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Results for “Locally Advanced Cancer”

6,077 trials

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Showing 20 of 6,077 results

Testing effectiveness (Phase 2)Study completedNCT01797900
What this trial is testing

The Role of Induction Chemotherapy for High-risk Locally Advanced Nasopharyngeal Carcinoma in the Era of IMRT

Who this might be right for
Nasopharyngeal Neoplasms
Chinese Academy of Medical Sciences 130
Testing effectiveness (Phase 2)Active Not RecruitingNCT05621707
What this trial is testing

Chemoradiotherapy Following Immunotherapy Plus Chemotherapy for Locally-advanced Esophageal Squamous Cell Cancer (RICE)

Who this might be right for
Esophageal Squamous Cell CarcinomasConcurrent ChemoradiotherapyImmunotherapy+1 more
Shanghai Chest Hospital 50
Testing effectiveness (Phase 2)Looking for participantsNCT06764355
What this trial is testing

Neoadjuvant Immunochemotherapy and Chemoradiotherapy Followed by Surgery for Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
ESCCTotal Neoadjuvant TreatmentPathological Complete Response
National Taiwan University Hospital 50
Not applicableActive Not RecruitingNCT02874885
What this trial is testing

Circulating Tumor Cells in Patients With Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal AdenocarcinomaMetastatic Rectal AdenocarcinomaRectosigmoid Adenocarcinoma+10 more
M.D. Anderson Cancer Center 341
Large-scale testing (Phase 3)Ended earlyNCT04335006
What this trial is testing

Study Comparing Carelizumab Plus Nab-paclitaxel and Apatinib, Carelizumab Plus Nab-paclitaxel, and Nab-paclitaxel in Patients With Advanced Triple Negative Breast Cancer.

Who this might be right for
Breast CancerTriple Negative Breast Cancer
Jiangsu HengRui Medicine Co., Ltd. 80
Not applicableStudy completedNCT02454647
What this trial is testing

Induction Chemotherapy, Chemoradiotherapy and Surgery in Locally Advanced Gastric Cancer Patients

Who this might be right for
Gastric CancerAdenocarcinomaEffects of Chemotherapy+2 more
Clinica Universidad de Navarra, Universidad de Navarra 46
Testing effectiveness (Phase 2)Study completedNCT00337649
What this trial is testing

Epothilone D in Combination With Herceptin (Trastuzumab) in Patients With HER-2 Positive Advanced or Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 27
Not applicableLooking for participantsNCT07133958
What this trial is testing

A Bidirectional Observational Clinical Study of NAIC in the Treatment of Tumor Regression Patterns in LA-OSCC and LA-OPSCC

Who this might be right for
Oral Squamous Cell Carcinoma (OSCC)Oropharyngeal Squamous Cell Carcinoma (SCC)
Zhujiang Hospital 35
Testing effectiveness (Phase 2)Study completedNCT04541355
What this trial is testing

Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin

Who this might be right for
Clinical Stage III Human Papillomavirus (HPV)-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Head and Neck Squamous Cell Carcinoma+26 more
Hyunseok Kang, MD
Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Testing effectiveness (Phase 2)Study completedNCT00301899
What this trial is testing

Trastuzumab and Pertuzumab in Treating Patients With Unresectable Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Previous Trastuzumab

Who this might be right for
Breast Cancer
National Institutes of Health Clinical Center (CC) 37
Large-scale testing (Phase 3)Study completedNCT03410693
What this trial is testing

Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Carcinoma, Transitional Cell
Bayer 175
Large-scale testing (Phase 3)Active Not RecruitingNCT04380636
What this trial is testing

Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)

Who this might be right for
Lung NeoplasmsCarcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC 870
Large-scale testing (Phase 3)UnknownNCT02409199
What this trial is testing

Apatinib Versus Docetaxol Patients With Advanced Gastric Cancer

Who this might be right for
Gastric Carcinoma
Shanghai Zhongshan Hospital 66
Early research (Phase 1)Looking for participantsNCT05857332
What this trial is testing

SG1906 for CLDN18.2-Positive Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors
Hangzhou Sumgen Biotech Co., Ltd. 60
Testing effectiveness (Phase 2)Looking for participantsNCT07332247
What this trial is testing

PD-1 Inhibitor Plus Chemotherapy Followed by Immediate Versus Selective Re-irradiation for Locally Advanced Recurrent NPC

Who this might be right for
Nasopharangeal CancerRecurrent Nasopharynx Carcinoma
Sun Yat-sen University 94
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07243938
What this trial is testing

Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET)

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Locally Advanced Gastric/Gastroesophageal Junction AdenocarcinomaMetastatic Colorectal Cancer (mCRC)+1 more
Tao Zhang 70
Testing effectiveness (Phase 2)Study completedNCT00867009
What this trial is testing

Induction and Maintenance Treatment of Advanced or Metastatic Non Squamous Non-Small Cell Lung Cancer

Who this might be right for
Non-Small-Cell Lung Cancer
Eli Lilly and Company 113
Testing effectiveness (Phase 2)Active Not RecruitingNCT06056804
What this trial is testing

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Beijing Friendship Hospital 20
Post-approval studies (Phase 4)Looking for participantsNCT05035147
What this trial is testing

Albumin-bound Paclitaxel Combined With Gemcitabine First-line Inoperable Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Tianjin Medical University Cancer Institute and Hospital 934
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