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Results for “Locally Advanced”

6,528 trials

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Showing 20 of 6,528 results

Testing effectiveness (Phase 2)Looking for participantsNCT05851924
What this trial is testing

NALIRIFOX in Combination With Radiation Therapy in People With Pancreatic Ductal Adenocarcinoma (PDAC)

Who this might be right for
Pancreatic Ductal Adenocarcinoma
Memorial Sloan Kettering Cancer Center 60
Early research (Phase 1)UnknownNCT04448379
What this trial is testing

Efficacy and Safety of JMT101 Combined With Afatinib (or Osimertinib) in Patients With Non-Small Cell Lung Cancer

Who this might be right for
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Shanghai JMT-Bio Inc. 48
Large-scale testing (Phase 3)Active Not RecruitingNCT04305496
What this trial is testing

Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Who this might be right for
Locally Advanced (Inoperable) or Metastatic Breast Cancer
AstraZeneca 818
Early research (Phase 1)Study completedNCT00003742
What this trial is testing

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Memorial Sloan Kettering Cancer Center
Large-scale testing (Phase 3)Not Yet RecruitingNCT07739186
What this trial is testing

A Study Evaluating BL-B01D1 in Combination With a PD-1/VEGF Bispecific Antibody Versus Tislelizumab Plus Platinum-doublet Chemotherapy as First-line Treatment for Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer(PANKU-Lung06)

Who this might be right for
Non-squamous Non-small Cell Lung Cancer
Sichuan Baili Pharmaceutical Co., Ltd. 120
Large-scale testing (Phase 3)Looking for participantsNCT07152405
What this trial is testing

BL-M07D1 Versus Investigator's Choice of Chemotherapy in Patients With HER2-positive Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Sichuan Baili Pharmaceutical Co., Ltd. 490
Not applicableLooking for participantsNCT04850729
What this trial is testing

Relationship Between Perioperative Treatment Efficacy and The Tumor Microenvironment for Locally Advanced Resectable Gastric Cancer.

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Nanfang Hospital, Southern Medical University 169
Testing effectiveness (Phase 2)Ended earlyNCT04375527
What this trial is testing

Binimetinib and Nivolumab for the Treatment of Locally Advanced Unresectable or Metastatic BRAF V600 Wildtype Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC V8Clinical Stage IV Cutaneous Melanoma AJCC V8Locally Advanced Cutaneous Melanoma+8 more
Jonsson Comprehensive Cancer Center 3
Not applicableStudy completedNCT05292027
What this trial is testing

Neoadjuvant Chemotherapy and Low-dose Radiotherapy Sequential Concurrent Chemoradiotherapy for Locally Advanced Nasopharyngeal Carcinoma

Who this might be right for
Nasopharyngeal Carcinoma
Sichuan Cancer Hospital and Research Institute 84
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07658183
What this trial is testing

A Clinical Trial Comparing the Efficacy and Safety of Different Doses of BL0175 Injection in Treating Postmenopausal Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Breast Cancer (Locally Advanced or Metastatic)
Shanghai Best-Link Bioscience, LLC 120
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06604351
What this trial is testing

Bronchoscopic Cryoablation Combined With Chemo-Immunotherapy in NSCLC With Central Airway Obstruction

Who this might be right for
Non-Small Cell Lung Cancer
Hunan Province Tumor Hospital 39
Testing effectiveness (Phase 2)Active Not RecruitingNCT05383196
What this trial is testing

Onvansertib + Paclitaxel In TNBC

Who this might be right for
Breast CancerInvasive Breast CancerUnresectable Breast Carcinoma+7 more
Antonio Giordano, MD 50
Large-scale testing (Phase 3)UnknownNCT02387086
What this trial is testing

Gefitinib Combined With Thalidomide to Treat NSCLC

Who this might be right for
NSCLC
Bai Jun 380
Testing effectiveness (Phase 2)Ended earlyNCT00319683
What this trial is testing

ADH300004 and 5-Fluorouracil in Locally Advanced, Recurrent, or Metastatic Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Adherex Technologies, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT06492005
What this trial is testing

A Clinical Study of 9MW2821 (and PD-1 Inhibitor) in Locally Advanced or Metastatic Triple-Negative Breast Cancer

Who this might be right for
Triple-Negative Breast Cancer
Mabwell (Shanghai) Bioscience Co., Ltd. 160
Testing effectiveness (Phase 2)UnknownNCT01090505
What this trial is testing

Study of S-1 and Oxaliplatin as Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer

Who this might be right for
Gastric Cancer
Chinese PLA General Hospital 160
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06508229
What this trial is testing

Adebrelimab Combined With Albumin Paclitaxel and Nedaplatin as Neoadjuvant Therapy for Locally Advanced Resectable ESCC

Who this might be right for
Esophageal Squamous Cell Carcinoma
Harbin Medical University 65
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07584031
What this trial is testing

Adebrelimab Plus Full-course Neoadjuvant Therapy for Resectable Locally Advanced ESCC (Phase 2)

Who this might be right for
ESCC
Tianjin Medical University Cancer Institute and Hospital 200
Not applicableWithdrawnNCT04670588
What this trial is testing

Response Assessment by Circulating Tumor DNA in Patients With Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Medical College of Wisconsin
Early research (Phase 1)Study completedNCT01988896
What this trial is testing

Study of Atezolizumab in Combination With Cobimetinib in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 153
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