Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced Adenocarcinoma”

1,186 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 1,186 results

Testing effectiveness (Phase 2)Looking for participantsNCT04165772
What this trial is testing

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

Who this might be right for
Rectal AdenocarcinomaClinical Stage: Stage II (T3-4, N-)Stage III (Any T, N+)+2 more
Memorial Sloan Kettering Cancer Center 200
Testing effectiveness (Phase 2)Ended earlyNCT05678257
What this trial is testing

NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal NeoplasmsColorectal Adenocarcinoma+2 more
NuCana plc 180
Testing effectiveness (Phase 2)Looking for participantsNCT06467565
What this trial is testing

NALIRIFOX as Induction Therapy in LAPC

Who this might be right for
Pancreatic Ductal Adenocarcinoma
The First Affiliated Hospital with Nanjing Medical University 20
Testing effectiveness (Phase 2)Study completedNCT01093222
What this trial is testing

Sorafenib Tosylate and Erlotinib Hydrochloride in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gallbladder Cancer or Cholangiocarcinoma

Who this might be right for
Extrahepatic Bile Duct AdenocarcinomaGallbladder AdenocarcinomaGallbladder Adenocarcinoma With Squamous Metaplasia+6 more
National Cancer Institute (NCI) 40
Early research (Phase 1)Study completedNCT05327231
What this trial is testing

IN10018 Monotherapy or in Combination With Docetaxel in Gastric or GEJ Adenocarcinoma

Who this might be right for
Gastric Cancer
InxMed (Shanghai) Co., Ltd. 33
Large-scale testing (Phase 3)Looking for participantsNCT06791512
What this trial is testing

MFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC

Who this might be right for
Colorectal Cancer (CRC)pMMR/MSS Adenocarcinoma of the Colon or Rectum
Jun Huang 166
Early research (Phase 1)Study completedNCT04641871
What this trial is testing

Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies

Who this might be right for
Metastatic CancerSolid Tumor
Symphogen A/S 78
Testing effectiveness (Phase 2)Looking for participantsNCT06576921
What this trial is testing

Efficacy and Safety of Serplulimab Combined With Chemotherapy as Neoadjuvant Treatment for Locally Advanced Gastric Cancer or Adenocarcinoma of Esophagogastric Junction

Who this might be right for
Stomach NeoplasmsImmune Checkpoint Inhibitors
Xijing Hospital 116
Testing effectiveness (Phase 2)UnknownNCT05528367
What this trial is testing

Tirelizumab in Combination With Chemoradiation in Patients With Unresectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Locally Advanced Gastric Cancer
Zhejiang Cancer Hospital 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT04864067
What this trial is testing

No Operation After Short Course Radiotherapy Followed By Consolidation Chemotherapy In Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Servicio de Salud Metropolitano Sur Oriente 73
Large-scale testing (Phase 3)Ended earlyNCT00097344
What this trial is testing

The CAT Study: Atamestane Plus Toremifene Versus Letrozole in Advanced Breast Cancer

Who this might be right for
Breast NeoplasmsNeoplasms, Hormone-Dependent
Intarcia Therapeutics 842
Testing effectiveness (Phase 2)Study completedNCT00022698
What this trial is testing

Capecitabine and Irinotecan in Treating Patients With Locally Advanced, Recurrent, or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 67
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07408609
What this trial is testing

Perioperative Chemotherapy With Low-Dose Radiotherapy and Tislelizumab for Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric or Gastroesophageal Junction Adenocarcinoma
Jiangsu Cancer Institute & Hospital 114
Testing effectiveness (Phase 2)Ended earlyNCT02254681
What this trial is testing

Low-Dose Radiation Therapy to the Whole Liver With Gemcitabine and Cisplatin in IHC

Who this might be right for
Intrahepatic Cholangiocarcinoma
Allina Health System 6
Post-approval studies (Phase 4)Not Yet RecruitingNCT07502027
What this trial is testing

A Clinical Study of Iparomlimab and Tuvonralimab Combined With SOX Following Heterogeneous Radiotherapy as First-line Treatment for Unresectable Locally Advanced or Metastatic HER2-negative Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric Cancer (Diagnosis)Gastric Cancer (GC)Gastroesophageal Junction Adenocarcinoma
Huazhong University of Science and Technology 55
Early research (Phase 1)Looking for participantsNCT07300241
What this trial is testing

Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

Who this might be right for
Clear Cell Renal Cell CarcinomaRenal Cell CarcinomaRCC+6 more
Neomorph, Inc 30
Testing effectiveness (Phase 2)Study completedNCT00560963
What this trial is testing

Treatment of Patients Suffering From a Progressive Pancreas Carcinoma With Everolimus (RAD001) and Gemcitabine

Who this might be right for
Advanced or Metastatic Pancreatic Adenocarcinoma
Novartis Pharmaceuticals 21
Early research (Phase 1)Looking for participantsNCT07348211
What this trial is testing

First in Human Study of SIM0610 in Solid Tumors

Who this might be right for
Advanced Solid TumoursNon-Small Cell Lung CancerColorectal Cancer+2 more
Jiangsu Simcere Pharmaceutical Co., Ltd. 260
Testing effectiveness (Phase 2)Study completedNCT00016900
What this trial is testing

PNU-93914 in Treating Patients With Locally Advanced or Metastatic Cancer of the Esophagus

Who this might be right for
Esophageal Cancer
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)UnknownNCT04999332
What this trial is testing

Perioperative Leucovorin, Oxaliplatin, Docetaxel and S-1 (LOTS) For Locally Advanced Gastric or Gastroesophageal Junction Cancer

Who this might be right for
Gastric CancerGastric AdenocarcinomaEffects of Chemotherapy+1 more
National Cheng-Kung University Hospital 58
Load More Results