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Results for “Lipoprotein Lipase Deficiency”

33 trials

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Showing 20 of 33 results

Large-scale testing (Phase 3)Study completedNCT02658175
What this trial is testing

The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 68
Testing effectiveness (Phase 2)Study completedNCT02767531
What this trial is testing

Orlistat for the Treatment of Type I Hyperlipoproteinemia

Who this might be right for
Hyperlipoproteinemia Type IHypertriglyceridemia
University of Texas Southwestern Medical Center 2
Not applicableStudy completedNCT02656095
What this trial is testing

Lipoprotein Lipase Enzyme Activity Assay Validation and Clinical Assessment

Who this might be right for
Lipoprotein Lipase Deficiency
University of Colorado, Denver 12
Testing effectiveness (Phase 2)Study completedNCT03360747
What this trial is testing

Phase 2 Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 3
Testing effectiveness (Phase 2)Study completedNCT01146522
What this trial is testing

Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia

Who this might be right for
Hyperlipoproteinemia
Novartis Pharmaceuticals 8
Large-scale testing (Phase 3)Study completedNCT00891306
What this trial is testing

Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects

Who this might be right for
Familial Lipoprotein Lipase Deficiency
Amsterdam Molecular Therapeutics 5
Not applicableApproved For MarketingNCT06360237
What this trial is testing

Olezarsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc.
Very early researchLooking for participantsNCT07371767
What this trial is testing

CS-121 APOC3 Base Editing in Children and Adolescents With Hyperchylomicronemia

Who this might be right for
Hyperchylomicronemia
Shanghai Jiao Tong University School of Medicine 15
Not applicableStudy completedNCT03912181
What this trial is testing

Medical Complications in Familial and Multifactorial Chylomicronaemia Syndromes

Who this might be right for
Familial Chylomicronemia SyndromeMultifactorial Chylomicronemia Syndrome
Hospices Civils de Lyon 140
Not applicableEnded earlyNCT01447901
What this trial is testing

Duration of Effect of Alipogene Tiparvovec Treatment, Which Was Administered in Other Studies

Who this might be right for
Hyperlipoproteinemia Type I
Amsterdam Molecular Therapeutics 19
Not applicableAvailableNCT06796426
What this trial is testing

Treatment Protocol of Plozasiran in Adults With High-Risk Severe Hypertriglyceridemia (SHTG) and in Adults and Adolescents With FCS

Who this might be right for
Familial ChylomicronemiaHigh Risk Severe Hypertriglyceridemia (SHTG)
Arrowhead Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT01514461
What this trial is testing

A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia Syndrome (FCS)
Novartis Pharmaceuticals 45
Not applicableWithdrawnNCT03198897
What this trial is testing

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)

Who this might be right for
Lipoprotein Lipase DeficiencyInborn Error of Lipid MetabolismCorneal Arcus
CENTOGENE GmbH Rostock
Early research (Phase 1)Study completedNCT03783377
What this trial is testing

Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
HypertriglyceridemiaFamilial Chylomicronemia
Arrowhead Pharmaceuticals 112
Not applicableStudy completedNCT04223908
What this trial is testing

InFocus France Epidemiological Study of Health Burden in Major Hypertriglyceridemia

Who this might be right for
Familial Chylomicronemia SyndromeMultifactorial Chylomicronemia Syndrome
New French Society of Atherosclerosis 52
Not applicableNo Longer AvailableNCT03544060
What this trial is testing

Volanesorsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia
Akcea Therapeutics
Large-scale testing (Phase 3)Active Not RecruitingNCT05185843
What this trial is testing

Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc. 24
Not applicableLooking for participantsNCT04227678
What this trial is testing

Postprandial Fatty Acid Metabolism in Subjects With Lipoprotein Lipase Deficiency

Who this might be right for
Lipoprotein Lipase Deficiency
Université de Sherbrooke 16
Testing effectiveness (Phase 2)WithdrawnNCT02904772
What this trial is testing

Alipogene Tiparvovec for the Treatment of LPLD Patients

Who this might be right for
LPL Deficiency
UniQure Biopharma B.V.
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
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