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Results for “Locally Advanced Disease”

4,490 trials

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Showing 20 of 4,490 results

Early research (Phase 1)UnknownNCT04448379
What this trial is testing

Efficacy and Safety of JMT101 Combined With Afatinib (or Osimertinib) in Patients With Non-Small Cell Lung Cancer

Who this might be right for
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Shanghai JMT-Bio Inc. 48
Not applicableLooking for participantsNCT04850729
What this trial is testing

Relationship Between Perioperative Treatment Efficacy and The Tumor Microenvironment for Locally Advanced Resectable Gastric Cancer.

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Nanfang Hospital, Southern Medical University 169
Testing effectiveness (Phase 2)Ended earlyNCT04375527
What this trial is testing

Binimetinib and Nivolumab for the Treatment of Locally Advanced Unresectable or Metastatic BRAF V600 Wildtype Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC V8Clinical Stage IV Cutaneous Melanoma AJCC V8Locally Advanced Cutaneous Melanoma+8 more
Jonsson Comprehensive Cancer Center 3
Not applicableStudy completedNCT05292027
What this trial is testing

Neoadjuvant Chemotherapy and Low-dose Radiotherapy Sequential Concurrent Chemoradiotherapy for Locally Advanced Nasopharyngeal Carcinoma

Who this might be right for
Nasopharyngeal Carcinoma
Sichuan Cancer Hospital and Research Institute 84
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07658183
What this trial is testing

A Clinical Trial Comparing the Efficacy and Safety of Different Doses of BL0175 Injection in Treating Postmenopausal Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Breast Cancer (Locally Advanced or Metastatic)
Shanghai Best-Link Bioscience, LLC 120
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06604351
What this trial is testing

Bronchoscopic Cryoablation Combined With Chemo-Immunotherapy in NSCLC With Central Airway Obstruction

Who this might be right for
Non-Small Cell Lung Cancer
Hunan Province Tumor Hospital 39
Testing effectiveness (Phase 2)Active Not RecruitingNCT05383196
What this trial is testing

Onvansertib + Paclitaxel In TNBC

Who this might be right for
Breast CancerInvasive Breast CancerUnresectable Breast Carcinoma+7 more
Antonio Giordano, MD 50
Testing effectiveness (Phase 2)Ended earlyNCT00319683
What this trial is testing

ADH300004 and 5-Fluorouracil in Locally Advanced, Recurrent, or Metastatic Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Adherex Technologies, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT06492005
What this trial is testing

A Clinical Study of 9MW2821 (and PD-1 Inhibitor) in Locally Advanced or Metastatic Triple-Negative Breast Cancer

Who this might be right for
Triple-Negative Breast Cancer
Mabwell (Shanghai) Bioscience Co., Ltd. 160
Testing effectiveness (Phase 2)UnknownNCT01090505
What this trial is testing

Study of S-1 and Oxaliplatin as Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer

Who this might be right for
Gastric Cancer
Chinese PLA General Hospital 160
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06508229
What this trial is testing

Adebrelimab Combined With Albumin Paclitaxel and Nedaplatin as Neoadjuvant Therapy for Locally Advanced Resectable ESCC

Who this might be right for
Esophageal Squamous Cell Carcinoma
Harbin Medical University 65
Not applicableWithdrawnNCT04670588
What this trial is testing

Response Assessment by Circulating Tumor DNA in Patients With Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Medical College of Wisconsin
Testing effectiveness (Phase 2)Study completedNCT06281886
What this trial is testing

Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell CarcinomaEfficacyToxicity
Sun Yat-sen University 170
Early research (Phase 1)Study completedNCT00033241
What this trial is testing

Erlotinib Combined With Gemcitabine in Treating Patients With Newly Diagnosed Locally Advanced or Metastatic Pancreatic Cancer or Other Solid Tumors

Who this might be right for
Pancreatic CancerUnspecified Adult Solid Tumor, Protocol Specific
OSI Pharmaceuticals
Testing effectiveness (Phase 2)Looking for participantsNCT07235566
What this trial is testing

MRG003 and Pucotenlimab to Treat Locally Advanced or Metastatic ATC/PDTC

Who this might be right for
Thyroid Cancer
Fudan University 60
Testing effectiveness (Phase 2)Looking for participantsNCT06732856
What this trial is testing

A Phase Ib/II Trial of Neoadjuvant Zolbetuximab Plus Docetaxel, Oxaliplatin and S-1 Chemotherapy in Patients With Locally Advanced Gastric Cancer

Who this might be right for
Stomach NeoplasmGastric (Stomach) Cancer
Asan Medical Center 57
Testing effectiveness (Phase 2)Looking for participantsNCT07646639
What this trial is testing

Different-Dose SCRT Plus CAPOX, PD-1 Blockade and IL-2 in LARC

Who this might be right for
Rectal CancerRadiotherapy
The First Affiliated Hospital with Nanjing Medical University 122
Large-scale testing (Phase 3)UnknownNCT02031939
What this trial is testing

Randomized Controlled Study on Optimize Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer

Who this might be right for
Advanced Rectal Cancer
Sun Yat-sen University 556
Not applicableLooking for participantsNCT04595929
What this trial is testing

Oncological Benefits of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) in Patients With T3-4 Gastric Cancer Cyt-

Who this might be right for
Peritoneal CarcinomatosisGastric Cancer
St. Petersburg State Pavlov Medical University 304
Testing effectiveness (Phase 2)Active Not RecruitingNCT04395677
What this trial is testing

AB-106 in Subjects With Advanced NSCLC Harboring ROS1 Fusion Gene

Who this might be right for
Non Small Cell Lung Cancer
Nuvation Bio Inc. 173
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