

Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling

Who this might be right for
DementiaAlzheimer DiseaseDementia With Lewy Bodies+7 more
University Health Network, Toronto 500
Not applicableLooking for participantsNCT06629207
What this trial is testing

Artificial Intelligence in Molecular Imaging: Predicting Parkinson's Risk in REM Sleep Behavior Disorder

Who this might be right for
Parkinson DiseaseREM Sleep Behavior DisorderDementia, Lewy Body
Insel Gruppe AG, University Hospital Bern 20
Large-scale testing (Phase 3)Study completedNCT01866319
What this trial is testing

Study to Evaluate the Safety and Efficacy of Two Different Dosing Schedules of Pembrolizumab (MK-3475) Compared to Ipilimumab in Participants With Advanced Melanoma (MK-3475-006/KEYNOTE-006)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 834
Not applicableEnded earlyNCT00745030
What this trial is testing

Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and Parkinsonism

Who this might be right for
REM Behavior DisorderParkinsonism
Northwestern University 3
Not applicableUnknownNCT03917537
What this trial is testing

WGA in Platinum-refractory HNSCC Underwent Nivolumab

Who this might be right for
HNSCC
Chang Gung Memorial Hospital 80
Large-scale testing (Phase 3)Active Not RecruitingNCT04662710
What this trial is testing

Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) Plus Chemotherapy in Participants With Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-7902-015/E7080-G000-321/LEAP-015)

Who this might be right for
Advanced/Metastatic Gastroesophageal Adenocarcinoma
Merck Sharp & Dohme LLC 895
Testing effectiveness (Phase 2)Study completedNCT02255097
What this trial is testing

Study of MK-3475 (Pembrolizumab) in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma After Treatment With Platinum-based and Cetuximab Therapy (MK-3475-055/KEYNOTE-055)

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 172
Large-scale testing (Phase 3)Active Not RecruitingNCT05899049
What this trial is testing

Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, vs Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)-China Extension Study

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 249
Large-scale testing (Phase 3)Study completedNCT03361865
What this trial is testing

Pembrolizumab in Combination With Epacadostat or Placebo in Cisplatin-ineligible Urothelial Carcinoma (KEYNOTE-672/ECHO-307)

Who this might be right for
UC (Urothelial Cancer)
Incyte Corporation 93
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